Thioacetamide-induced hepatocellular necrosis is attenuated in diet-induced obese mice

Journal of Toxicologic Pathology

Volumn 26, Issue 2, 2013, Pages 175-186

  Shirai, Makoto ^a   Arakawa, Shingo ^a   Miida, Hiroaki ^a   Matsuyama, Takuya ^a   Kinoshita, Junzo ^a   Makino, Toshihiko ^a   Kai, Kiyonori ^a   Teranishi, Munehiro ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

High fat diet; Liver; Mouse; Nonalcoholic fatty liver disease; Obese; Thioacetamide

Indexed keywords

CYTOCHROME P450 2E1; DRUG METABOLIZING ENZYME; GLUTATHIONE; GLUTATHIONE TRANSFERASE; THIOACETAMIDE; THIOACETAMIDE SULFOXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CHEMISTRY; BLOOD SAMPLING; BODY WEIGHT; CELL SWELLING; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIPID DIET; LIVER; LIVER CELL; LIVER CYTOSOL; LIVER MICROSOME; LIVER NECROSIS; MALE; MOUSE; NICK END LABELING; NONHUMAN; OBESITY; PROTEIN EXPRESSION; RODENT; TOXICOKINETICS; WESTERN BLOTTING;

EID: 84880627191     PISSN: 09149198     EISSN: None     Source Type: Journal    
DOI: 10.1293/tox.26.175     Document Type: Article

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