Label-free, high-throughput, electrical detection of cells in droplets

Analyst

Volumn 138, Issue 16, 2013, Pages 4585-4592

  Kemna, Evelien W M ^a   Segerink, Loes I ^a   Wolbers, Floor ^a   Vermes, István ^a   Van Den Berg, Albert ^a  

^a UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84880435145     PISSN: 00032654     EISSN: 13645528     Source Type: Journal    
DOI: 10.1039/c3an00569k     Document Type: Article

References (27)

1. D. A. Weitz et al., Drop-based microfluidic devices for encapsulation of single cells Lab Chip 2008 8 7 1110 1115
2. E. Um S. G. Lee J. K. Park Random breakup of microdroplets for single-cell encapsulation Appl. Phys. Lett. 2010 97 15 153703-1 153703-3
3. A. A. Bhagat et al., Inertial microfluidics for sheath-less high-throughput flow cytometry Biomed. Microdevices 2010 12 2 187 195
4. J. F. Edd et al., Controlled encapsulation of single-cells into monodisperse picolitre drops Lab Chip 2008 8 8 1262 1264
5. S. Koster et al., Drop-based microfluidic devices for encapsulation of single cells Lab Chip 2008 8 7 1110 1115
6. G. Gelinck et al., Charge transport in high-performance ink-jet printed single-droplet organic transistors based on a silylethynyl substituted pentacene/insulating polymer blend Org. Electron. 2011 12 8 1319 1327
7. S. H. Chao et al., Real-time PCR of single bacterial cells on an array of adhering droplets Lab Chip 2011 11 13 2276 2281
8. A. R. Wheeler et al., Digital microfluidics with in-line sample purification for proteomics analyses with MALDI-MS Anal. Chem. 2005 77 2 534 540
9. P. Koltay et al., Inkjet-like printing of single-cells Lab Chip 2011 11 14 2447 2454
10. J. Clausell-Tormos et al., Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms Chem. Biol. 2008 15 5 427 437
11. E. Brouzes et al., Droplet microfluidic technology for single-cell high-throughput screening Proc. Natl. Acad. Sci. U. S. A. 2009 106 34 14195 14200
12. E. W. Kemna et al., High-yield cell ordering and deterministic cell-in-droplet encapsulation using Dean flow in a curved microchannel Lab Chip 2012 12 16 2881 2887
13. S. K. Y. Tang et al., A multi-color fast-switching microfluidic droplet dye laser Lab Chip 2009 9 19 2767 2771
14. L. I. Segerink et al., On-chip determination of spermatozoa concentration using electrical impedance measurements Lab Chip 2010 10 8 1018 1024
15. N. Bao J. Wang C. Lu Recent advances in electric analysis of cells in microfluidic systems Anal. Bioanal. Chem. 2008 391 3 933 942
16. R. Lin et al., Novel on-demand droplet generation for selective fluid sample extraction Biomicrofluidics 2012 6 2 024103-1 024103-10
17. D. Holmes et al., Leukocyte analysis and differentiation using high speed microfluidic single cell impedance cytometry Lab Chip 2009 9 20 2881 2889
18. D. Holmes H. Morgan Single cell impedance cytometry for identification and counting of CD4 T-cells in human blood using impedance labels Anal. Chem. 2010 82 4 1455 1461
19. P. G. Steenbakkers H. A. Hubers A. W. Rijnders Efficient generation of monoclonal antibodies from preselected antigen-specific B cells. Efficient immortalization of preselected B cells Mol. Biol. Rep. 1994 19 2 125 134
20. H. Morgan et al., High speed multi-frequency impedance analysis of single particles in a microfluidic cytometer using maximum length sequences Lab Chip 2007 7 8 1034 1040
21. K. R. Foster H. P. Schwan Dielectric-Properties of Tissues and Biological-Materials-a Critical-Review CRC Crit. Rev. Bioeng. 1989 17 1 25 104
22. T. Sun H. Morgan Single-cell microfluidic impedance cytometry: a review Microfluid. Nanofluid. 2010 8 4 423 443
23. J. C. Maxwell, A treatise on electricity and magnetism, Clarendon press, Oxford, 1873
24. A. B. Cosimi et al., Immunologic monitoring with monoclonal antibodies to human T-cell subsets Transplant. Proc. 1981 13 3 1589 1593
25. W. P. Carney et al., Analysis of T lymphocyte subsets in cytomegalovirus mononucleosis J. Immunol. 1981 126 6 2114 2116
26. G. R. Langereis, An integrated sensor system for monitoring washing processes, University of Twente, 1999
27. S. Archer et al., Cell reactions to dielectrophoretic manipulation Biochem. Biophys. Res. Commun. 1999 257 3 687 698