Investigation of substrate binding and product stereochemistry issues in two linoleate 9-lipoxygenases

Lipids

Volumn 43, Issue 11, 2008, Pages 979-987

  Boeglin, William E ^a   Itoh, Aya ^b,c   Zheng, Yuxiang ^a   Coffa, Gianguido ^a,d   Howe, Gregg A ^b,e   Brash, Alan R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c KEIO UNIVERSITY   (Japan)

^d Algenol Biofuels   (United States)

^e Michigan State University   (United States)

Author keywords

Anandamide; Arabidopsis; Chiral analysis; HODE; HPODE; Linoleic acid; Lipoxygenase; Stereochemistry; Tomato

Indexed keywords

ALANINE; ANANDAMIDE; ARACHIDONIC ACID; GLYCINE; HISTIDINE; HYDROPEROXIDE; HYDROPEROXYOCTADECADIENOIC ACID; LINOLEATE 9 LIPOXYGENASE; LINOLEIC ACID; OXYGENASE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARABIDOPSIS; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; ESCHERICHIA COLI; GENE MUTATION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PH MEASUREMENT; PROTEIN EXPRESSION; PROTEIN PURIFICATION; STEREOCHEMISTRY; SUBSTITUTION REACTION; TOMATO; WILD TYPE;

ALANINE; ARABIDOPSIS; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLYCINE; LINOLEIC ACID; LIPOXYGENASE; LYCOPERSICON ESCULENTUM; MUTATION; PHYLOGENY; PLANT PROTEINS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

ARABIDOPSIS; ARABIDOPSIS THALIANA; LYCOPERSICON ESCULENTUM;

EID: 55349121824     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-008-3230-1     Document Type: Article

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