메뉴 건너뛰기




Volumn 8, Issue 7, 2013, Pages

Passive Immunization with Hypochlorite-oxLDL Specific Antibodies Reduces Plaque Volume in LDL Receptor-Deficient Mice

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; HISTIDINE; HYPOCHLORITE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; LOW DENSITY LIPOPROTEIN RECEPTOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY A7S8; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; PHOSPHATE BUFFERED SALINE; UNCLASSIFIED DRUG; VALINE;

EID: 84880474367     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068039     Document Type: Article
Times cited : (14)

References (41)
  • 1
    • 79955604190 scopus 로고    scopus 로고
    • Anti-inflammatory therapeutics for the treatment of atherosclerosis
    • Charo IF, Taub R, (2011) Anti-inflammatory therapeutics for the treatment of atherosclerosis. Nat Rev Drug Discov 10: 365-376.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 365-376
    • Charo, I.F.1    Taub, R.2
  • 2
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: a double-edged sword
    • Hansson GK, Libby P, (2006) The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol 6: 508-519.
    • (2006) Nat Rev Immunol , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 3
    • 34247267297 scopus 로고    scopus 로고
    • Active and passive immunization for atherosclerosis
    • Chyu KY, Nilsson J, Shah PK, (2007) Active and passive immunization for atherosclerosis. Curr Opin Mol Ther 9: 176-182.
    • (2007) Curr Opin Mol Ther , vol.9 , pp. 176-182
    • Chyu, K.Y.1    Nilsson, J.2    Shah, P.K.3
  • 4
    • 69649089891 scopus 로고    scopus 로고
    • The therapeutic potential of targeting B cells and anti-oxLDL antibodies in atherosclerosis
    • van Leeuwen M, Damoiseaux J, Duijvestijn A, Tervaert JW, (2009) The therapeutic potential of targeting B cells and anti-oxLDL antibodies in atherosclerosis. Autoimmun Rev 9: 53-57.
    • (2009) Autoimmun Rev , vol.9 , pp. 53-57
    • van Leeuwen, M.1    Damoiseaux, J.2    Duijvestijn, A.3    Tervaert, J.W.4
  • 5
    • 33749147435 scopus 로고    scopus 로고
    • Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein E-null mice
    • Faria-Neto JR, Chyu KY, Li X, Dimayuga PC, Ferreira C, et al. (2006) Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein E-null mice. Atherosclerosis 189: 83-90.
    • (2006) Atherosclerosis , vol.189 , pp. 83-90
    • Faria-Neto, J.R.1    Chyu, K.Y.2    Li, X.3    Dimayuga, P.C.4    Ferreira, C.5
  • 7
    • 24744462348 scopus 로고    scopus 로고
    • Thematic review series: The Immune System and Atherogenesis. The role of natural antibodies in atherogenesis
    • Binder CJ, Shaw PX, Chang MK, Boullier A, Hartvigsen K, et al. (2005) Thematic review series: The Immune System and Atherogenesis. The role of natural antibodies in atherogenesis. J Lipid Res 46: 1353-1363.
    • (2005) J Lipid Res , vol.46 , pp. 1353-1363
    • Binder, C.J.1    Shaw, P.X.2    Chang, M.K.3    Boullier, A.4    Hartvigsen, K.5
  • 8
    • 0035573706 scopus 로고    scopus 로고
    • Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo
    • Shaw PX, Horkko S, Tsimikas S, Chang MK, Palinski W, et al. (2001) Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo. Arterioscler Thromb Vasc Biol 21: 1333-1339.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1333-1339
    • Shaw, P.X.1    Horkko, S.2    Tsimikas, S.3    Chang, M.K.4    Palinski, W.5
  • 9
    • 4043152981 scopus 로고    scopus 로고
    • IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis
    • Binder CJ, Hartvigsen K, Chang MK, Miller M, Broide D, et al. (2004) IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J Clin Invest 114: 427-437.
