-
1
-
-
47649115323
-
Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies
-
Antiretroviral Therapy Cohort Collaboration
-
Antiretroviral Therapy Cohort Collaboration. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet 2008; 372: 293-9.
-
(2008)
Lancet
, vol.372
, pp. 293-9
-
-
-
2
-
-
0037072066
-
Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies
-
Egger M, May M, Chene G et al. Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies. Lancet 2002; 360: 119-29.
-
(2002)
Lancet
, vol.360
, pp. 119-29
-
-
Egger, M.1
May, M.2
Chene, G.3
-
3
-
-
9844238154
-
Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study
-
Egger M, Hirschel B, Francioli P et al. Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study. Swiss HIV Cohort Study. BMJ 1997; 315: 1194-9.
-
(1997)
Swiss HIV Cohort Study. BMJ
, vol.315
, pp. 1194-9
-
-
Egger, M.1
Hirschel, B.2
Francioli, P.3
-
4
-
-
70049086591
-
Improvement of mitochondrial toxicity in patients receiving a nucleoside reversetranscriptase inhibitor-sparing strategy: results from the Multicenter Study with Nevirapine and Kaletra (MULTINEKA)
-
Negredo E, Miro O, Rodriguez-Santiago B et al. Improvement of mitochondrial toxicity in patients receiving a nucleoside reversetranscriptase inhibitor-sparing strategy: results from the Multicenter Study with Nevirapine and Kaletra (MULTINEKA). Clin Infect Dis 2009; 49: 892-900.
-
(2009)
Clin Infect Dis
, vol.49
, pp. 892-900
-
-
Negredo, E.1
Miro, O.2
Rodriguez-Santiago, B.3
-
5
-
-
64649106435
-
Peripheral and visceral fat changes following a treatment switch to a non-thymidine analogue or a nucleoside-sparing regimen in HIV-infected subjects with peripheral lipoatrophy: results of ACTG A5110
-
Tebas P, Zhang J, Hafner R et al. Peripheral and visceral fat changes following a treatment switch to a non-thymidine analogue or a nucleoside-sparing regimen in HIV-infected subjects with peripheral lipoatrophy: results of ACTG A5110. J Antimicrob Chemother 2009; 63: 998-1005.
-
(2009)
J Antimicrob Chemother
, vol.63
, pp. 998-1005
-
-
Tebas, P.1
Zhang, J.2
Hafner, R.3
-
6
-
-
84907817074
-
British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2012
-
Williams I, Churchill D, Anderson J et al. British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2012. HIV Med 2012; 13 Suppl 2: 1-6.
-
(2012)
HIV Med
, vol.13
, Issue.SUPPL 2
, pp. 1-6
-
-
Williams, I.1
Churchill, D.2
Anderson, J.3
-
7
-
-
65749098603
-
Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients
-
Vandekerckhove L, Verhofstede C, Vogelaers D. Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients. J Antimicrob Chemother 2009; 63: 1087-96.
-
(2009)
J Antimicrob Chemother
, vol.63
, pp. 1087-96
-
-
Vandekerckhove, L.1
Verhofstede, C.2
Vogelaers, D.3
-
8
-
-
54849146700
-
Maraviroc for previously treated patients with R5 HIV-1 infection
-
Gulick RM, Lalezari J, Goodrich J et al. Maraviroc for previously treated patients with R5 HIV-1 infection. N Engl J Med 2008; 359: 1429-41.
-
(2008)
N Engl J Med
, vol.359
, pp. 1429-41
-
-
Gulick, R.M.1
Lalezari, J.2
Goodrich, J.3
-
9
-
-
69849084582
-
Maraviroc: pharmacokinetics and drug interactions
-
Abel S, Back DJ, Vourvahis M. Maraviroc: pharmacokinetics and drug interactions. Antivir Ther 2009; 14: 607-18.
