Serum anti-neuronal antibodies in amyotrophic lateral sclerosis

International Journal of Neuroscience

Volumn 123, Issue 8, 2013, Pages 557-562

  Çoban, Arzu ^a   Ulusoy, Canan ^b   Giriş, Murat ^b   Turan, Selin ^b   Türkoǧlu, Recai ^c   Tüzün, Erdem ^b   Idrisoǧlu, Halil Atilla ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c HAYDARPASA NUMUNE EDUCATION AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Amyotrophic lateral sclerosis; Anti neuronal antibodies; Serum

Indexed keywords

HU ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ARTICLE; AUTOIMMUNE ENCEPHALITIS; CENTRAL NERVOUS SYSTEM; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; ENCEPHALITIS; FEMALE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MOTOR NEURON DISEASE; NONHUMAN; RAT;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIBODIES; CASE-CONTROL STUDIES; FEMALE; GANGLIOSIDES; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; ION CHANNELS; MALE; MIDDLE AGED; NEURONS; RATS;

EID: 84880460838     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.3109/00207454.2013.782025     Document Type: Article

References (60)

1. Matsumoto H, Hanson MR, Chad DA. Amyotrophic lateral sclerosis. Recent advances in pathogenesis and therapeutic trials. Arch Neurol 1988;45(2):189-202 (Pubitemid 18054538)
2. Niebroj-Dobosz I, Jamrozik Z, Janik P, et al. Anti-neural antibodies in serum and cerebrospinal fluid of amyotrophic lateral sclerosis (ALS) patients. Acta Neurol Scand 1999;100(4):238-43 (Pubitemid 29428398)
3. Ikeda J, Kohriyama T, Nakamura S. Elevation of serum soluble E-selectin and antisulfoglucuronyl paragloboside antibodies in amyotrophic lateral sclerosis. Eur J Neurol 2000;7(5):541-7 (Pubitemid 32530116)
4. Yamazaki T, Suzuki M, Irie T, et al. Amyotrophic lateral sclerosis associated with IgG anti-GalNAc-GD1a antibodies. Clin Neurol Neurosurg 2008;110(7):722-4
5. Adams D, Kuntzer T, Burger D, et al. Predictive values of anti-GM1 ganglioside antibodies in neuromuscular diseases: A study of 180 sera. J Neuroimmunol 1991;32(3):223-30
6. Appel SH, Glenn Smith R, Engelhardt JI, Stefani E. Evidence for autoimmunity in amyotrophic lateral sclerosis. J Neurol Sci 1994;24(suppl):14-9
7. Drachman DB, Kuncl RW. Amyotrophic lateral sclerosis: An unconventional autoimmune disease? Ann Neurol 1989;26(2):269-74 (Pubitemid 19193097)
8. Kornberg AJ, Pestronk A. The clinical and diagnostic role of anti-GMI antibody testing. Muscle Nerve 1994;17(1):100-4 (Pubitemid 24012110)
9. Lamb NL, Patten BM. Clinical correlations of anti-GM1 antibodies in amyotrophic lateral sclerosis. Muscle Nerve 1991;14(10):1021-7
10. Haggiag S, Steiner-Birmanns B, Wirguin I, et al. Seroconversion of anti-GM1 antibodies in patients with amyotrophic lateral sclerosis. Neurology 2004;63(4):755-6 (Pubitemid 39100849)
11. Kornberg AJ. Anti-GM1 ganglioside antibodies: Their role in the diagnosis and pathogenesis of immune-mediatedmotor neuropathies. J Clin Neurosci 2000;7(3):191-4 (Pubitemid 30484974)
12. Niebroj-Dobosz I, Janik P, Kwieciñski H. Serum IgM anti-GM1 ganglioside antibodies in lower motor neuron syndromes. Eur J Neurol 2004;11(1):13-6 (Pubitemid 38174916)
13. Li F, Pestronk A. Autoantibodies to GM1 ganglioside: Different reactivity to GM1-Liposomes in amyotrophic lateral sclerosis and lower motor neuron disorders. J Neurol Sci 1991;104(2):209-14
14. Salazar-Grueso EF, Routbort MJ, Martin J, et al. Polyclonal IgM anti-GM1 ganglioside antibody in patients with motor neuron disease and variants. Ann Neurol 1990;27(5):558-63 (Pubitemid 20149978)
15. Stevens A,WellerM,Wiethölter H. A characteristic ganglioside antibody pattern in the CSF of patients with amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 1993;56(4):361-4 (Pubitemid 23120524)
16. Pestronk A, Adams RN, Cornblath D, et al. Patterns of serum IgM antibodies to GM1 and GD1a gangliosides in amyotrophic lateral sclerosis. Ann Neurol 1989;25(1):98-102 (Pubitemid 19032852)
