The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription

Journal of Biological Chemistry

Volumn 288, Issue 29, 2013, Pages 20908-20917

  Song, Tanjing ^a   Yang, Leixiang ^a   Kabra, Neha ^a   Chen, Lihong ^a   Koomen, John ^a   Haura, Eric B ^a   Chen, Jiandong ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE; RIBOSOMAL RNA; RRNA TRANSCRIPTION; TUMOR DEVELOPMENT;

BIOCHEMISTRY;

RNA;

DOXORUBICIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE 1; RIBOSOME RNA; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DEACETYLATION; DNA DAMAGE; ENZYME KINETICS; ENZYME SYNTHESIS; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSFORMATION; HETEROZYGOSITY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

GLUCOSE; GLUCOSE DEPRIVATION; NAD; NML; NMNAT1; NUCLEOLUS; RIBOSOMAL RNA (RRNA); SIRT1;

ACETYLATION; CELL DEATH; CELL LINE, TUMOR; CELL NUCLEOLUS; DNA DAMAGE; DOWN-REGULATION; DOXORUBICIN; GENE DOSAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; GLUCOSE; HUMANS; METHYLTRANSFERASES; NAD; NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE; NUCLEAR PROTEINS; PROTEIN BINDING; RNA, RIBOSOMAL; SIRTUIN 1; TRANSCRIPTION, GENETIC;

EID: 84880538044     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.470302     Document Type: Article

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