-
(2009)
Antivir Ther
, vol.14
, pp. 607-18
-
-
Abel, S.1
Back, D.J.2
Vourvahis, M.3
-
10
-
-
78549265829
-
Maraviroc is a substrate for OATP1B1 in vitro and maraviroc plasma concentrations are influenced by SLCO1B1 521 T
-
Siccardi M, D'Avolio A, Nozza S et al. Maraviroc is a substrate for OATP1B1 in vitro and maraviroc plasma concentrations are influenced by SLCO1B1 521 T.C polymorphism. Pharmacogenet Genomics 2010; 20: 759-65.
-
(2010)
C polymorphism. Pharmacogenet Genomics
, vol.20
, pp. 759-65
-
-
Siccardi, M.1
D'Avolio, A.2
Nozza, S.3
-
11
-
-
0030430035
-
Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
-
Kumar GN, Rodrigues D, Buko AM et al. Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J Pharmacol Exp Ther 1996; 277: 423-31.
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 423-31
-
-
Kumar, G.N.1
Rodrigues, D.2
Buko, A.M.3
-
12
-
-
84884915901
-
An open, randomised, 2-way crossover study to investigate the effect of darunavir/ritonavir on the pharmacokinetics of maraviroc in healthy subjects
-
In: Abstracts of the Eighth International Workshop on Clinical Pharmacology of HIV Therapy, Budapest, April Abstract 55
-
Abel S. An open, randomised, 2-way crossover study to investigate the effect of darunavir/ritonavir on the pharmacokinetics of maraviroc in healthy subjects. In: Abstracts of the Eighth International Workshop on Clinical Pharmacology of HIV Therapy, Budapest, April 2007. Abstract 55.
-
(2007)
-
-
Abel, S.1
-
13
-
-
78650205571
-
Two-year safety and virologic efficacy of maraviroc in treatment-experienced patients with CCR5-tropic HIV-1 infection: 96-week combined analysis of MOTIVATE 1 and 2
-
Hardy WD, Gulick RM, Mayer H et al. Two-year safety and virologic efficacy of maraviroc in treatment-experienced patients with CCR5-tropic HIV-1 infection: 96-week combined analysis of MOTIVATE 1 and 2. J Acquir Immune Defic Syndr 2010; 55: 558-64.
-
(2010)
J Acquir Immune Defic Syndr
, vol.55
, pp. 558-64
-
-
Hardy, W.D.1
Gulick, R.M.2
Mayer, H.3
-
14
-
-
77952108797
-
Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds
-
Else L, Watson V, Tjia J et al. Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds. J Chromatogr B Analyt Technol Biomed Life Sci 2010; 878: 1455-65.
-
(2010)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.878
, pp. 1455-65
-
-
Else, L.1
Watson, V.2
Tjia, J.3
-
15
-
-
84884922255
-
MVC 300 mg once daily+DRV/RTV 800/ 100 mg once daily provides MVC trough concentrations comparable to trough concentrations in HIV-1 patients taking MVC 300 mg twice daily+TVD: implications for Phase 3 studies
-
In: Eighteenth Conference on Retroviruses and Opportunistic Infections, Boston, MA, Poster 636. Foundation for Retrovirology and Human Health, Alexandria, VA, USA
-
Taylor S, Dufty N, Watson J. MVC 300 mg once daily+DRV/RTV 800/ 100 mg once daily provides MVC trough concentrations comparable to trough concentrations in HIV-1 patients taking MVC 300 mg twice daily+TVD: implications for Phase 3 studies. In: Eighteenth Conference on Retroviruses and Opportunistic Infections, Boston, MA, 2011. Poster 636. Foundation for Retrovirology and Human Health, Alexandria, VA, USA.
-
(2011)
-
-
Taylor, S.1
Dufty, N.2
Watson, J.3
-
16
-
-
40549135975
-
Assessment of the pharmacokinetics, safety and tolerability of maraviroc, a novel CCR5 antagonist, in healthy volunteers
-
Abel S, van der Ryst E, Rosario MC et al. Assessment of the pharmacokinetics, safety and tolerability of maraviroc, a novel CCR5 antagonist, in healthy volunteers. Br J Clin Pharmacol 2008; 65 Suppl 1: 5-18.
