Pressure-sensitive mucoadhesive polymer-based dental patches to treat periodontal diseases: An in vitro study

Drug Delivery

Volumn 20, Issue 6, 2013, Pages 258-267

  Manasadeepa, R ^a   Paul, Paramita ^a   Mukherjee, Biswajit ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

Bioadhesive strength; Dental pain management; Mucoadhesive; Periodontal diseases; Pressure sensitive adhesives; Release enhancers

Indexed keywords

ADHESIVE AGENT; AMOXICILLIN; DICLOFENAC; ETHYL CELLULOSE; EXCIPIENT; MACROGOL; POLYMER; POLYSORBATE 80; POLYVINYL ALCOHOL; POVIDONE;

ABSORPTION; ARTICLE; CHEEK MUCOSA; DENTAL PATCH; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG DOSAGE FORM; DRUG RELEASE; DRUG STABILITY; ENDURANCE; IN VITRO STUDY; MOISTURE; MUCOSA; PERIODONTAL DISEASE; PH; PRIORITY JOURNAL; SALIVA; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TEMPERATURE DEPENDENCE; THICKNESS;

ADHESIVENESS; ADMINISTRATION, BUCCAL; AMOXICILLIN; ANIMALS; DICLOFENAC; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EXCIPIENTS; GOATS; MOUTH MUCOSA; PERIODONTAL DISEASES; POLYMERS; PRESSURE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84880524866     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2013.823330     Document Type: Article

References (44)

