Anti-GM1 ganglioside antibodies: Their role in the diagnosis and pathogenesis of immune-mediated motor neuropathies

Journal of Clinical Neuroscience

Volumn 7, Issue 3, 2000, Pages 191-194

  Kornberg, Andrew J ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GANGLIOSIDE ANTIBODY; GANGLIOSIDE GM1;

ANTIBODY BLOOD LEVEL; ATAXIA; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; HUMAN; MOTOR NEUROPATHY; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

EID: 0033916369     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1054/jocn.1999.0194     Document Type: Editorial

References (59)

1. A Pestronk D.R Cornblath A.A Ilyas A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside Ann Neurol 24 1988 73 78
2. E.L Feldman M.B Bromberg J.W Albers A Pestronk Immunosuppressive treatment in multifocal motor neuropathy Ann Neurol 30 1991 397 401
3. A Pestronk G Lopate A.J Kornberg Distal lower motor neuron syndrome with high titer serum IgM anti-GM1 antibodies: improvement following immunotherapy with monthly plasma exchange and intravenous cyclophosphamide Neurology 44 1994 2027 2031
4. R Kaji H Shibasaki J Kimura Multifocal demyelinating motor neuropathy: cranial nerve involvement and immunoglobulin therapy Neurology 42 1992 506 509
5. V Chaudhry A.M Corse D.R Cornblath Multifocal motor neuropathy: response to human immune globulin Ann Neurol 33 1993 237 242
6. E Nobile-Orazio N Meucci S Barbieri M Carpo G Scarlato High-dose intravenous immunoglobulin therapy in multifocal motor neuropathy Neurology 43 1993 537 544
7. A.J Kornberg A Pestronk Chronic motor neuropathies: diagnosis, therapy, and pathogenesis Ann Neurol 37(S1) 1995 S43 S50
8. A Pestronk V Chaudhry E.L Feldman Lower motor neuron syndromes defined by patterns of weakness, nerve conduction abnormalities, and high titers of antiglycolipid antibodies Ann Neurol 27 1990 316 326
9. A.J Kornberg A Pestronk The clinical and diagnostic role of anti-GM1 antibody testing Muscle Nerve 17 1994 100 104
10. P.A McCombe R Wilson R.L Prentice Results of testing for anti-GM1 antibodies J Clin Neurosci 1999
11. A Pestronk Invited review: motor neuropathies, motor neuron disorders, and antiglycolipid antibodies Muscle Nerve 14 1991 927 936
12. S.A Sadiq F.P Thomas K Kilidireas The spectrum of neurologic disease associated with anti-GM1 antibodies Neurology 40 1990 1067 1072
13. D Adams T Kuntzer D Burger Predictive value of anti-GM1 ganglioside antibodies in neuromuscular diseases: a study of 180 sera J Neuroimmunol 32 1991 223 230
14. N Yuki Molecular mimicry between gangliosides and lipopolysaccharides of Campylobacter jejuni isolated from patients with Guillain-Barré syndrome and Miller Fisher syndrome J Infect Dis 176(Suppl 2) 1997 S150 S153
15. R Kaji J Kimura Facts and fallacies on anti-GM1 antibodies: physiology of motor neuropathies Brain 122 1999 797 798
16. D.M Marcus N Latov B.P Hsi B.K Gillard Measurement and significance of antibodies against GM1 ganglioside. Report of a workshop, 18 April 1989, Chicago, IL, USA J Neuroimmunol 25 1989 255 259
17. A Pestronk A.J Kornberg The clinical correlates of IgG antiganglioside antibodies (a reply) Muscle Nerve 18 1995 1491 1492
18. F Li A Pestronk Autoantibodies to GM1 ganglioside: different reactivity to GM1-liposomes in amyotrophic lateral sclerosis and lower motor neuron disorders J Neurol Sci 104 1991 209 214