    • (2004) J Clin Invest , vol.114 , pp. 427-437
    • Binder, C.J.1    Hartvigsen, K.2    Chang, M.K.3    Miller, M.4    Broide, D.5
  • 10
    • 0038375997 scopus 로고    scopus 로고
    • Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL
    • Binder CJ, Horkko S, Dewan A, Chang MK, Kieu EP, et al. (2003) Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med 9: 736-743.
    • (2003) Nat Med , vol.9 , pp. 736-743
    • Binder, C.J.1    Horkko, S.2    Dewan, A.3    Chang, M.K.4    Kieu, E.P.5
  • 11
    • 0242381313 scopus 로고    scopus 로고
    • Immunoglobulin M Type of Autoantibodies to Oxidized Low-Density Lipoprotein Has an Inverse Relation to Carotid Artery Atherosclerosis
    • Karvonen J, Päivänsalo M, Kesäniemi YA, Hörkkö S, (2003) Immunoglobulin M Type of Autoantibodies to Oxidized Low-Density Lipoprotein Has an Inverse Relation to Carotid Artery Atherosclerosis. Circulation 108: 2107-2112.
    • (2003) Circulation , vol.108 , pp. 2107-2112
    • Karvonen, J.1    Päivänsalo, M.2    Kesäniemi, Y.A.3    Hörkkö, S.4
  • 12
    • 33746773033 scopus 로고    scopus 로고
    • Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension
    • Su J, Georgiades A, Wu R, Thulin T, de Faire U, et al. (2006) Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension. Atherosclerosis 188: 160-166.
    • (2006) Atherosclerosis , vol.188 , pp. 160-166
    • Su, J.1    Georgiades, A.2    Wu, R.3    Thulin, T.4    de Faire, U.5
  • 13
    • 71649096567 scopus 로고    scopus 로고
    • Low level natural antibodies against phosphorylcholine: A novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease
    • Frostegård J, (2010) Low level natural antibodies against phosphorylcholine: A novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease. Clinical Immunology 134: 47-54.
    • (2010) Clinical Immunology , vol.134 , pp. 47-54
    • Frostegård, J.1
  • 16
    • 0032701646 scopus 로고    scopus 로고
    • Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
    • Podrez EA, Schmitt D, Hoff HF, Hazen SL, (1999) Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro. J Clin Invest 103: 1547-1560.
    • (1999) J Clin Invest , vol.103 , pp. 1547-1560
    • Podrez, E.A.1    Schmitt, D.2    Hoff, H.F.3    Hazen, S.L.4
  • 17
    • 0028292033 scopus 로고
    • Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
    • Daugherty A, Dunn JL, Rateri DL, Heinecke JW, (1994) Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions. J Clin Invest 94: 437-444.
    • (1994) J Clin Invest , vol.94 , pp. 437-444
    • Daugherty, A.1    Dunn, J.L.2    Rateri, D.L.3    Heinecke, J.W.4
  • 19
    • 0035824162 scopus 로고    scopus 로고
    • Association between myeloperoxidase levels and risk of coronary artery disease
    • Zhang R, Brennan ML, Fu X, Aviles RJ, Pearce GL, et al. (2001) Association between myeloperoxidase levels and risk of coronary artery disease. Jama 286: 2136-2142.
    • (2001) Jama , vol.286 , pp. 2136-2142
    • Zhang, R.1    Brennan, M.L.2    Fu, X.3    Aviles, R.J.4    Pearce, G.L.5
  • 20
  • 21
    • 34447323030 scopus 로고    scopus 로고
    • Anti-oxidized low-density lipoprotein antibodies in myeloperoxidase-positive vasculitis patients preferentially recognize hypochlorite-modified low density lipoproteins
    • Slot MC, Theunissen R, van Paassen P, Damoiseaux JG, Cohen Tervaert JW, (2007) Anti-oxidized low-density lipoprotein antibodies in myeloperoxidase-positive vasculitis patients preferentially recognize hypochlorite-modified low density lipoproteins. Clin Exp Immunol 149: 257-264.
