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Volumn 111, Issue , 2013, Pages 384-391
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The effect of pH and ionic strength of dissolution media on in-vitro release of two model drugs of different solubilities from HPMC matrices
b
Colorcon Ltd
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(United Kingdom)
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Author keywords
Diltiazem HCl; HPMC polymeric matrix tablets; Hydration; Hydrochlorothiazide; Ionic strength; Kinetics of drug release; Similarity factor
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Indexed keywords
DILTIAZEM;
DRUG RELEASE;
HYDROCHLOROTHIAZIDE;
POLYMERIC MATRICES;
SIMILARITY FACTORS;
DISSOLUTION;
HYDRATION;
HYDROPHILICITY;
PH EFFECTS;
POLYMERS;
IONIC STRENGTH;
DILTIAZEM;
HYDROCHLOROTHIAZIDE;
HYDROXYPROPYLMETHYLCELLULOSE;
POLYMER;
SODIUM CHLORIDE;
WATER;
DELAYED RELEASE FORMULATION;
ARTICLE;
CONTROLLED DRUG RELEASE;
CONTROLLED STUDY;
DIFFERENTIAL SCANNING CALORIMETRY;
DISSOLUTION;
DRUG SOLUBILITY;
GEL;
HYDRATION;
HYDROPHILICITY;
IN VITRO STUDY;
IONIC STRENGTH;
MATRIX TABLET;
PH;
PREDICTION;
PRIORITY JOURNAL;
SIMULATION;
TABLET COMPRESSION;
TABLET POROSITY;
TREND STUDY;
WATER PERMEABILITY;
CHEMISTRY;
DELAYED RELEASE FORMULATION;
OSMOLARITY;
SOLUBILITY;
CALORIMETRY, DIFFERENTIAL SCANNING;
DELAYED-ACTION PREPARATIONS;
DILTIAZEM;
HYDROCHLOROTHIAZIDE;
HYDROGEN-ION CONCENTRATION;
HYPROMELLOSE DERIVATIVES;
OSMOLAR CONCENTRATION;
SOLUBILITY;
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EID: 84880370482
PISSN: 09277765
EISSN: 18734367
Source Type: Journal
DOI: 10.1016/j.colsurfb.2013.06.034 Document Type: Article |
Times cited : (62)
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References (29)
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