19. A Pestronk R.N Adams L Clawson Serum antibodies to GM1 ganglioside in amyotrophic lateral sclerosis Neurology 38 1988 1457 1461
20. A Pestronk R.N Adams D Cornblath R.W Kuncl D.B Drachman L Clawson Patterns of serum IgM antibodies to GM1 and GD1 a gangliosides in amyotrophic lateral sclerosis Ann Neurol 25 1989 98 102
21. M Monestier B.L Kotzin Antibodies to histones in systemic lupus erythematosus and drug-induced lupus syndromes Rheum Dis Clin North Am 18 1992 415 436
22. A Pestronk F Li K Bieser Anti-MAG antibodies: major effects of antigen purity and antibody cross-reactivity on ELISA results and clinical correlation Neurology 44 1994 1131 1137
23. A Pestronk R Choksi G Blume G Lopate Multifocal motor neuropathy: serum IgM binding to a GM1 ganglioside-containing lipid mixture but not to GM1 alone Neurology 48 1997 1104 1106
24. A Pestronk R Choksi Multifocal motor neuropathy. Serum IgM anti-GM1 ganglioside antibodies in most patients detected using covalent linkage of GM1 to ELISA plates Neurology 49 1997 1289 1292
25. A.J Kornberg A Pestronk K Bieser The clinical correlates of high titer IgG anti-GM1 antibodies Ann Neurol 35 1994 234 237
26. A.J Kornberg A Pestronk G.M Blume G Lopate J Yue A Hahn Selective staining of the cerebellar molecular layer by serum IgG in Miller-Fisher and related syndromes Neurology 47 1996 1317 1320
27. A Chiba S Kusunoki T Shimizu I Kanazawa Serum IgG antibody to ganglioside GQ 1b is a possible marker of Miller Fisher syndrome Ann Neurol 31 1992 677 679
28. Q1bantibody in Fisher’s syndrome Neurology 43 1993 414 417
29. B Buchwald K.V Toyka J Zielasek A Weishaupt S Schweiger J Dudel Neuromuscular blockade by IgG antibodies from patients with Guillain-Barré syndrome: a macro-patch-clamp study Ann Neurol 44 1998 913 922
30. G Lopate A Pestronk A.J Kornberg J Yue R Choksi IgM anti-sulfatide autoantibodies: patterns of binding to cerebellum, dorsal root ganglion and peripheral nerve J Neurol Sci 151 1997 189 193
31. A Pestronk F Li J Griffin Polyneuropathy syndromes associated with serum antibodies to sulfatide and myelin-associated glycoprotein Neurology 41 1991 357 362
32. A Pestronk K Bieser R Choksi A Whitton A Kornberg W-C Yee Anti-MAG antibodies: major effects of antigen purity and antibody cross-reactivity on ELISA results and clinical correlation Neurology 44(Suppl 2) 1994
33. B Chassande J-M Legér A.B Younes-Chennoufi Peripheral neuropathy associated with IgM monoclonal gammopathy: correlations between M-protein antibody activity and clinical/electrophysiological features in 40 cases Muscle Nerve 21 1998 55 62
34. G Lopate A Kornberg R Choksi A Pestronk Anti-MAG and anti-sulfatide antibodies: variability in tissue staining patterns and correlation with ELISA binding to non-hydroxylated sulfatide Muscle Nerve Supplement 7 1998
35. A.H Ropper K.C Gorson Neuropathies associated with paraproteinemia N Engl J Med 338 1998 1601 1607
36. 3gangliosides Neurology 44 1994 2395 2397
37. M.C Dalakas R.H Quarles Autoimmune ataxic neuropathies (sensory ganglionopathies): are glycolipids the responsible autoantigens? Ann Neurol 39 1996 419 422
38. S Kusunoki H Mashiko N Mochizuki Binding of antibodies against GM1 and GD1b in human peripheral nerve Muscle Nerve 20 1997 840 845