1. Abu-Huwaij R, Obaidat RM, Sweidan K, Al-Hiari Y. (2011). Formulation and in vitro evaluation of xanthan gum or carbopol 934-based mucoadhesive patches, loaded with nicotine. AAPS Pharm Sci Tech 12:21-7.
2. Ahuja A, Ali J, Rahman S. (2006). Biodegradable periodontal intrapocket device containing metronidazole and amoxycillin: formulation and characterization. Pharmazie 61:25-9.
3. Andrews GP, Laverty TP, Jones DS. (2009). Mucoadhesive polymeric platforms for controlled drug delivery. Eur J Pharm Biopharm 71: 505-18.
4. Arora P, Mukherjee B. (2002). Design, development, physicochemical and in vitro and in vivo evaluation of transdermal patches containing diclofenac diethylammonium salt. J Pharm Sci 91:2076-89.
5. Baddupalli B, Mohammed ZNK, Ravindar Nath A, Banji D. (2010). Mucoadhesive drug delivery system: an overview. J Adv Pharm Tech Res 1:381-7.
6. Bascones MA, Figuero RE. (2004). Periodontal diseases: microbiological considerations. Med Oral Patol Oral Cir Bucal 9:S75-91.
7. Basu S, Mukherjee B, Chowdhury SR, et al. (2012). Colloidal goldloaded, biodegradable, polymer-based stavudine nanoparticle uptake by macrophages: an in vitro study. Int J Nanomedicine 7:6049-61.
8. Bruschi ML, Freitas OD. (2005). Oral bioadhesive drug delivery systems. Drug Dev Ind Pharm 31:293-310.
9. Bucci R, Magri AD, Magri AL. (1998). Determination of diclofenac salts in pharmaceutical formulations. Fresenius J Anal Chem 362:577-82.
10. Cavallari C, Fini A, Ospitali F. (2013). Mucoadhesive multiparticulate patch for the intrabuccal controlled delivery of lidocaine. Eur J Pharm Biopharm 83:405-14.
11. Chopparapu KS, Reddy PC, Doodipala N, Rao YM. (2012). Development of promethazine hydrochloride mucoadhesive patches for buccal delivery: in vitro, ex vivo and in vivo characterization. Int J Pharm Sci Nanotech 5:1697-705.
12. Costa P, Lobo JMS. (2001). Modeling and comparison of dissolution profiles. Eur J Pharm Sci 13:123-33.
13. Damodharan N, Roy G, Ghosh S, Mukherjee B. (2010). Skin permeation of rosiglitazone from transdermal matrix patches. Pharm Technol 34: 56-72.
14. Escobar-Chávez JJ, Rodr?́guez-Cruz IM, Dom?́nguez- Delgado CL. (2012). Chemical and physical enhancers for transdermal drug delivery In Gallelli L, ed. Pharmacology. Serbia: InTech, Inc., 397-434.
15. Gandhi RB, Robinson JR. (1994). Oral cavity as a site for bioadhesive drug delivery. Adv Drug Deliv Rev 13:43-74.
16. Ghosh S, Roy G, Mukherjee B. (2009). Dental mold: a novel formulation to treat common dental disorders. AAPS Pharm Sci Tech 10:692-702.
17. Gupta A, Garg S, Khar RK. (1992). Measurement of bioadhesive buccal tablets: design of an in vitro assembly. Indian Drugs 30:152-5.
18. Gupta R, Mukherjee B. (2003). Development and in vitro evaluation of diltiazem hydrochloride transdermal patches based on povidoneethylcellulose matrices. Drug Dev Ind Pharm 29:1-7.
19. Hearnden V, Sankar V, Hull K, et al. (2012). New developments and opportunities in oral mucosal drug delivery for local and systemic disease. Adv Drug Deliv Rev 64:16-28.
20. Herrera D, Alonso B, Leo'n R, et al. (2008). Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofilm. J Clin Periodontal 35:45-66.
21. Hoogstraate AJ, Verhoef JC, Tuk B, et al. (1996). Buccal delivery of fluorescein isothiocyanate-dextran 4400 and the peptide drug buserelin with glycodeoxycholate as an absorption enhancer in pigs. J Control Release 41:77-84.
22. International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. Stability testing of new drug substances and products Q1A (R2). Current Step 4 version dated 6 November 2003.
23. Khanna R, Agarwal SP, Ahuja A. (1997). Preparation and evaluation of mucoadhesive buccal films of clotrimazole for oral candida infections. Indian J Pharm Sci 59:299-305.
24. Lockhart PB, Brennan MT, Thornhill M, et al. (2009). Poor oral hygiene as a risk factor for infective endocarditis related bacteremia. Am Dent Assoc 140:1238-44.
25. Morales JO, McConville JT. (2011). Manufacture and characterization of mucoadhesive buccal films. Eur J Pharm Biopharm 77: 187-99.
26. Mukherjee B, Das S, Patra B, Layek B. (2006). Nefopam containing transdermal-matrix patches based on pressure-sensitive adhesive polymers. Pharm Technol 30:146-63.
27. Mukherjee B, Ghosh S, Das T, Doloi M. (2005). Characterization of insulin-like-growth factor II (IGF II) mRNA positive hepatic altered foci and IGF II expression in hepatocellular carcinoma during diethylnitrosamine-induced hepatocarcinogenesis in rats. J Carcinog 4:1-14.
28. Mukherjee B, Roy G, Ghosh S. (2009). Development of denticap, a matrix based sustained release formulation for treatment of toothache, dental infection and other gum problem. Curr Drug Deliv 6:199-207.
29. Mukherjee B, Santra K, Pattnaik G, Ghosh S. (2008). Preparation, characterization and in-vitro evaluation of sustained release proteinloaded nanoparticles based on biodegradable polymers. Int J Nanomedicine 3:487-96.
30. Nafee NA, Ismail FA, Boraie NA, Mortada LM. (2003). Design and characterization of mucoadhesive buccal patches containing cetylpyridinium. Acta Pharm 53:199-212.
31. Nafee NA, Ismail FA, Boraie NA, Mortada LM. (2004). Mucoadhesive buccal patches of miconazole nitrate: in vitro/in vivo performance and effect of ageing. Drug Dev Ind Pharm 30:985-93.
32. Nair AB, Kumria R, Harsha S, et al. (2013). In vitro techniques to evaluate buccal films. J Control Release 166:10-21.
33. Obaidat RM, Bader A, AL-Rajab W, et al. (2011). Preparation of mucoadhesive oral patches containing tetracycline hydrochloride and carvacrol for treatment of local mouth bacterial infections and candidiasis. Sci Pharm 79:197-212.
34. Özgüney IS, Karasulu HY, Kantarc| G, et al. (2006). Transdermal delivery of diclofenac sodium through rat skin from various formulations. AAPS Pharm Sci Tech 7:E1-7.
35. Paster BJ, Boches SK, Galvin JL, et al. (2001). Bacterial diversity in human subgingival plaque. J Bacteriol 183:3770-83.
36. Pattnaik G, Sinha B, Mukherjee B. (2012). Submicron-size biodegradable polymer-based didanosine particles for treating HIV at early stage: an in vitro study. J Microencapsul 29:666-76.
37. Pecsok RL, Shields LD, Cairns T, Mc William IG. (1968). Modern methods of chemical analysis. 2nd ed. New York, NY: John Wiley & Sons.
38. Priya S, Mahalaxmi R, Udupa N, et al. (2011). Preparation and evaluation of buccal mucoadhesive patch of betamethasone sodium phosphate for the treatment of oral submucous fibrosis. J Chem Pharm Res 3:56-65.
39. Puratchikody A, Prasanth VV, Mathew ST, Ashok Kumar B. (2011). Development and characterization of mucoadhesive patches of salbutamol sulfate for unidirectional buccal drug delivery. Acta Pharm 61:157-70.
40. Rudra A, Manasa Deepa R, Ghosh MK, et al. (2010). Doxorubicinloaded phosphatidylethanolamine conjugated nanoliposomes: in vitro characterization and their accumulation in liver, kidneys, and lungs in rats. Int J Nanomedicine 5:811-23.
41. Siegel IA, Izutsu KT, Watson E. (1981). Mechanisms of non-electrolyte penetration across dog and rabbit oral mucosa in vitro. Arch Oral Biol 26:357-61.
42. Silverstein RM, Webster FX. (1998). Spectrometric Identification of Organic Compounds. 6th ed. New York, NY: John Wiley & Sons.
43. Smart JD. (2005). The basics and underlying mechanisms of mucoadhesion. Adv Drug Deliv Rev 57:1556-68.
44. Tong DC, Rothwell BR. (2000). Antibiotic prophylaxis in dentistry: a review and practice recommendations. JADA 131:366-74.