Ameliorative effects of vitamin C and E on serum lipid profiles and liver enzymes on fructose induced hyperglycaemia in wistar rats

Journal of Applied Pharmaceutical Science

Volumn 3, Issue 4SUPPL.1, 2013, Pages

  Tanko, Y ^a   Eze, E D ^a   Daja, H S ^a   Jimoh, A ^a   Mohammed, K A ^a   Musa, K Y ^a  

^a AHMADU BELLO UNIVERSITY   (Nigeria)

Author keywords

Fructose; Hyperglycemia; Lipid profile; Liver enzymes; Vitamin C; Vitamin E

Indexed keywords

EID: 84880625473     PISSN: None     EISSN: 22313354     Source Type: Journal    
DOI: 10.7324/JAPS.2013.34.S15     Document Type: Article

References (53)

1. Adaramoye, O.A., Osaimoje, D.O. and Akinsanya, M.A. Changes in antioxidant status and biochemical indices aft er acute administration of artemether, artemether-lumefantrine and halofantrine in rats. Basic and Clinical Pharmacology and Toxicology. 2008 ; 102: 412- 418.
2. Ambali, S., Akanbi, D., Igbokwe, N., Shittu, M., Kawu, M. and Ayo J. Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effect of vitamin C. J. Toxicol. Sci. 2007; 32: 111-120.
3. Ayo, JO., Minka, NS. and Mamman, M.M. Excitability scores of goats administered ascorbic acid and transported during hot-dry conditions. J Vet Sc. 2006; 7: 127-131.
4. Bantle, J.P., Raatz, S.K., Thomas, W. and Georgopoulos A. Effects of dietary fructose on plasma lipids in healthy subjects. American Journal of Clinical Nutrition. 2000 72:1128- 1134.
5. Beach, E.F. and Tuner J.J. An enzymatic method for glucose determination uptake in body fluids. Clinical Chemistry. 1958; 4: 462-468.
6. Beckman, J.A., Creager, M.A., Libby, P., Beck-Nielsen, H., Pedersen, O. and Linskov, H.O. Diabetes and atherosclerosis, Epid, Pathophysiology, and Impaired cellular insulin binding and insulin sensitivity induced by high-fructose feeding in normal subjects. American Journal of Clinical Nutrition. 1980 33:273-278
7. Bielski, B.H. Chemistry of ascorbic acid radicals. Ascorbic acid: chemistry, metabolism, and uses. Ado Chemical Series. 1982 ;200: 81-100.
8. Bodannes, R.S and Chan, P.C. Ascorbic acid as a scavenger of singlet oxygen. FEBS Letter. 1999 105: 195-196.
9. Bray, G.A., Nielsen, S.J. and Popkin, B.M. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. American Journal Clinical Nutrition, 2004;79:537- 543.
10. Chahil, T.J. and Ginsberg, H.N. Diabetic dyslipidemia. Endocrinol Metab Clin North Am 2006 ;35 (3), Pp. 491-510.
11. Chen, K., Suh, J., Carr, A.C. and Morrow, J.D. Vitamin C suppresses oxidative lipid damage in vivo, even in the presence of iron overload. Am J Physiol Endocrinol Metab, 2000 279: 1406-1412.
12. Chihuailaf, R.H., Contreras, P.A and Wittwer, F.G. Pathogenesis of oxidative stress: Consequences and evaluation in animal health. Vet Mex., 2002 33(3): 265-283.
13. Chow, C.K. Vitamin E and oxidative stress. Free Radical Biology and Medicine, 1991; 11: 215- 232.
14. Comte, C., Bellenger, S., Bellenger, J., Tessier, C., Poisson, J.P. and Narce, M. Effects of streptozotocin and dietary fructose on delta - 6 de saturation in spontaneously hypertensive rat liver. Biochimie, 2004; 86: 799 - 806.
15. Dias, A.S., Porawski,M., Alonso, M., Marroni, N., Collado, P.S. and Gonzalez-Gallego, J. Quercetin decreases oxidative stress, NF-kappa B activation and iNOS overexpression in liver of streptozotocin-induced diabetic rats. Journal of Nuturition., 2005; 135, 2299-2304.
16. Duncan, R.C., Knapp, R.G. and Miller, M.C. Test of hypothesis in population means. In: Introductory Biostatistics for the health sciences. John Wiley and Sons Inc. NY, 1977 pp 71-96.
