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Volumn 30, Issue 1, 2013, Pages

The prognostic significance of p21 and Her-2 gene expression and mutation/polymorphism in patients with gastric adenocarcinoma

Author keywords

Gastric adenocarcinoma; Her 2 expression; Her 2 gene polymorphism; p21 expression; p21 gene mutation

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; PROTEIN P21; CYCLIN DEPENDENT KINASE INHIBITOR 1A; TUMOR MARKER;

EID: 84880585642     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-012-0357-y     Document Type: Article
Times cited : (12)

References (26)
  • 2
    • 50849123421 scopus 로고    scopus 로고
    • HER2 in gastric cancer: A new prognostic factor and a novel therapeutic target
    • 18441328 10.1093/annonc/mdn169 1:STN:280:DC%2BD1crivFajtQ%3D%3D
    • Gravalos C, Jimeno A. HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target. Ann Oncol. 2008;19:1523-9.
    • (2008) Ann Oncol , vol.19 , pp. 1523-1529
    • Gravalos, C.1    Jimeno, A.2
  • 3
    • 67650318738 scopus 로고    scopus 로고
    • Development of targeted therapies in advanced gastric cancer: Promising exploratory steps in a new era
    • 19412098 10.1097/CCO.0b013e32832c42e0 1:CAS:528:DC%2BD1MXnsVehsrc%3D
    • Wagner AD, Moehler M. Development of targeted therapies in advanced gastric cancer: promising exploratory steps in a new era. Curr Opin Oncol. 2009;21:381-5.
    • (2009) Curr Opin Oncol , vol.21 , pp. 381-385
    • Wagner, A.D.1    Moehler, M.2
  • 4
    • 0033959092 scopus 로고    scopus 로고
    • P21 expression is a prognostic factor in patients with p53-negative gastric cancer
    • 10695995 10.1016/S0304-3835(99)00335-3 1:CAS:528:DC%2BD3cXltVCgug%3D%3D
    • Xiangming C, Hokita S, Natsugoe S, Tanabe G, Baba M, Takao S, Kuroshima K, Aikou T. p21 expression is a prognostic factor in patients with p53-negative gastric cancer. Cancer Lett. 2000;148:181-8.
    • (2000) Cancer Lett , vol.148 , pp. 181-188
    • Xiangming, C.1    Hokita, S.2    Natsugoe, S.3    Tanabe, G.4    Baba, M.5    Takao, S.6    Kuroshima, K.7    Aikou, T.8
  • 8
    • 0028973212 scopus 로고
    • Overexpression of p21/Waf1/Cip1 induced growth arrest, giant cell formation and apoptosis in human breast carcinoma cell lines
    • Sheikh MS, Rochefort H, Garcia M. Overexpression of p21/Waf1/Cip1 induced growth arrest, giant cell formation and apoptosis in human breast carcinoma cell lines. Oncogene. 1995;11:1487-98.
    • (1995) Oncogene , vol.11 , pp. 1487-1498
    • Sheikh, M.S.1    Rochefort, H.2    Garcia, M.3
  • 9
    • 0028971751 scopus 로고
    • Direction of p21 generated signals towards cell growth or apoptosis is determined by protein kinase C and Bcl-2
    • Chen CY, Faller DV. Direction of p21 generated signals towards cell growth or apoptosis is determined by protein kinase C and Bcl-2. Oncogene. 1995;11:1675-83.
    • (1995) Oncogene , vol.11 , pp. 1675-1683
    • Chen, C.Y.1    Faller, D.V.2
  • 10
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip 1 is a potent inhibitor of G1 cyclin-dependent kinases
    • 8242751 10.1016/0092-8674(93)90499-G 1:CAS:528:DyaK2cXhtVShsLk%3D
    • Harper JW, Adami GR, Wei N, Keyomarsi K, Elledges SJ. The p21 Cdk-interacting protein Cip 1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 1993;75:805-16.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledges, S.J.5
  • 13
    • 0029984594 scopus 로고    scopus 로고
    • Inhibition of cell growth by transforming growth factor beta 1 is associated with p53-independent induction of p21 in gastric carcinoma cells
    • 8641969 10.1111/j.1349-7006.1996.tb00233.x 1:CAS:528:DyaK28XisFOht7k%3D
    • Akagi M, Yasui W, Akama Y, Yokozaki H, Tahara H, Haruma K, Kajiyama G, Tahara E. Inhibition of cell growth by transforming growth factor beta 1 is associated with p53-independent induction of p21 in gastric carcinoma cells. Jpn J Cancer Res. 1996;87:377-84.