-
(2008)
Br J Clin Pharmacol
, vol.65
, Issue.SUPPL 1
, pp. 5-18
-
-
Abel, S.1
van der Ryst, E.2
Rosario, M.C.3
-
17
-
-
84884945699
-
Modeling of maraviroc pharmacokinetics in the presence of atazanavir/ritonavir in healthy volunteers and HIV-1-infected patients
-
In: Abstracts of the Twelfth International Workshop on Clinical Pharmacology of HIV Therapy, Miami, FL, 2011. Abstract P_05
-
Weatherley B, Vourvahis M, McFadyen L. Modeling of maraviroc pharmacokinetics in the presence of atazanavir/ritonavir in healthy volunteers and HIV-1-infected patients. In: Abstracts of the Twelfth International Workshop on Clinical Pharmacology of HIV Therapy, Miami, FL, 2011. Abstract P_05.
-
-
-
Weatherley, B.1
Vourvahis, M.2
McFadyen, L.3
-
18
-
-
84863199008
-
The MONET trial: week 144 analysis of the efficacy of darunavir/ritonavir (DRV/r) monotherapy versus DRV/r plus two nucleoside reverse transcriptase inhibitors, for patients with viral load ,50 HIV-1 RNA copies/mL at baseline
-
Arribas JR, Clumeck N, Nelson M et al. The MONET trial: week 144 analysis of the efficacy of darunavir/ritonavir (DRV/r) monotherapy versus DRV/r plus two nucleoside reverse transcriptase inhibitors, for patients with viral load ,50 HIV-1 RNA copies/mL at baseline. HIV Med 2012; 13: 398-405.
-
(2012)
HIV Med
, vol.13
, pp. 398-405
-
-
Arribas, J.R.1
Clumeck, N.2
Nelson, M.3
-
19
-
-
84856966336
-
Long-term efficacy of darunavir/ritonavir monotherapy in patients with HIV-1 viral suppression: week 96 results from the MONOI ANRS 136 study
-
Valantin MA, Lambert-Niclot S, Flandre P et al. Long-term efficacy of darunavir/ritonavir monotherapy in patients with HIV-1 viral suppression: week 96 results from the MONOI ANRS 136 study. J Antimicrob Chemother 2012; 67: 691-5.
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 691-5
-
-
Valantin, M.A.1
Lambert-Niclot, S.2
Flandre, P.3
-
20
-
-
84884945139
-
-
EMEA. CELSENTRI Scientific Discussion. 2007. (14 January 2013, date last accessed)
-
EMEA. CELSENTRI Scientific Discussion. 2007. http://www.ema.europa. eu/docs/en_GB/document_library/EPAR_-_Scientific_Discussion/human/00 0811/WC500022194.pdf (14 January 2013, date last accessed).
-
-
-
-
21
-
-
84856957465
-
Once daily maraviroc 300 mg or 150 mg in combination with ritonavir-boosted darunavir 800/100 mg
-
Okoli C, Siccardi M, Thomas-William S et al. Once daily maraviroc 300 mg or 150 mg in combination with ritonavir-boosted darunavir 800/100 mg. J Antimicrob Chemother 2012; 67: 671-4.
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 671-4
-
-
Okoli, C.1
Siccardi, M.2
Thomas-William, S.3
-
22
-
-
79955526585
-
Pharmacokinetic interactions of maraviroc with darunavir-ritonavir, etravirine, and etravirinedarunavir- ritonavir in healthy volunteers: results of two drug interaction trials
-
Kakuda TN, Abel S, Davis J et al. Pharmacokinetic interactions of maraviroc with darunavir-ritonavir, etravirine, and etravirinedarunavir- ritonavir in healthy volunteers: results of two drug interaction trials. Antimicrob Agents Chemother 2011; 55: 2290-6.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 2290-6
-
-
Kakuda, T.N.1
Abel, S.2
Davis, J.3
-
23
-
-
84884944341
-
-
Comparative Trial of Maraviroc versus Emtricitabine/Tenofovir both with Darunavir/Ritonavir in Antiretroviral-naive Patients Infected with CCR5 Tropic HIV 1 (MODERN). (14 January 2013, date last accessed)
-
Comparative Trial of Maraviroc versus Emtricitabine/Tenofovir both with Darunavir/Ritonavir in Antiretroviral-naive Patients Infected with CCR5 Tropic HIV 1 (MODERN). http://clinicaltrials.gov/ct2/show/study/ NCT01345630 (14 January 2013, date last accessed).