17. Elliott, S., Keim, N., Stern, J., Teff, K. and Havel, P. Fructose, weight gain, and the insulin resistance syndrome.American Journal of Clinical Nutrition, 2002; 76 (5), 911-922.
18. Eze, E.D., Dawud, F.A., Zainab, A.A., Jimoh, A.,Malgwi, I.S. and Isa, A.S. Preliminary Studies of Effects of Vitamin C and Zinc on Some Liver Enzymes in Alloxan-induced Diabetic Wistar Rats. Asian Journal of Medical Sciences. 2012; 4(1): 17-22, 2012
19. Faeh, D., Minehira, K., Schwarz, J.M., Periasami, R., Seongsu, P.and Tappy, L. Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men. Diabetes, 2005 54:1907-1913
20. Frei, B. Efficacy of dietary antioxidants to prevent oxidative damage and inhibit chronic disease. Journal of Nutrition 2004; 134 (Suppl.): 3196- 3198.
21. Friedewald, W.T., Levy, R. and Fradrickson, D.S. Estimation of concentration of Low density lipoprotein cholesterol in plasma without the use of preparative ultracentrifugation. Clinical Chemistry.1972 19; 449- 452.
22. Gey, K.F. Vitamins E plus C and interacting conutrients required for optimal health. A critical and constructive review of epidemiology and supplementation data regarding cardiovascular disease and cancer. Biofactors; 1998; 7(1-2):113-74.
23. Giugliano, D. Dietary antioxidants for cardiovascular prevention. Nutritional and Metabolic Cardiovascular Diseases. 2000; 10(1):38-44.
24. Gumieniczek, A. Oxidative stress in kidney and liver of alloxan-induced diabetic rabbits: Effect of repaglinide. Acta Diabetol., 2005;42, 75-81.
25. Havel, P. Dietary Fructose: Implications for Dysregulation of Energy Homeostasis and Lipid/Carbohydrate Metabolism. Nutrition Reviews, 2005 ; 63:133-157.
26. Halliwell, B. Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Ageing, 2001; 18(9): 685-716.
27. Hemila, H., Roberts, P. and Wikstrom, M. Activated polymorphonuclear leucocytes consume vitamin C. FEBS Letter,1985; 178: 25-30.
28. Huang, Y.J., Fang, V.S., Juan, C.C., Chou, Y.C., Kwok, C.F.and Ho, L.T. Amelioration of insulin resistance and hypertension in a fructose-fed rat model with fish oil supplementation. Metabolism 1997 ;46:1252-1258, 1997
29. Idogun, E.S. and Ajala, M.O. Ascorbic acid and alpha tocopherol antioxidant status of type 2 diabetes mellitus patients seen in Lagos. Nig Postgrad Med J (2005);12: 155-157.
30. Klip, A. and Vranic, M. Muscle, liver and pancreas: Three Musketeers fighting to control glycemia. Am. J. Physiol. Endocrinol. Metab., 2006 ;291, 1141-1143.
31. Krauss., R.M., and Siri, P.W. Dyslipidemia in type 2 diabetes. Medical Clinics of North Ameriaca 2004; 88(4),Pp. 897-909.
32. Lewis, G.F., Carpentier, A., Khosrow, A. and Giacca, A. Disordered fat storage and mobilization in the Lipid Research Clinical Program 1984. The lipid Research Clinic Coronary Primary prevention trial results II. Journal of American. Medical Association.1984 251: 364 - 374.
33. Leeds, J.S., Forman, E.M, Morley, S., Scott, A.R., Tesfaye, S. and Sanders, D.S. Abnormal liver function tests in patients with Type 1 diabetes mellitus: Prevalence, clinical correlations and underlying pathologies. Diabet. Med., 2009 26, 1235-1241.
34. Marchesini, G., Brizi, M. and Bianchi, G. Nonalcoholic fatty liver disease. A feature of metabolic syndrome. Diabetes,2001; 50: 1844- 1850.
35. Maritz, G..S, and Van-Wyk, G. Influence of maternal nicotine exposure on neonatal rat lung structure: protective effect of ascorbic acid. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol, 1997; 117 : 159-65.