    • (2007) Clin Exp Immunol , vol.149 , pp. 257-264
    • Slot, M.C.1    Theunissen, R.2    van Paassen, P.3    Damoiseaux, J.G.4    Cohen Tervaert, J.W.5
  • 22
    • 70049101610 scopus 로고    scopus 로고
    • The IgM response to modified LDL in experimental atherosclerosis: hypochlorite-modified LDL IgM antibodies versus classical natural T15 IgM antibodies
    • van Leeuwen M, Damoiseaux J, Duijvestijn A, Heeringa P, Gijbels M, et al. (2009) The IgM response to modified LDL in experimental atherosclerosis: hypochlorite-modified LDL IgM antibodies versus classical natural T15 IgM antibodies. Ann N Y Acad Sci 1173: 274-279.
    • (2009) Ann N Y Acad Sci , vol.1173 , pp. 274-279
    • van Leeuwen, M.1    Damoiseaux, J.2    Duijvestijn, A.3    Heeringa, P.4    Gijbels, M.5
  • 25
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK, (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 26
    • 53349143955 scopus 로고    scopus 로고
    • anti-oxLDL antibody isotype levels, as potential markers for progressive atherosclerosis in APOE-/- and APOE-/-CD40L-/- mice
    • Smook M, van Leeuwen M, Damoiseaux J, Theunissen R, Daemen M, et al. (2008) anti-oxLDL antibody isotype levels, as potential markers for progressive atherosclerosis in APOE-/- and APOE-/-CD40L-/- mice. Clin Exp Immunol 154: 264-269.
    • (2008) Clin Exp Immunol , vol.154 , pp. 264-269
    • Smook, M.1    van Leeuwen, M.2    Damoiseaux, J.3    Theunissen, R.4    Daemen, M.5
  • 27
    • 1542698957 scopus 로고
    • Cloning immunoglobulin variable domains for expression by the polymerase chain reaction
    • Orlandi R, Gussow DH, Jones PT, Winter G, (1989) Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. Proc Natl Acad Sci U S A 86: 3833-3837.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 3833-3837
    • Orlandi, R.1    Gussow, D.H.2    Jones, P.T.3    Winter, G.4
  • 28
    • 11844258858 scopus 로고    scopus 로고
    • Restricted IgA repertoire in both B-1 and B-2 cell-derived gut plasmablasts
    • Stoel M, Jiang HQ, van Diemen CC, Bun JC, Dammers PM, et al. (2005) Restricted IgA repertoire in both B-1 and B-2 cell-derived gut plasmablasts. J Immunol 174: 1046-1054.
    • (2005) J Immunol , vol.174 , pp. 1046-1054
    • Stoel, M.1    Jiang, H.Q.2    van Diemen, C.C.3    Bun, J.C.4    Dammers, P.M.5
  • 29
    • 3242876679 scopus 로고    scopus 로고
    • IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis
    • Giudicelli V, Chaume D, Lefranc MP, (2004) IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis. Nucleic Acids Res 32: W435-440.
    • (2004) Nucleic Acids Res , vol.32
    • Giudicelli, V.1    Chaume, D.2    Lefranc, M.P.3
  • 30
    • 0035957021 scopus 로고    scopus 로고
    • Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice
    • von der Thusen JH, van Berkel TJ, Biessen EA, (2001) Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice. Circulation 103: 1164-1170.
    • (2001) Circulation , vol.103 , pp. 1164-1170
    • von der Thusen, J.H.1    van Berkel, T.J.2    Biessen, E.A.3
  • 31
    • 77956180166 scopus 로고    scopus 로고
    • Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions
    • Goossens P, Gijbels M, Zernecke A, Eijgelaar W, Vergouwe M, et al. (2010) Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions. Cell Metabolism 12: 142-153.
    • (2010) Cell Metabolism , vol.12 , pp. 142-153
    • Goossens, P.1    Gijbels, M.2    Zernecke, A.3    Eijgelaar, W.4    Vergouwe, M.5
  • 32
    • 0346727295 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice
    • Kanters E, Pasparakis M, Gijbels MJ, Vergouwe MN, Partouns-Hendriks I, et al. (2003) Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice. J Clin Invest 112: 1176-1185.