-
-
-
-
24
-
-
77950663633
-
The effects of a nucleoside-sparing antiretroviral regimen on the pharmacokinetics of ritonavir-boosted darunavir in HIV type-1-infected patients
-
Garvey L, Latch N, Erlwein OW et al. The effects of a nucleoside-sparing antiretroviral regimen on the pharmacokinetics of ritonavir-boosted darunavir in HIV type-1-infected patients. Antivir Ther 2010; 15: 213-8.
-
(2010)
Antivir Ther
, vol.15
, pp. 213-8
-
-
Garvey, L.1
Latch, N.2
Erlwein, O.W.3
-
25
-
-
33645795947
-
Pharmacokinetics of tenofovir disoproxil fumarate and ritonavir-boosted saquinavir mesylate administered alone or in combination at steady state
-
Chittick GE, Zong J, Blum MR et al. Pharmacokinetics of tenofovir disoproxil fumarate and ritonavir-boosted saquinavir mesylate administered alone or in combination at steady state. Antimicrob Agents Chemother 2006; 50: 1304-10.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1304-10
-
-
Chittick, G.E.1
Zong, J.2
Blum, M.R.3
-
26
-
-
2542502584
-
Interactions between atazanavir-ritonavir and tenofovir in heavily pretreated human immunodeficiency virus-infected patients
-
Taburet AM, Piketty C, Chazallon C et al. Interactions between atazanavir-ritonavir and tenofovir in heavily pretreated human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 2004; 48: 2091-6.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2091-6
-
-
Taburet, A.M.1
Piketty, C.2
Chazallon, C.3
-
27
-
-
84884962208
-
Pharmacokinetic evaluation of the combination of atazanavir, enteric coated didanosine and tenofovir disoproxil fumarate for a once daily antiretroviral regimen
-
In: Abstracts of the Forty-third Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, Abstract A-1616. American Society for Microbiology, Washington, DC, USA
-
Kaul S, Bassi K, Damle B. Pharmacokinetic evaluation of the combination of atazanavir, enteric coated didanosine and tenofovir disoproxil fumarate for a once daily antiretroviral regimen. In: Abstracts of the Forty-third Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, 2003. Abstract A-1616. American Society for Microbiology, Washington, DC, USA.
-
(2003)
-
-
Kaul, S.1
Bassi, K.2
Damle, B.3
-
28
-
-
34548572319
-
Tenofovir comedication does not impair the steady-state pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected adults
-
von Hentig N, Dauer B, Haberl A et al. Tenofovir comedication does not impair the steady-state pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected adults. Eur J Clin Pharmacol 2007; 63: 935-40.
-
(2007)
Eur J Clin Pharmacol
, vol.63
, pp. 935-40
-
-
von Hentig, N.1
Dauer, B.2
Haberl, A.3
-
29
-
-
34249984110
-
Pharmacokinetics of once-daily tenofovir, emtricitabine, ritonavir and fosamprenavir in HIV-infected subjects
-
Parks DA, Jennings HC, Taylor CW et al. Pharmacokinetics of once-daily tenofovir, emtricitabine, ritonavir and fosamprenavir in HIV-infected subjects. AIDS 2007; 21: 1373-5.
