A concept of eliminating nonhomologous recombination for scalable and safe AAV vector generation for human gene therapy

Nucleic Acids Research

Volumn 41, Issue 13, 2013, Pages 6609-6617

  Dong, Biao ^a   Moore, Andrea R ^a   Dai, Jihong ^a   Roberts, Sean ^a   Chu, Kirk ^a   Kapranov, Philipp ^b   Moss, Bernard ^c   Xiao, Weidong ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b St Laurent Institute   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; ENHANCED GREEN FLUORESCENT PROTEIN; GENOMIC DNA; PARVOVIRUS VECTOR; PROTEIN VP1; PROTEIN VP2; PROTEIN VP3; VIRUS PROTEIN;

ARTICLE; CAP GENE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DNA VECTOR; GENE EXPRESSION; GENE THERAPY; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; POXVIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REP GENE; RNA SPLICING; VIRAL GENE DELIVERY SYSTEM; VIRUS GENE; VIRUS GENOME; VIRUS REPLICATION;

CYTOPLASM; DEPENDOVIRUS; GENETIC THERAPY; GENETIC VECTORS; GENOME, VIRAL; HEK293 CELLS; HELA CELLS; HELPER VIRUSES; HUMANS; RECOMBINATION, GENETIC; VACCINIA VIRUS;

EID: 84880550933     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt404     Document Type: Article

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