Paraventricular NUCB2/nesfatin-1 rises in synchrony with feeding suppression during early light phase in rats

Biochemical and Biophysical Research Communications

Volumn 434, Issue 3, 2013, Pages 434-438

  Sedbazar, Udval ^a   Maejima, Yuko ^a   Nakata, Masanori ^a   Mori, Masatomo ^b   Yada, Toshihiko ^a,c  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

Diurnal rhythm; Feeding; Nesfatin 1; NUCB2; Obesity; Paraventricular nucleus

Indexed keywords

IMMUNOGLOBULIN G; MESSENGER RNA; NESFATIN 1; NEUROPEPTIDE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; DNA BINDING PROTEIN; NERVE PROTEIN; NUCLEOBINDIN; PRIMER DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVE; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENERGY BALANCE; FEEDING; FOOD INTAKE; GENE EXPRESSION; HOMEOSTASIS; HORMONE RELEASE; HYPERPHAGIA; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; ZUCKER FATTY RAT; ANIMAL; FEEDING BEHAVIOR; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT;

RATTUS;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; DNA PRIMERS; DNA-BINDING PROTEINS; FEEDING BEHAVIOR; MALE; NERVE TISSUE PROTEINS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MLCS; MLOWN;

EID: 84880452708     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.03.090     Document Type: Article

References (19)

1. S. Oh-I, H. Shimizu, T. Satoh, et al., Identification of nesfatin-1 as a satiety molecule in the hypothalamus, Nature 443 (2006) 709-712.
2. Y. Maejima, U. Sedbazar, S. Suyama, et al., Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway, Cell Metab. 10 (2009) 355-365.
3. D. Kohno, M. Nakata, Y. Maejima, et al., Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding, Endocrinology 149 (2008) 1295-1301.
4. S.F. Leibowitz, N.J. Hammer, K. Chang, Hypothalamic paraventricular nucleus lesions produce overeating and obesity in the rat, Physiol. Behav. 27 (1981) 1031-1040.
5. M.W. Schwartz, S.C. Woods, D. Porte Jr., Central nervous system control of food intake, Nature 404 (2000) 661-671.
6. E. Badoer, Role of the hypothalamic PVN in the regulation of renal sympathetic nerve activity and blood flow during hyperthermia and in heart failure, Am. J. Physiol. Renal Physiol. 298 (2010) F839-F846.
7. A.V. Furguson, K.V. Latchford, W.K. Samson, The paraventricular nucleus of the hypothalamus a potential target for integrative treatment of autonomic dysfunction, Expert Opin. Ther. Targets 12 (2008) 717-727.
8. E. Tousson, H. Meissl, Suprachiasmatic nuclei grafts restore the circadian rhythm in the paraventricular nucleus of the hypothalamus, J. Neurosci. 24 (2004) 2983-2988.
9. A. Kalsbeek, E. Flier, M.A. Hofman, et al., Vasopressin and output of hypothalamic biological clock, J. Neuroendocrionol. 22 (2010) 362-372.
10. C. Guilding, A.T. Hughes, T.M. Brown, et al., A riot of rhythms: neuronal and glial circadian oscillators in the mediobasal hypothalamus, Mol. Brain 2 (2009) 28-45.
11. G. Zhang, D. Cai, Circadian intervention of obesity development via resting-stage feeding manipulation or oxytocin treatment, Am. J. Physiol. Endocrinol. Metab. 301 (2011) E1004-E1012.
12. F.W. Turek, C. Joshu, A. Kohsaka, et al., Obesity and metabolic syndrome in circadian clock mutant mice, Science 5724 (2005) 1043-1045.
13. D.M. Arble, J. Bass, A.D. Laposky, et al., Circadian timing of food intake contributes to weight gain, Obesity (Silver Spring) 17 (2009) 2100-2102.
14. R. Salgado-Delgado, M. Angeles-Castellanos, N. Saderi, et al., Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work, Endocrinology 151 (2010) 1019-1029.
15. M. Hatori, C. Vollmers, A. Zarrinpar, et al., Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet, Cell Metab. 15 (2012) 848-860.
16. T. Yamashita, T. Murakami, M. Iida, et al., Leptin receptor of Zucker fatty rat performs reduced signal transduction, Diabetes 46 (1997) 1077-1080.
17. P.J. Wangsness, B.A. Dilettuso, R.J. Martin, Dietary effects on body weight, feed intake and diurnal feeding behavior of genetically obese rats, J. Nutr. 108 (1978) 256-264.
18. A. Kalsbeek, R. Teclemariam-Mesbah, P. Pévet, Efferent projections of the suprachiasmatic nucleus in the golden hamster (Mesocricetus auratus), J. Comp. Neurol. 332 (1993) 293-314.
19. 2+ signaling in nesfatin-1 neurons in the hypothalamic paraventricular nucleus, Biochem. Biophys. Res. Commun. 420 (2012) 811-815.