-
(2007)
AIDS
, vol.21
, pp. 1373-5
-
-
Parks, D.A.1
Jennings, H.C.2
Taylor, C.W.3
-
30
-
-
34548024165
-
Pharmacokinetic evaluation of emtricitabine in combination with other nucleoside antivirals in healthy volunteers
-
Zong J, Chittick GE, Wang LH et al. Pharmacokinetic evaluation of emtricitabine in combination with other nucleoside antivirals in healthy volunteers. J Clin Pharmacol 2007; 47: 877-89.
-
(2007)
J Clin Pharmacol
, vol.47
, pp. 877-89
-
-
Zong, J.1
Chittick, G.E.2
Wang, L.H.3
-
31
-
-
84884942677
-
-
Gilead. VIREAD Full Prescribing Information. (14 January 2013, date last accessed)
-
Gilead. VIREAD Full Prescribing Information. 2012. http://www.gilead. com/pdf/viread_pi.pdf (14 January 2013, date last accessed).
-
(2012)
-
-
-
32
-
-
84884911365
-
An investigation of the effects of tenofovir on the pharmacokinetics of the novel CCR5 inhibitor UK-427,857
-
In: Abstracts of the Seventh International Congress on Drug Therapy in HIV Infection, Glasgow, Abstract
-
Muirhead G. An investigation of the effects of tenofovir on the pharmacokinetics of the novel CCR5 inhibitor UK-427,857. In: Abstracts of the Seventh International Congress on Drug Therapy in HIV Infection, Glasgow, 2004. Abstract P282.
-
(2004)
, pp. 282
-
-
Muirhead, G.1
-
33
-
-
84859996096
-
Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration
-
Croteau D, Best BM, Letendre S et al. Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration. AIDS 2012; 26: 890-3.
-
(2012)
AIDS
, vol.26
, pp. 890-3
-
-
Croteau, D.1
Best, B.M.2
Letendre, S.3
-
34
-
-
43549094732
-
Class-sparing regimens for initial treatment of HIV-1 infection
-
Riddler SA, Haubrich R, DiRienzo AG et al. Class-sparing regimens for initial treatment of HIV-1 infection. N Engl J Med 2008; 358: 2095-106.
-
(2008)
N Engl J Med
, vol.358
, pp. 2095-106
-
-
Riddler, S.A.1
Haubrich, R.2
DiRienzo, A.G.3
-
35
-
-
53049083334
-
Initial therapy with nucleoside reverse transcriptase inhibitor-containing regimens is more effective than with regimens that spare them with no difference in short-term fat distribution: Hippocampe-ANRS 121 Trial
-
Duvivier C, Ghosn J, Assoumou L et al. Initial therapy with nucleoside reverse transcriptase inhibitor-containing regimens is more effective than with regimens that spare them with no difference in short-term fat distribution: Hippocampe-ANRS 121 Trial. J Antimicrob Chemother 2008; 62: 797-808.
-
(2008)
J Antimicrob Chemother
, vol.62
, pp. 797-808
-
-
Duvivier, C.1
Ghosn, J.2
Assoumou, L.3
-
36
-
-
80055028058
-
Efficacy of a nucleoside-sparing regimen of darunavir/ritonavir plus raltegravir in treatment-naive HIV-1-infected patients (ACTG A5262)
-
Taiwo B, Zheng L, Gallien S et al. Efficacy of a nucleoside-sparing regimen of darunavir/ritonavir plus raltegravir in treatment-naive HIV-1-infected patients (ACTG A5262). AIDS 2011; 25: 2113-22.
-
(2011)
AIDS
, vol.25
, pp. 2113-22
-
-
Taiwo, B.1
Zheng, L.2
Gallien, S.3
-
37
-
-
84855386789
-
Pharmacokinetic concerns related to the AIDS Clinical Trial Group (ACTG) A5262 trial
-
author reply 397-8
-
Gervasoni C, Cattaneo D. Pharmacokinetic concerns related to the AIDS Clinical Trial Group (ACTG) A5262 trial. AIDS 2012; 26: 398-400; author reply 397-8.
-
(2012)
AIDS
, vol.26
, pp. 398-400
-
-
Gervasoni, C.1
Cattaneo, D.2
|