17. Pestronk A, Adams RN, Clawson L, et al. Serum antibodies to GM1 ganglioside in amyotrophic lateral sclerosis. Neurology 1988;38(9):1457-61
18. Nwosu VK, Royer JA, Stickler DE. Voltage gated potassium channel antibodies in amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2010;11(4):392-4
19. Kimura F, Smith RG, Delbono O, et al. Amyotrophic lateral sclerosis patient antibodies label Ca2+ channel alpha 1 subunit. Ann Neurol 1994;35(2):164-71
20. Garcí Marti G, Perez Errazquin F, Chamorro Muñoz M, Romero Acebal M. Amyotrophic lateral sclerosis and anti-CV2 antibodies. Paraneoplastic association?. Neurologia 2007;22(6):406-9 (Pubitemid 47123015)
21. Brooks BR, Miller RG, Swash M, Munsat TL. El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1(5):293-9
22. Gallagher S, Winston SE, Fuller SA, Hurrell JG. Immunoblotting and immunodetection. Curr Protoc Cell Biol 2011;chap. 6:Unit 6.2
23. Pagani MR, Gonzalez LE, Uchitel OD. Autoimmunity in amyotrophic lateral sclerosis: Past and present. Neurol Res Int 2011;2011:1-11
24. Appel SH, Smith RG, Alexianu M, et al. Increased intracellular calcium triggered by immune mechanisms in amyotrophic lateral sclerosis. Clin Neurosci 1995;3(6): 368-74 (Pubitemid 27052171)
25. Appel SH, Engelhardt JI, Garcia J, Stefani E. Autoimmunity and ALS: A comparison of animal models of immunemediated motor neuron destruction and human ALS. Adv Neurol 1991;56:405-12
26. Haggstrom B, Andersen PM, Hjalmarsson K, et al. Autoimmunity and ALS: Studies on antibodies to acetylcholinesterase in sera. Acta Neurol Scand 1997;95(2):111-14 (Pubitemid 27107091)
27. Engelhardt JI, Appel SH. IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis. Arch Neurol 1990;47(11):1210-6 (Pubitemid 20381002)
28. Texidö L, Herńndez S, Martiá-Satué M, et al. Sera from amyotrophic lateral sclerosis patients induce the non-canonical activation of NMDA receptors "in vitro". Neurochem Int 2011;59(6):954-64
29. Freddo L, Yu RK, Latov N, et al. Gangliosides GM1 and GD1b are antigens for IgMM-proteins in a patient with motor neuron disease. Neurology 1986;36(4):454-8 (Pubitemid 16069997)
30. Pestronk A, Cornblath DR, Ilyas AA, et al. A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside. Ann Neurol 1988;24(1):73-8
31. Latov N, Hays AP, Donofrio PD, et al. Monoclonal IgM with unique specificity to gangliosides GM1 and GD1b and to lacto-N-Tetraose associated with human motor neuron disease. Neurology 1988;38(5):763-8
32. Nardelli E, Steck AJ, Barkas T, et al. Motor neuron syndrome and monoclonal IgM with antibody activity against gangliosides GM1 and GD1b. Ann Neurol 1988;23(5):524-8
33. Schluep M, Steck AJ. Immunostaining of motor nerve terminals by IgM M protein with activity against gangliosides GM1 andGD1b from a patient withmotor neuron disease. Neurology 1988;38(12):1890-2 (Pubitemid 19004587)
34. Shy ME, Evans VA, Lublin FD, et al. Antibodies to GM1 and GD1b in patients with motor neuron disease without plasma cell dyscrasia. Ann Neurol 1989;25(5):511-3 (Pubitemid 19136685)
35. Sadiq SA, Thomas FP, Kilidireas K, et al. The spectrumof neurologic disease associated with anti-GM1 antibodies. Neurology 1990;40(7):1067-72 (Pubitemid 20213973)
36. Sanders KA, Rowland LP, Murphy PL, et al. Motor neuron diseases and amyotrophic lateral sclerosis.GM1 antibodies and paraproteinemia. Neurology 1993;43(2):418-20 (Pubitemid 23060283)
37. Pestronk A, Chaudhry V, Feldman EL, et al. Lower motor neuron syndromes defined by patterns of weakness, nerve conduction abnormalities, and high titers of antiglycolipid antibodies. Ann Neurol 1990;27(3):316-26 (Pubitemid 20122384)
38. Kornberg AJ, Pestronk A, Bieser K, et al. The clinical correlates of high titer IgG anti-GM1 antibodies. Ann Neurol 1994;35(2):234-237 (Pubitemid 24050161)