    • (1996) Jpn J Cancer Res , vol.87 , pp. 377-384
    • Akagi, M.1    Yasui, W.2    Akama, Y.3    Yokozaki, H.4    Tahara, H.5    Haruma, K.6    Kajiyama, G.7    Tahara, E.8
  • 14
    • 0029847470 scopus 로고    scopus 로고
    • Expression of cyclin-dependent kinase inhibitor p21WAF1/CIP1 in non-neoplastic mucosa and neoplasia of the stomach: Relationship with p53 status and proliferative activity
    • 8976868 10.1002/(SICI)1096-9896(199610)180:2<122: AID-PATH647>3.0. CO;2-C 1:STN:280:DyaK2s7jtFaitA%3D%3D
    • Yasui W, Akama Y, Kuniyasu H, Yokozaki H, Semba S, Shimamoto F, Tahara E. Expression of cyclin-dependent kinase inhibitor p21WAF1/CIP1 in non-neoplastic mucosa and neoplasia of the stomach: relationship with p53 status and proliferative activity. J Pathol. 1996;180:122-8.
    • (1996) J Pathol , vol.180 , pp. 122-128
    • Yasui, W.1    Akama, Y.2    Kuniyasu, H.3    Yokozaki, H.4    Semba, S.5    Shimamoto, F.6    Tahara, E.7
  • 15
    • 2342419614 scopus 로고    scopus 로고
    • Expression of p21WAF1 and p53 and polymorphismof p21WAF1gene in gastric carcinoma
    • 15069711 1:CAS:528:DC%2BD2cXksFGltrw%3D
    • Xie HL, Su Q, He XS, Liang XO, Zhou JG, Song Y. Expression of p21WAF1 and p53 and polymorphismof p21WAF1gene in gastric carcinoma. World J Gastroenterol. 2004;10:1125-31.
    • (2004) World J Gastroenterol , vol.10 , pp. 1125-1131
    • Xie, H.L.1    Su, Q.2    He, X.S.3    Liang, X.O.4    Zhou, J.G.5    Song, Y.6
  • 16
    • 0030610068 scopus 로고    scopus 로고
    • Loss of p21 espression correlates with disease progression in gastric carcinoma
    • 9184177 10.1038/bjc.1997.276 1:CAS:528:DyaK2sXkt1Ontr8%3D
    • Ogawa M, Maeda K, Onoda N, Chung Y-S, Sowa M. Loss of p21 espression correlates with disease progression in gastric carcinoma. Br J Cancer. 1997;75:1617-20.
    • (1997) Br J Cancer , vol.75 , pp. 1617-1620
    • Ogawa, M.1    Maeda, K.2    Onoda, N.3    Chung, Y.-S.4    Sowa, M.5
  • 17
    • 0043287699 scopus 로고    scopus 로고
    • Prognostic significance of p21 and p53 expression in gastric cancer
    • 12872447 1:CAS:528:DC%2BD3sXlsFGltrk%3D
    • Seo YH, Joo YE, Choi SK, Rew JS, Park CS, Kim SJ. Prognostic significance of p21 and p53 expression in gastric cancer. Korean J Intern Med. 2003;18:98-103.
    • (2003) Korean J Intern Med , vol.18 , pp. 98-103
    • Seo, Y.H.1    Joo, Y.E.2    Choi, S.K.3    Rew, J.S.4    Park, C.S.5    Kim, S.J.6
  • 18
    • 33846001692 scopus 로고    scopus 로고
    • Relationship of hypoxia-inducible factor 1α and p21WAF1/CIP1 expression to cell apoptosis and clinical outcome in patients with gastric cancer
    • 17166265 10.1186/1477-7819-4-94
    • Mizokami K, Kakeji Y, Oda S, Maehara Y. Relationship of hypoxia-inducible factor 1α and p21WAF1/CIP1 expression to cell apoptosis and clinical outcome in patients with gastric cancer. World J Surg Oncol. 2006;4:94-101.
    • (2006) World J Surg Oncol , vol.4 , pp. 94-101
    • Mizokami, K.1    Kakeji, Y.2    Oda, S.3    Maehara, Y.4
  • 19
    • 0031009467 scopus 로고    scopus 로고
    • Expression of p21, but not p53 protein, is a factor in the survival of patients with advanced gastric carcinoma
    • 9179052 10.1002/(SICI)1097-0142(19970601)79:11<2067: AID-CNCR3>3.0.CO;2-M 1:CAS:528:DyaK2sXjs1yksL4%3D
    • Gomyo Y, Ikeda M, Osaki M, Tatebe S, Tsujitani S, Ikeguchi M, Kaibara N, Ito H. Expression of p21, but not p53 protein, is a factor in the survival of patients with advanced gastric carcinoma. Cancer. 1997;79:2067-72.
    • (1997) Cancer , vol.79 , pp. 2067-2072
    • Gomyo, Y.1    Ikeda, M.2    Osaki, M.3    Tatebe, S.4    Tsujitani, S.5    Ikeguchi, M.6    Kaibara, N.7    Ito, H.8
  • 20
    • 17944388015 scopus 로고    scopus 로고
    • Expression of cell-cycle regulatory proteins cyclin D1, cyclin E, and their inhibitor p21 WAF1/CIP1 in gastric cancer
