Identification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem and progenitor cells

Blood

Volumn 121, Issue 19, 2013, Pages 3838-3842

  Karlsson, Christine ^a   Baudet, Aurélie ^a   Miharada, Natsumi ^a   Soneji, Shamit ^b   Gupta, Rajeev ^b   Magnusson, Mattias ^a   Enver, Tariq ^b   Karlsson, Göran ^b   Larsson, Jonas ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD135 ANTIGEN; CD34 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCL28; THROMBOPOIETIN; UNCLASSIFIED DRUG; BETA CHEMOKINE; CCL28 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW BIOPSY; CELL PROLIFERATION; COLONY FORMING CELL; CYTOKINE RESPONSE; FETUS; FETUS LIVER; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENETIC ASSOCIATION; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL EXPANSION; SURVIVAL FACTOR; UMBILICAL CORD BLOOD CELL; XENOTRANSPLANTATION; ANIMAL; CELL CULTURE; CELL SURVIVAL; DRUG EFFECT; GENETICS; METABOLISM; NEWBORN; NONOBESE DIABETIC MOUSE; PHYSIOLOGY; STEM CELL; TRANSGENIC MOUSE;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINES, CC; HEMATOPOIETIC STEM CELLS; HUMANS; INFANT, NEWBORN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; STEM CELLS;

MLCS; MLOWN;

EID: 84880503246     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-02-481192     Document Type: Article

References (25)

1. Dahlberg A, Delaney C, Bernstein ID. Ex vivo expansion of human hematopoietic stem and progenitor cells. Blood. 2011;117(23):6083-6090.
2. Walasek MA, van Os R, de Haan G. Hematopoietic stem cell expansion: challenges and opportunities. Ann N Y Acad Sci. 2012;1266: 138-150.
3. Himburg HA, Muramoto GG, Daher P, et al. Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. Nat Med. 2010;16(4):475-482.
4. Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID. Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution. Nat Med. 2010;16(2):232-236.
5. Boitano AE, Wang J, Romeo R, et al. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science. 2010;329(5997):1345-1348.
6. Zhang CC, Kaba M, Iizuka S, Huynh H, Lodish HF. Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/ SCID transplantation. Blood. 2008;111(7): 3415-3423.
7. de Lima M, McMannis J, Gee A, et al. Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial. Bone Marrow Transplant. 2008;41(9):771-778.
8. Goessling W, Allen RS, Guan X, et al. Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 2011;8(4):445-458.
9. Huang J, Nguyen-McCarty M, Hexner EO, Danet-Desnoyers G, Klein PS. Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways. Nat Med. 2012;18(12): 1778-1785.
10. Gupta R, Hong D, Iborra F, Sarno S, Enver T. NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells. Science. 2007;316(5824):590-593.
11. Gammaitoni L, Weisel KC, Gunetti M, et al. Elevated telomerase activity and minimal telomere loss in cord blood long-term cultures with extensive stem cell replication. Blood. 2004; 103(12):4440-4448.
12. Ueda T, Yoshida M, Yoshino H, et al. Hematopoietic capability of CD341 cord blood cells: a comparison with CD341 adult bone marrow cells. Int J Hematol. 2001;73(4):457-462.
13. Lansdorp PM, Dragowska W, Mayani H. Ontogeny-related changes in proliferative potential of human hematopoietic cells. J Exp Med. 1993;178(3):787-791.
14. Keller JR, Ortiz M, Ruscetti FW. Steel factor (c-kit ligand) promotes the survival of hematopoietic stem/progenitor cells in the absence of cell division. Blood. 1995;86(5):1757-1764.
15. Kent DG, Dykstra BJ, Cheyne J, Ma E, Eaves CJ. Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic stem cells. Blood. 2008;112(3): 560-567.
16. Borge OJ, Ramsfjell V, Veiby OP, Murphy MJ Jr, Lok S, Jacobsen SE. Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro. Blood. 1996;88(8): 2859-2870.
17. Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005;102(43):15545-15550.
18. Wang W, Soto H, Oldham ER, et al. Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2). J Biol Chem. 2000;275(29): 22313-22323.
19. Pan J, Kunkel EJ, Gosslar U, et al. A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues. J Immunol. 2000;165(6):2943-2949.
20. Majeti R, Park CY, Weissman IL. Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell. 2007;1(6):635-645.
21. Ishikawa F, Yasukawa M, Lyons B, et al. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor gamma chain(null) mice. Blood. 2005;106(5): 1565-1573.
22. Söderberg SS, Karlsson G, Karlsson S. Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling. Ann N Y Acad Sci. 2009;1176:55-69.
23. Baudet A, Karlsson C, Safaee Talkhoncheh M, Galeev R, Magnusson M, Larsson J. RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion. Blood. 2012;119(26):6255-6258.
24. Nakayama T, Hieshima K, Izawa D, Tatsumi Y, Kanamaru A, Yoshie O. Cutting edge: profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues. J Immunol. 2003;170(3):1136-1140.
25. Facciabene A, Peng X, Hagemann IS, et al. Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature. 2011;475(7355):226-230.