39. Marcus DM, Latov N, Hsi BP, Gillard BK. Measurement and significance of antibodies against GM1 ganglioside. Report of a workshop, 18 April 1989, Chicago, IL, USA. J Neuroimmunol 1989;25(2-3):255-9 (Pubitemid 19276916)
40. Carpo M, Nobile-Orazio E, Meucci N, et al. Anti-GD1a ganglioside antibodies in peripheral motor syndromes. Ann Neurol 1996;39(4):539-43
41. O'Hanlon GM, Veitch J, Gallardo E, et al. Peripheral neuropathy associated with anti-GM2 ganglioside antibodies: Clinical and immunopathological studies. Autoimmunity 2000;32(2):133-44
42. Mizutani K, OkaN, Kusunoki S, et al. Amyotrophic lateral sclerosis with IgM antibody against gangliosides GM2 and GD2. Intern Med 2003;42(3):277-80 (Pubitemid 36519438)
43. Stich O, Kleer B, Rauer S. Absence of paraneoplastic antineuronal antibodies in sera of 145 patients with motor neuron disease. J Neurol Neurosurg Psychiatry 2007;78(8): 883-5 (Pubitemid 47204599)
44. Khwaja S, Sripathi N, Ahmad BK, Lennon VA. Paraneoplastic motor neuron disease with type 1 Purkinje cell antibodies. Muscle Nerve 1998;21(7):943-5 (Pubitemid 28262293)
45. Distad BJ, Weiss MD. Paraneoplastic motor neuron disease associated with Purkinje cell autoantibody type 1. J Clin Neuromuscul Dis 2010;12(1):36-41
46. Verma A, Berger JR, Snodgrass S, Petito C. Motor neuron disease: A paraneoplastic process associated with anti-hu antibody and small-cell lung carcinoma. Ann Neurol 1996;40(1): 112-6 (Pubitemid 26250150)
47. Forsyth PA, Dalmau J, Graus F, et al. Motor neuron syndromes in cancer patients. Ann Neurol 1997;41(6): 722-30 (Pubitemid 27249177)
48. Ogawa M, Nishie M, Kurahashi K, et al. Anti-Hu associated paraneoplastic sensory neuronopathy with upper motor neurone involvement. J Neurol Neurosurg Psychiatry 2004;75(7):1051-3 (Pubitemid 38869626)
49. Brown RH, Jr, Johnson D, Ogonowski M,Weiner HL. Antineural antibodies in the serum of patients with amyotrophic lateral sclerosis. Neurology 1987;37(1):152-5 (Pubitemid 17230126)
50. Kiernan JA, Hudson AJ. Anti-neurone antibodies are not characteristic of amyotrophic lateral sclerosis. Neuroreport 1993;4(4):427-30 (Pubitemid 23116740)
51. Vigliani MC, Polo P, Chi ò A, et al. Patients with amyotrophic lateral sclerosis and cancer do not differ clinically from patients with sporadic amyotrophic lateral sclerosis. J Neurol 2000;247(10):778-82
52. Vianello M, Vitaliani R, Pezzani R, et al. The spectrum of antineuronal autoantibodies in a series of neurological patients. J Neurol Sci 2004;220(1-2):29-36 (Pubitemid 38622094)
53. Greiner A, Schmausser B, Petzold K, et al. Neuronal targets of serum and cerebrospinal fluid autoantibodies in amyotrophic lateral sclerosis. Acta Neuropathol 1996;91(1):67-71
54. Irani SR, Alexander S, Waters P, et al. Antibodies to Kv1potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-Associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia. Brain 2010;133(9):2734-48
55. Rueff L, Graber JJ, Bernbaum M, Kuzniecky RI. Voltage-gated potassium channel antibody-mediated syndromes: A spectrum of clinical manifestations. Rev Neurol Dis 2008;5(2):65-72 (Pubitemid 351947617)
56. Lai M, Huijbers MG, Lancaster E, et al. Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: A case series. Lancet Neurol 2010;9(8):776-85
57. Lancaster E,HuijbersMG, Bar V, et al. Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia. Ann Neurol 2011;69(2):303-11
58. Dalmau J, Lancaster E, Martinez-Hernandez E, et al. Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis. Lancet Neurol 2011;10(1):63-74
59. Kürtüncü M, Kaya D, Zuliani L, et al. CACNA1H antibodies associated with headache with neurological deficits and cerebrospinal fluid lymphocytosis (HaNDL). Cephalalgia 2013;33(2):123-9
60. Vural B, Uǧurel E, Tüzün E, et al. Anti-neuronal and stressinduced-phosphoprotein 1 antibodies in neuro-Behc's disease. J Neuroimmunol 2011;239(1-2):91-7