36. Miller, W., Katakam, P.V.G. and Ujhelyi, M. R.0 Impaired endothelium-mediated relaxation in coronary arteries from insulinresistant rats," Journal of Vascular Research, 1999; 36 (5) Pp 385-392.
37. Mohammed, H.A., Munavvar, A.S., and Edward, J.J. The Relation between Fructose-Induced Metabolic Syndrome and Altered Renal Haemodynamic and Excretory Function in the Rat: A Review Article. International Journal of Nephrology, 2011; 17-23.
38. Mooradian, A.D . Dsylipidemia in type 2 diabetes mellitus. Nature Clinical Practice Endocrinology & Metabolism, 2008; 5(3), 150- 159.
39. Nakanishi, N., Shiraishi, T. and Wada, M. Association between fasting glucose and C-reactive protein in a Japanese population: The Minoh study. Diabetes Research and Clinical Practice,2005 69: 88-98.
40. Odigie, IP., Okpoko, F.B. and Ojobor, P.D. Antioxidant eff ects of vitamin C and E on phenylhydrazine-induced haemolysis in Sprague Dawley rats: evidence for a better protection by vitamin E. Nig Postgrad Med J, 2007 ;14: 1-7.
41. Ostos, M.A., Recalde, D., Baroukh, N., Callejo, A., Rouis, M., Castro, G. and Zakin, M.M. Fructose Intake Increases Hyperlipidemia and Modifies Apolipoprotein Expression in Apolipoprotein AI-C III-AIV Transgenic Mice. The American Society for Nutritional Sciences. J. Nutr. 2002;132: 918 -923.
42. Pagliassotti, M.J.and. Horton T.J. Sucrose, insulin action and biologic complexity. Recent Research Development in Physiology. 2004 2:337-353, 2004
43. Parks, E.J. and Hellerstein, M.K. Carbohydrate-induced hypertriacylglycerolemia: historical perspective and review of biological mechanisms. American Journal of Clinical Nutrition, 2000; 71:412- 433.
44. Salwa, W.R. Health implications of fructose consumption: A review of recent data. Nutrition and Metabolism 2010;7:82.
45. Shekelle, P., Morton, S. and Hardy, M. Effect of Supplemental Antioxidants Vitamin C, Vitamin E, and Coenzyme Q10 for the Prevention and Treatment of Cardiovascular Disease. Evidence Report/Technology Assessment No. 83 (Prepared by Southern California-RAND 2003 Evidence based Practice Center, under Contract No 290-97- 0001). AHRQ Publication No. 03-E043. Rockville, MD: Agency for Healthcare Research and Quality.
46. Sies, H., Stahiadn, K.L. and Sundqwist, A.R. antioxidant Functions of Vitamins Vitamis E and C,betacarotene,and Other Carotenoids. Annals of New York Academy of Science, (1992); 669: 7-20.
47. Stein, E.A. Lipids, lipoproteins and Apolipoproteins. In: Treitz, N. W. (Ed). Fundamentals of Clinical Chemistry.(1987) 3rd Edn., W . B Sauders Philadelphia, pp; 470-479.
48. Taskinen, M.R. Diabetic dyslipidaemia: from basic research to clinical practice. Diabetologia. 2003; 46(6), 733-749.
49. Tietz, N.W. Clinical Guide to Laboratory Test, Second Edition W.B. Saunders Company, Philadelphia, U.S.A. (1990) ;554-556.
50. Upston, J.M., Terentis, A.C.and Stocker, R. Tocopherolmediated peroxidation of lipoproteins: implications for vitamin E as a potential antiatherogenic supplement. FASEB Journal. 1999;13:977- 94.
51. Wacnic, R.G., and Alber, J.J. A comprehensive evaluation of the heparin manganese precipitation procedure for estimating high density lipoprotein cholestsrol. Journal of Lipid Research, 1978;19: 65-76.
52. Wannamethee, S.G., Shaper, A.G., Lennon, L., and Whincup, P.H. Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men. Diabetes Care, 2005; 28: 2913-2918.
53. Yach, D., Hawkes, C., Gouuld, C.L. and Hofman, K.J. The Global Burden of Chronic Diseases. Overcoming the impediments to prevention and control. Journal of the American Medical Association, 2004; 291: 2616-2622.