    • (2003) J Clin Invest , vol.112 , pp. 1176-1185
    • Kanters, E.1    Pasparakis, M.2    Gijbels, M.J.3    Vergouwe, M.N.4    Partouns-Hendriks, I.5
  • 33
    • 66449085101 scopus 로고    scopus 로고
    • Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans
    • Chou MY, Fogelstrand L, Hartvigsen K, Hansen LF, Woelkers D, et al. (2009) Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans. J Clin Invest 119: 1335-1349.
    • (2009) J Clin Invest , vol.119 , pp. 1335-1349
    • Chou, M.Y.1    Fogelstrand, L.2    Hartvigsen, K.3    Hansen, L.F.4    Woelkers, D.5
  • 34
    • 34347225913 scopus 로고    scopus 로고
    • Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study
    • Meuwese MC, Stroes ES, Hazen SL, van Miert JN, Kuivenhoven JA, et al. (2007) Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol 50: 159-165.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 159-165
    • Meuwese, M.C.1    Stroes, E.S.2    Hazen, S.L.3    van Miert, J.N.4    Kuivenhoven, J.A.5
  • 35
    • 0031453830 scopus 로고    scopus 로고
    • Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy
    • Horie K, Miyata T, Maeda K, Miyata S, Sugiyama S, et al. (1997) Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy. J Clin Invest 100: 2995-3004.
    • (1997) J Clin Invest , vol.100 , pp. 2995-3004
    • Horie, K.1    Miyata, T.2    Maeda, K.3    Miyata, S.4    Sugiyama, S.5
  • 36
    • 41949087380 scopus 로고    scopus 로고
    • Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury
    • Imai Y, Kuba K, Neely GG, Yaghubian-Malhami R, Perkmann T, et al. (2008) Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell 133: 235-249.
    • (2008) Cell , vol.133 , pp. 235-249
    • Imai, Y.1    Kuba, K.2    Neely, G.G.3    Yaghubian-Malhami, R.4    Perkmann, T.5
  • 37
    • 75349108481 scopus 로고    scopus 로고
    • Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: Effects on uptake of oxidized LDL in macrophages as a potential mechanism
    • de Faire U, Su J, Hua X, Frostegård A, Halldin M, et al. (2010) Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: Effects on uptake of oxidized LDL in macrophages as a potential mechanism. Journal of Autoimmunity 34: 73-79.
    • (2010) Journal of Autoimmunity , vol.34 , pp. 73-79
    • de Faire, U.1    Su, J.2    Hua, X.3    Frostegård, A.4    Halldin, M.5
  • 39
    • 84155172102 scopus 로고    scopus 로고
    • Immune-modulation by polyclonal IgM treatment reduces atherosclerosis in hypercholesterolemic apoE-/- mice
    • Cesena FHY, Dimayuga PC, Yano J, Zhao X, Kirzner J, et al. (2012) Immune-modulation by polyclonal IgM treatment reduces atherosclerosis in hypercholesterolemic apoE-/- mice. Atherosclerosis 220: 59-65.
    • (2012) Atherosclerosis , vol.220 , pp. 59-65
    • Cesena, F.H.Y.1    Dimayuga, P.C.2    Yano, J.3    Zhao, X.4    Kirzner, J.5
  • 41
    • 0032544110 scopus 로고    scopus 로고
    • Targeted gene disruption reveals a role for natural secretory IgM in the maturation of the primary immune response
    • Ehrenstein MR, O'Keefe TL, Davies SL, Neuberger MS, (1998) Targeted gene disruption reveals a role for natural secretory IgM in the maturation of the primary immune response. Proc Natl Acad Sci U S A 95: 10089-10093.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10089-10093
    • Ehrenstein, M.R.1    O'Keefe, T.L.2    Davies, S.L.3    Neuberger, M.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.