The incidence and magnitude of fibrinolytic activation in trauma patients: A reply to a rebuttal

Journal of Thrombosis and Haemostasis

Volumn 11, Issue 7, 2013, Pages 1437-1438

  Hunt, B J ^a   Raza, I ^b   Brohi, K ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFIBRINOLYTIC AGENT; CALCIUM CHLORIDE; PLASMIN; TRANEXAMIC ACID;

ACIDIFICATION; ARTERY THROMBOSIS; BLEEDING; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; DRUG EFFICACY; DRUG SAFETY; EARLY INTERVENTION; EUGLOBULIN LYSIS TEST; FIBRINOLYSIS; HUMAN; HYPERFIBRINOLYSIS; INJURY; INJURY SEVERITY; LETTER; MORTALITY; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; RISK FACTOR; RISK REDUCTION; THERAPY DELAY; THROMBOELASTOGRAPHY;

BLOOD COAGULATION DISORDERS; FEMALE; FIBRINOLYSIS; HUMANS; MALE; WOUNDS AND INJURIES;

EID: 84880445853     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12296     Document Type: Letter

References (5)

1. Ramos CR, Moore EE, Manco-Johnson ML, Silliman CC, Chapman MC, Banerjee A. Diagnosis of hyperfibrinolysis in trauma requires further validation. J Thromb Haemost 2013; 11: 307-14. http://dx.doi.org/10.1111/jth.12240
2. Shakur H, Roberts I, Bautista R, Caballero J, Coats T, Dewan Y, El-Sayed H, Gogichaishvili T, Gupta S, Herrera J, Hunt B, Iribhogbe P, Izurieta M, Khamis H, Komolafe E, Marrero M-A, Mejía-Mantilla J, Miranda J, Morales C, Olaomi O, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010 376 23-32 http://www.ncbi.nlm.nih.gov/pubmed/20554319
3. Roberts I, Perel P, Prieto-Merino D, Shakur H, Coats T, Hunt BJ, Lecky F, Brohi K, Willett K. Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial. BMJ 2012 345: e5839. http://www.bmj.com/cgi/doi/10.1136/bmj.e5839
4. Roberts I, Shakur H, Afolabi A, Brohi K, Coats T, Dewan Y, Gando S, Guyatt G, Hunt BJ, Morales C, Perel P, Prieto-Merino D, Woolley T. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet 2011 377: 1096-101. http://www.ncbi.nlm.nih.gov/pubmed/21439633
5. Katz J, Lurie A, Becker D, Metz J. The euglobulin lysis time test: an ineffectual monitor of the therapeutic inhibition of fibrinolysis. J Clin Pathol 1970; 23: 529-32.