Effects of fluvastatin on the pharmacokinetics of repaglinide: Possible role of CYP3A4 and P-glycoprotein inhibition by fluvastatin

Korean Journal of Physiology and Pharmacology

Volumn 17, Issue 3, 2013, Pages 245-251

  Lee, Chong Ki ^a   Choi, Jun Shik ^b   Bang, Joon Seok ^b  

^a Chodang University   (South Korea)

^b Chosun University   (South Korea)

Author keywords

Bioavailability; CYP3A4; Fluvastatin; P glycoprotein; Repaglinide

Indexed keywords

CYTOCHROME P450 3A4; FLUINDOSTATIN; GLUCOSE; MULTIDRUG RESISTANCE PROTEIN; REPAGLINIDE; RHODAMINE 123;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFECT; DRUG HALF LIFE; DRUG INHIBITION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHARMACOKINETICS; PLASMA CONCENTRATION-TIME CURVE; RAT; SMALL INTESTINE; TIME TO MAXIMUM PLASMA CONCENTRATION;

EID: 84880390454     PISSN: 12264512     EISSN: 20933827     Source Type: Journal    
DOI: 10.4196/kjpp.2013.17.3.245     Document Type: Article

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