Isolation and characterization of two geometric allene oxide isomers synthesized from 9S-hydroperoxylinoleic acid by cytochrome P450 CYP74C3: Stereochemical assignment of natural fatty acid allene oxides

Journal of Biological Chemistry

Volumn 288, Issue 29, 2013, Pages 20797-20806

  Brash, Alan R ^a   Boeglin, William E ^a   Stec, Donald F ^a   Voehler, Markus ^a   Schneider, Claus ^a   Cha, Jin K ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPENTENONES; CYTOCHROME P450; E CONFIGURATION; ISOLATION AND CHARACTERIZATION;

BIOCHEMISTRY; ISOMERS;

HYDROCARBONS;

9 HYDROPEROXYLINOLEIC ACID; ALLENE DERIVATIVE; CYCLOPENTENONE; CYCLOPENTENONE DERIVATIVE; CYTOCHROME P450; HEXANE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; BIOTRANSFORMATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; ENZYME ISOLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERIZATION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SEPARATION TECHNIQUE; STEREOCHEMISTRY; TEMPERATURE MEASUREMENT;

CYTOCHROME P450; LIPID OXIDATION; LIPID STRUCTURE; LIPOXYGENASE PATHWAY; NMR;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; CYCLIZATION; CYCLOPENTANES; CYTOCHROME P-450 ENZYME SYSTEM; EPOXY COMPOUNDS; FLAX; LINOLEIC ACIDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; OXYLIPINS; STEREOISOMERISM;

EID: 84880522135     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.482521     Document Type: Article

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