    • 10547573 10.1002/(SICI)1096-9896(199910)189:2<186: AID-PATH418>3.0.CO;2-L
    • Müller W, Noguchi T, Wirtz HC, Hommel G, Gabbert HE. Expression of cell-cycle regulatory proteins cyclin D1, cyclin E, and their inhibitor p21 WAF1/CIP1 in gastric cancer. J Pathol. 1999;189:186-93.
    • (1999) J Pathol , vol.189 , pp. 186-193
    • Müller, W.1    Noguchi, T.2    Wirtz, H.C.3    Hommel, G.4    Gabbert, H.E.5
  • 21
    • 0032177726 scopus 로고    scopus 로고
    • P21 expression and mutation in gastric carcinoma: Analysis by immunohistochemistry and PCR-SSCP
    • 9811180 1:CAS:528:DyaK1cXnt1Kkuro%3D
    • Park YE, Choi KC, Choi YH. p21 expression and mutation in gastric carcinoma: analysis by immunohistochemistry and PCR-SSCP. J Korean Med Sci. 1998;13:507-12.
    • (1998) J Korean Med Sci , vol.13 , pp. 507-512
    • Park, Y.E.1    Choi, K.C.2    Choi, Y.H.3
  • 22
    • 0028173379 scopus 로고
    • Comparison of c-erbB-2 oncoprotein expression in tissue and serum of patients with stomach cancer
    • 10.1159/000217904
    • Chariylertsak S, Sugano K, Ohkura H, Mari Y. Comparison of c-erbB-2 oncoprotein expression in tissue and serum of patients with stomach cancer. Tumour Biol. 1994;15:294-303.
    • (1994) Tumour Biol , vol.15 , pp. 294-303
    • Chariylertsak, S.1    Sugano, K.2    Ohkura, H.3    Mari, Y.4
  • 23
    • 0025974889 scopus 로고
    • Evalution of immünreactivity for c-erbB-2 protein as a marker of poor short term prognosis in gastric cancer
    • 1670998 1:STN:280:DyaK3M7gsFKqsw%3D%3D
    • Yonemura Y, Ninomiya I, Yamaguchi A. Evalution of immünreactivity for c-erbB-2 protein as a marker of poor short term prognosis in gastric cancer. Cancer Res. 1991;51:1034-8.
    • (1991) Cancer Res , vol.51 , pp. 1034-1038
    • Yonemura, Y.1    Ninomiya, I.2    Yamaguchi, A.3
  • 24
    • 0025881623 scopus 로고
    • Expression of c-erbB-2 oncoprotein in gastric carcinoma. İmmünreactivity for c-erbB-2 protein is an indipentent indicatör of poor short-term prognosis in patients with gastric carcinoma
    • 1673870 10.1002/1097-0142(19910601)67:11<2914: AID- CNCR2820671134>3.0.CO;2-G 1:STN:280:DyaK3M3itlCrsg%3D%3D
    • Yonemura Y, Ninomiya I, Ohoyama S, Kimura H, Yamaguchi A, Fushida S, Kosaka T, Miwa K, Miyazaki I, Endou Y. Expression of c-erbB-2 oncoprotein in gastric carcinoma. İmmünreactivity for c-erbB-2 protein is an indipentent indicatör of poor short-term prognosis in patients with gastric carcinoma. Cancer. 1991;67:2914-8.
    • (1991) Cancer , vol.67 , pp. 2914-2918
    • Yonemura, Y.1    Ninomiya, I.2    Ohoyama, S.3    Kimura, H.4    Yamaguchi, A.5    Fushida, S.6    Kosaka, T.7    Miwa, K.8    Miyazaki, I.9    Endou, Y.10
  • 25
    • 0027219281 scopus 로고
    • Relationship of c-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer
    • 8397058 10.1002/1097-0142(19931001)72:7<2083: AID-CNCR2820720705>3. 0.CO;2-1 1:STN:280:DyaK3szos1KgsQ%3D%3D
    • Mizutani T, Onda M, Tokunaga A, Yamanaka N, Sugisaki Y. Relationship of c-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer. Cancer. 1993;72:2083-8.
    • (1993) Cancer , vol.72 , pp. 2083-2088
    • Mizutani, T.1    Onda, M.2    Tokunaga, A.3    Yamanaka, N.4    Sugisaki, Y.5
  • 26
    • 33745062806 scopus 로고    scopus 로고
    • Investigation of HER-2 codon 655 single nucleotide polymorphism frequency and c-ErbB-2 protein expression alterations in gastric cancer patients
    • 16718853 1:CAS:528:DC%2BD28Xmtl2gt70%3D
    • Satiroglu-Tufan NL, Bir F, Calli-Demirkan N. Investigation of HER-2 codon 655 single nucleotide polymorphism frequency and c-ErbB-2 protein expression alterations in gastric cancer patients. World J Gastroenterol. 2006;12:3283-7.
    • (2006) World J Gastroenterol , vol.12 , pp. 3283-3287
    • Satiroglu-Tufan, N.L.1    Bir, F.2    Calli-Demirkan, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.