Molecular epidemiology of integron-associated antimicrobial gene cassettes in the clinical isolates of acinetobacter baumannii from northern taiwan

Annals of Laboratory Medicine

Volumn 33, Issue 4, 2013, Pages 242-247

  Lin, Ming Feng ^a,b   Liou, Ming Li ^c,d   Tu, Chi Chao ^a,d   Yeh, Hui Wen ^a   Lan, Chung Yu ^b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^c PROVIDENCE UNIVERSITY   (Taiwan)

^d YUANPEI UNIVERSITY   (Taiwan)

Author keywords

Acinetobacter baumannii; Antimicrobial; Integron

Indexed keywords

EID: 84880395182     PISSN: 22343806     EISSN: 22343814     Source Type: Journal    
DOI: 10.3343/alm.2013.33.4.242     Document Type: Article

References (29)

1. Perez F, Hujer AM, Hujer KM, Decker BK, Rather PN, Bonomo RA. Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother 2007;51:3471-84.
2. Peleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 2008;21:538-82.
3. Valenzuela JK, Thomas L, Partridge SR, van der Reijden T, Dijkshoorn L, Iredell J. Horizontal gene transfer in a polyclonal outbreak of carbapenem-resistant Acinetobacter baumannii. J Clin Microbiol 2007;45:453-60.
4. Carattoli A. Importance of integrons in the diffusion of resistance. Vet Res 2001;32:243-59.
5. Mazel D. Integrons: agents of bacterial evolution. Nat Rev Microbiol 2006;4:608-20.
6. Gu B, Tong M, Zhao W, Liu G, Ning M, Pan S, et al. Prevalence and characterization of class I integrons among Pseudomonas aeruginosa and Acinetobacter baumannii isolates from patients in Nanjing, China. J Clin Microbiol 2007;45:241-3.
7. Huang LY, Chen TL, Lu PL, Tsai CA, Cho WL, Chang FY, et al. Dissemination of multidrug-resistant, class 1 integron-carrying Acinetobacter baumannii isolates in Taiwan. Clin Microbiol Infect 2008;14:1010-9.
8. Turton JF, Kaufmann ME, Glover J, Coelho JM, Warner M, Pike R, et al. Detection and typing of integrons in epidemic strains of Acinetobacter baumannii found in the United Kingdom. J Clin Microbiol 2005;43:3074-82.
9. Chen TL, Siu LK, Wu RC, Shaio MF, Huang LY, Fung CP, et al. Comparison of one-tube multiplex PCR, automated ribotyping and intergenic spacer (ITS) sequencing for rapid identification of Acinetobacter baumannii. Clin Microbiol Infect 2007;13:801-6.
10. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Disk Susceptibility Tests. Approved Standards-Tenth edition, M02-A10. Wayne, PA: Clinical and Laboratory Standards Institute, 2009.
11. Koeleman JG, Stoof J, Van Der Bijl MW, Vandenbroucke-Grauls CM, Savelkoul PH. Identification of epidemic strains of Acinetobacter baumannii by integrase gene PCR. J Clin Microbiol 2001;39:8-13.
12. Vincze T, Posfai J, Roberts, R.J. NEBcutter: a program to cleave DNA with restriction enzymes. Nucleic Acids Res 2003;31:3688-91.
13. Misbah S, AbuBakar S, Hassan H, Hanifah YA, Yusof MY. Antibiotic susceptibility and REP-PCR fingerprints of Acinetobacter spp. isolated from a hospital ten years apart. J Hosp Infect 2004;58:254-61.
14. Gaur A, Prakash P, Anupurba S, Mohapatra TM. Possible role of integrase gene polymerase chain reaction as an epidemiological marker: study of multidrug-resistant Acinetobacter baumannii isolated from nosocomial infections. Int J Antimicrob Agents 2007;29:446-50.
15. Gallego L and Towner KJ. Carriage of class 1 integrons and antibiotic resistance in clinical isolates of Acinetobacter baumannii from northern Spain. J Med Microbiol 2001;50:71-7.
16. Gombac F, Riccio ML, Rossolini GM, Lagatolla C, Tonin E, Monti-Bragadin C, et al. Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian hospitals reveals a limited diversity of gene cassette arrays. Antimicrob Agents Chemother 2002;46:3665-8.
17. Sung JY, Kwon KC, Cho HH, Koo SH. Antimicrobial resistance determinants in imipenem-nonsusceptible Acinetobacter calcoaceticus-baumannii complex isolated in Daejeon, Korea. Korean J Lab Med 2011;31: 265-70.
18. Seifert H, Dolzani L, Bressan R, van der Reijden T, van Strijen B, Stefanik D, et al. Standardization and interlaboratory reproducibility assessment of pulsed-field gel electrophoresis-generated fingerprints of Acinetobacter baumannii. J Clin Microbiol 2005;43:4328-35.
19. Bartual SG, Seifert H, Hippler C, Luzon MA, Wisplinghoff H, Rodríguez-Valera F. Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii. J Clin Microbiol 2005;43:4382-90.
20. Higgins PG, Hujer AM, Hujer KM, Bonomo RA, Seifert H. Interlaboratory reproducibility of DiversiLab rep-PCR typing and clustering of Acinetobacter baumannii isolates. J Med Microbiol 2012;61:137-41.
21. Higgins PG, Janssen K, Fresen MM, Wisplinghoff H, Seifert H. Molecular epidemiology of Acinetobacter baumannii bloodstream isolates obtained in the United States from 1995 to 2004 using rep-PCR and multilocus sequence typing. J Clin Microbiol 2012;50:3493-500.
22. Lin MF, Chang KC, Yang CY, Yang CM, Xiao CC, Kuo HY, et al. Role of integrons in antimicrobial susceptibility patterns of Acinetobacter baumannii. Jpn J Infect Dis 2010;63:440-3.
23. Zhong Q, Xu W, Wu Y, Xu H. Clonal spread of carbapenem non-susceptible Acinetobacter baumannii in an intensive care unit in a teaching hospital in China. Ann Lab Med 2012;32:413-9.
24. Nemec A, Dolzani L, Brisse S, van den Broek P, Dijkshoorn L. Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones. J Med Microbiol 2004;53:1233-40.
25. Lee YT, Huang LY, Chen TL, Siu LK, Fung CP, Cho WL, et al. Gene cassette arrays, antibiotic susceptibilities, and clinical characteristics of Acinetobacter baumannii bacteremic strains harboring class 1 integrons. J Microbiol Immunol Infect 2009;42:210-9.
26. Su CH, Wang JT, Hsiung CA, Chien LJ, Chi CL, Yu HT, et al. Increase of carbapenem-resistant Acinetobacter baumannii infection in acute care hospitals in Taiwan: association with hospital antimicrobial usage. PLoS One 2012;7:e37788.
27. Chen YS, Lin HH, Wu CH, Hsiao YS, Hsu NS, Chen YL. Colonization of a medical center in Southern Taiwan by epidemic strains of carbapenem-and multidrug-resistant Acinetobacter baumannii and the genetic organization of their integrons. Jpn J Infect Dis 2009;62:155-7.
28. Lin MF, Chang KC, Lan CY, Chou JL, Kuo JW, Chang CK, et al. Molecular epidemiology and antimicrobial resistance determinants of multidrugresistant Acinetobacter baumannii among five proximal hospitals in Taiwan. Jpn J Infect Dis 2011;64:222-7.
29. Iacono M, Villa L, Fortini D, Bordoni R, Imperi F, Bonnal RJ, et al. Wholegenome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group. Antimicrob Agents Chemother 2008;52:2616-25.