Hydroxyaldimines as potent in vitro anticryptococcal agents

Letters in Applied Microbiology

Volumn 57, Issue 2, 2013, Pages 137-143

  Magalhaes T F F ^a   da Silva, C M ^a   De Fátima, Â ^a   da Silva, D L ^a   Modolo, L V ^a   Martins, C V B ^b   Alves, R B ^a   Ruiz, A L T G ^c   Longato, G B ^c   de Carvalho, J E ^c   de Resende Stoianoff, M A ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSIDADE ESTADUAL DO OESTE DO PARANÁ   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Aldimines; Anticryptococcal activity; Cryptococcus species; Schiff bases

Indexed keywords

ANTIFUNGAL AGENTS; CELL CULTURE; DRUG INTERACTIONS; FUNGI;

ALDIMINES; ANTICRYPTOCOCCAL ACTIVITY; ANTIFUNGAL DRUGS; CRYPTOCOCCUS SPECIES; CRYPTOCOCCUS SPP; FLUCONAZOLE; FUNGAL INFECTION; IN-VITRO; SCHIFF-BASE; SELECTIVITY INDEX;

LEAD COMPOUNDS;

ANTICRYPTOCOCCAL AGENT; ANTIFUNGAL AGENT; FLUCONAZOLE; HYDROXYALDIMINE DERIVATIVE; UNCLASSIFIED DRUG;

AMMONIUM COMPOUND; ANTIMICROBIAL ACTIVITY; BACTERIUM; BIOTECHNOLOGY; DISEASE RESISTANCE; DRUG; FUNGAL DISEASE; FUNGICIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIFUNGAL ACTIVITY; ANTIFUNGAL SUSCEPTIBILITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BROTH DILUTION; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS; CRYPTOCOCCUS GATTII; CRYPTOCOCCUS NEOFORMANS; FUNGAL STRAIN; HAPLORHINI; IN VITRO STUDY; IN VIVO STUDY; MINIMUM FUNGICIDAL CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

CRYPTOCOCCUS GATTII; FILOBASIDIELLA NEOFORMANS;

EID: 84880507463     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/lam.12086     Document Type: Article

References (25)