39. L Freddo R.K Yu N Latov Gangliosides GM1 and GD1b are antigens for IgM M-protein in a patient with motor neuron disease Neurology 36 1986 454 458
40. H.J Willison P.G.E Kennedy Gangliosides and bacterial toxins in Guillain-Barré syndrome J Neuroimmunol 46 1993 105 112
41. M Santoro F.P Thomas M.E Fink IgM deposits at nodes of Ranvier in a patient with amyotrophic lateral sclerosis, anti-GM1 antibodies, and multifocal motor conduction block Ann Neurol 28 1990 373 377
42. M Corbo A Quattrini N Latov A.P Hays Localization of GM1 and Gal(b1–3)GalNAc antigenic determinants in peripheral nerve Neurology 43 1993 809 814
43. M Corbo A Quattrini A Lugaresi M Santoro N Latov A.P Hays Patterns of reactivity of human anti-GM1 antibodies with spinal cord and motor neurons Ann Neurol 32 1992 487 493
44. D.J Lange W Trojaborg Do GM1 antibodies induce demyelination? Muscle Nerve 17 1994 105 107
45. A Uncini M Santoro M Corbo A Lugaresi N Latov Conduction abnormalities induced by sera of patients with multifocal motor neuropathy and anti-GM1 antibodies Muscle Nerve 16 1993 610 615
46. N Latov Neuropathy and anti-GM1 antibodies Ann Neurol 27(suppl) 1990 S41 S43
47. F.P Thomas J.E Thomas S.A Sadiq Human monoclonal IgM anti-Gal(b1–3) GalNAc autoantibodies bind to the surface of bovine spinal motoneurons J Neuropathol Exp Neurol 49 1990 89 95
48. F.P Thomas W Trojaborg C Nagy Experimental autoimmune neuropathy with anti-GM1 antibodies and immunoglobulin deposits at the nodes of Ranvier Acta Neuropathol 82 1991 378 383
49. H Baba G.C Daune A.A Ilyas Anti-GM1 ganglioside antibodies with differing fine specificities in patients with multifocal motor neuropathy J Neuroimmunol 25 1989 143 150
50. K Arasaki S Kusunoki N Kudo I Kanazawa Acute conduction block in vitro following exposure to antiganglioside sera Muscle Nerve 16 1993 587 593
51. H.J Willison G Paterson P.G.E Kennedy J Veitch Cloning of human anti-GM1 antibodies from motor neuropathy patients Ann Neurol 35 1994 471 478
52. K Ogawa-Goto N Funamoto T Abe K Nagashima Different ceramide compositions of gangliosides between human motor and sensory nerves J Neurochem 55 1990 1486 1493
53. K Ogawa-Goto N Funamoto Y Ohta T Abe K Nagashima Myelin gangliosides of human peripheral nervous system: an enrichment of GM1 in the motor nerve myelin isolated from cauda equina J Neurochem 59 1992 1844 1849
54. S.G Waxman J.M Ritchie Molecular dissection of the myelinated axon Ann Neurol 33 1993 121 136
55. S.G Waxman Sodium channel blockade by antibodies: a new mechanism of neurological disease? Ann Neurol 37 1995 421 423
56. +currents in isolated rat myelinated nerve fibers Ann Neurol 37 1995 436 442
57. N Hirota R Kaji H Bostock The physiological effect of anti-GM1 antibodies on saltatory conduction and transmembrane currents in single motor axons Brain 120 1997 2159 2169
58. K.A Sheikh T.J Deerinck M.H Ellisman J.W Griffin The distribution of ganglioside-like moieties in peripheral nerve Brain 122 1999 449 460
59. K Paparounas G O’Hanlon C O’Leary E Rowan H Willison Anti-ganglioside antibodies can bind peripheral nerve nodes of Ranvier and activate the complement cascade without inducing acute conduction block in vitro Brain 122 1999 807 816