1. Chaturvedi, V. and Chaturvedi, S. (2011) Cryptococcus gattii: a resurgent fungal pathogen. Trends Microbiol 19, 564-571.
2. Chayakulkeeree, M. and Perfect, J.R. (2006) Cryptococcosis. Infect Dis Clin North Am 20, 507-544.
3. CLSI (2008) Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Approved Standard, 3rd edn. CLSI document M27-A3. Wayne, PA: Clinical and Laboratory Standards Institute.
4. Gopalakrishnan, M., Sureshkumar, P., Kanagarajan, V. and Thanusu, J. (2007) New environmentally friendly solvent-free synthesis of imines using calcium oxide under microwave irradiation. Res Chem Intermed 33, 541-548.
5. Hazen, K.C. (1998) Fungicidal versus fungistatic activity of terbinafine and itraconazole: an in vitro comparison. J Am Acad Dermatol 38, S37-S41.
6. Jesmin, M., Ali, M.M., Salahuddin, M.S., Habib, M.R. and Khanam, J.A. (2008) Antimicrobial activity of some Schiff bases derived from benzoin, salicylaldehyde, aminophenol and 2, 4-dinitrophenyl hydrazine. Mycobiology 36, 70-73.
7. Lin, X. (2009) Cryptococcus neoformans: morphogenesis, infection, and evolution. Infect Genet Evol 9, 401-416.
8. Martins, C.V.B., de Resende, M.A., Magalhães, T.F.F., Lima, B.H.S., Watanabe, G.A., Ruiz, A.L.T.G., de Carvalho, J.E., Pilli, R.A. et al. (2008) Antifungal activity of goniothalamin enantiomers. Lett Drug Des Discov 5, 74-78.
9. Martins, C.V.B., de Resende, M.A., da Silva, D.L., Magalhães, T.F.F., Modolo, L.V., Pilli, R.A. and de Fátima, Â. (2009) In vitro studies of anticandidal activity of goniothalamin enantiomers. J Appl Microbiol 107, 1279-1286.
10. Murayama, S., Sakai, S., Soeda, H., Yabuuchi, H., Masuda, K., Inoue, H., Watanabe, H. and Matsuo, Y. (2004) Pulmonary cryptococcosis in immunocompetent patients HRCT characteristics. J Clin Imaging 28, 191-195.
11. Obando, D., Pantarat, N., Handke, R., Koda, Y., Widmer, F., Djordjevic, J.T., Ellis, D.H., Sorrell, T.C. et al. (2009) Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes. Bioorg Med Chem 17, 6329-6339.
12. Oliveira, F.M., Severo, C.B., Guazzelli, L.S. and Severo, L.C. (2007) Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy. Rev Inst Med Trop Sao Paulo 49, 263-265.
13. Pannerselvam, P., Nair, R.R., Vijayalakshmi, G., Subramanian, E.H. and Sridhar, S.K. (2005) Synthesis of Schiff bases of 4-(4-aminophenyl)-morpholine as potential antimicrobial agents. Eur J Med Chem 40, 225-229.
14. Perfect, J.R. and Cox, G.M. (1999) Drug resistance in C. neoformans. Drug Resist Updat 2, 259-264.
15. Pfaller, M.A. (2012) Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment. Am J Med 125, S3-S13.
16. Pozio, E., Guarino, A., Pignata, C. and Morales, M.A.G. (1996) Possible development of resistance to fluconazole during suppressive therapy for AIDS-associated cryptococcal meningitis. Clin Infect Dis 23, 1337-1338.
17. Przbylski, P., Huczynski, A., Pyta, K., Brzezinski, B. and Franz, B. (2009) Biological properties of Schiff bases and azo derivatives of phenols. Curr Org Chem 13, 124-148.
18. Rehman, W., Baloch, M.K., Muhammad, B., Badshah, A. and Khan, K.M. (2004) Characteristic spectral studies and in vitro antifungal activity of some Schiff bases and their organotin (IV) complexes. Chin Sci Bull 49, 119-122.
19. Sakiyan, I., Loǧoǧlu, E., Arslan, S., Sari, N. and Şakiyan, N. (2004) Antimicrobial activities of N-(2-hydroxy-1-naphthalidene)-amino acid (glycine, phenylalanine, histidine, tryptophane) Schiff bases and their manganese(III) complexes. Biometals 17, 115-120.
20. da Silva, C.M., da Silva, D.L., Martins, C.V.B., de Rezende, M.A., Dias, E.S., Magalhães, T.F.F., Rodrigues, L.P., Sabino, A.A. et al. (2011a) Synthesis of aryl aldimines and their activity against fungi of clinical interest. Chem Biol Drug Des 78, 810-815.
21. da Silva, C.M., da Silva, D.L., Modolo, L.V., Alves, R.B., de Rezende, M.A., Martins, C.V.B. and de Fátima, Â. (2011b) Schiff bases: a short review of their antimicrobial activities. J Adv Res 2, 1-8.
22. Spellberg, B., Powers, J.H., Brass, E.P., Miller, L.G. and Edwards, J.E. Jr (2004) Trends in antimicrobial drug development: implications for the future. Clin Infect Dis 38, 1279-1286.
23. Subramanian, S. and Mathai, D. (2005) Clinical manifestations and management of cryptococcal infection. J Postgrad Med 51, 21-26.
24. Toenjes, K.A., Munsee, S.M., Ibrahim, A.S., Jeffrey, R., Edwards, J.E. Jr and Johnson, D.I. (2005) Small-molecule inhibitors of the budded-to-hyphal-form transition in the pathogenic yeast Candida albicans. Antimicrob Agents Chemother 49, 963-972.
25. Walsh, T.J. and Groll, A.H. (1999) Emerging fungal pathogens: evolving challenges to immunocompromised patients for the twenty-first century. Transpl Infect Dis 1, 247-261.