Meta-analysis of associations of the ezrin gene with human osteosarcoma response to chemotherapy and prognosis

Asian Pacific Journal of Cancer Prevention

Volumn 14, Issue 5, 2013, Pages 2753-2758

  Wang, Zhe ^a   He, Mao Lin ^a   Zhao, Jin Min ^a   Qing, Hai Hui ^a   Wu, Yang ^a  

^a FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Chemotherapy; Ezrin; Meta analysis; Osteosarcoma; Survival

Indexed keywords

CYTOSKELETON PROTEIN; EZRIN; TUMOR MARKER;

BIOSYNTHESIS; BONE NEOPLASMS; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; HUMAN; META ANALYSIS; MORTALITY; OSTEOSARCOMA; PATHOLOGY; RECEIVER OPERATING CHARACTERISTIC; RISK; SURVIVAL RATE; TREATMENT OUTCOME;

BONE NEOPLASMS; CYTOSKELETAL PROTEINS; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ODDS RATIO; OSTEOSARCOMA; ROC CURVE; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 84880347584     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2013.14.5.2753     Document Type: Article

References (37)

1. Bal N, Yildirim S, Nursal TZ, Bolat F, Kayaselcuk F (2007). Association of ezrin expression in intestinal and diffuse gastric carcinoma with clinicopathological parameters and tumor type. World J Gastroenterol, 13, 3726-9.
2. Boldrini E, Peres SV, Morini S, de Camargo B (2010). Immunoexpression of Ezrin and CD44 in patients with osteosarcoma. J Pediatr Hematol Oncol, 32, e213-7.
3. Brambilla D, Fais S (2009). The Janus-faced role of ezrin in "linking" cells to either normal or metastatic phenotype. Int J Cancer, 125, 2239-45.
4. Bretscher A, Edwards K, Fehon RG (2002). ERM proteins and merlin: integrators at the cell cortex. Nat Rev Mol Cell Biol, 3, 586-99.
5. Elliott BE, Meens JA, SenGupta SK, Louvard D, Arpin M (2005). The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells. Breast Cancer Res, 7, R365-73.
6. Federici C, Brambilla D, Lozupone F, et al (2009). Pleiotropic function of ezrin in human metastatic melanomas. Int J Cancer, 124, 2804-12.
7. Foster L, Dall GF, Reid R, Wallace WH, Porter DE (2007). Twentieth-century survival from osteosarcoma in childhood. Trends from 1933 to 2004. J Bone Joint Surg Br, 89, 1234-8.
8. Gautreau A, Poullet P, Louvard D, Arpin M (1999). Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci U S A, 96, 7300-5.
9. Gorlick R (2009). Current concepts on the molecular biology of osteosarcoma. Cancer Treat Res, 152, 467-78.
10. Hong-Jian W, Cheng-Zhang S, Xian-Feng Q, Qiu-Shi H (2007). Expression of ezrin, E-cadherin and focal adhesion kinase in colorectal carcinoma and their clinical significances. World Chin J Digestol, 15, 5.
11. Hunter KW (2004). Ezrin, a key component in tumor metastasis. Trends Mol Med, 10, 201-4.
12. Khanna C, Wan X, Bose S, et al (2004). The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis. Nat Med, 10, 182-6.
13. Kim C, Shin E, Hong S, et al (2009). Clinical value of ezrin expression in primary osteosarcoma. Cancer Res Treat, 41, 138-44.
14. Kim MS, Song WS, Cho WH, Lee SY, Jeon DG (2007). Ezrin expression predicts survival in stage IIB osteosarcomas. Clin Orthop Relat Res, 459, 229-36.
15. Krishnan K, Bruce B, Hewitt S, et al (2006). Ezrin mediates growth and survival in Ewing's sarcoma through the AKT/mTOR, but not the MAPK, signaling pathway. Clin Exp Metastasis, 23, 227-36.
16. Kumar R, Wang RA, Bagheri-Yarmand R (2003). Emerging roles of MTA family members in human cancers. Semin Oncol, 30, 30-7.
17. Lau J, Ioannidis JP, Schmid CH (1997). Quantitative synthesis in systematic reviews. Ann Intern Med, 127, 820-6.
18. Li YG, Geng X (2010). A meta-analysis on the association of HER-2 overexpression with prognosis in human osteosarcoma. Eur J Cancer Care (Engl), 19, 313-6.
19. Martin TA, Harrison G, Mansel RE, Jiang WG (2003). The role of the CD44/ezrin complex in cancer metastasis. Crit Rev Oncol Hematol, 46, 165-86.
20. McClatchey AI (2003). Merlin and ERM proteins: unappreciated roles in cancer development. Nat Rev Cancer, 3, 877-83.
21. Moses LE, Shapiro D, Littenberg B (1993). Combining independent studies of a diagnostic test into a summary ROC curve: dataanalytic approaches and some additional considerations. Stat Med, 12, 1293-316.
22. Ottaviani G, Jaffe N (2009). The etiology of osteosarcoma. Cancer Treat Res, 152, 15-32.
23. Pakos EE, Ioannidis JP (2003). The association of P-glycoprotein with response to chemotherapy and clinical outcome in patients with osteosarcoma. A meta-analysis. Cancer, 98, 581-9.
24. Pakos EE, Kyzas PA, Ioannidis JP (2004). Prognostic significance of TP53 tumor suppressor gene expression and mutations in human osteosarcoma: a meta-analysis. Clin Cancer Res, 10, 6208-14.
25. Petitti DB (2000). Meta-analysis, decision analysis, and costeffectiveness analysis: methods for quantitative synthesis in medicine. New York, Oxford University Press.
26. Qu JT, Wang M, He HL, Tang Y, Ye XJ (2012). The prognostic value of elevated vascular endothelial growth factor in patients with osteosarcoma: a meta-analysis and systemic review. J Cancer Res Clin Oncol, 138, 819-25.
27. Salas S, Bartoli C, Deville JL, et al (2007). Ezrin and alpha-smooth muscle actin are immunohistochemical prognostic markers in conventional osteosarcomas. Virchows Arch, 451, 999-1007.
28. Shi RL, Li JF, Qu Y, et al (2006). Expression of Ezrin in gastric carcinoma and its significance. Zhonghua Wei Chang Wai Ke Za Zhi, 9, 433-5.
29. Stang A (2010). Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol, 25, 603-5.
30. Sun CX, Robb VA, Gutmann DH (2002). Protein 4.1 tumor suppressors: getting a FERM grip on growth regulation. J Cell Sci, 115, 3991-4000.
31. Vaheri A, Carpen O, Heiska L, et al (1997). The ezrin protein family: membrane-cytoskeleton interactions and disease associations. Curr Opin Cell Biol, 9, 659-66.
32. Wang HJ, Zhu JS, Zhang Q, Sun Q, Guo H (2009). High level of ezrin expression in colorectal cancer tissues is closely related to tumor malignancy. World J Gastroenterol, 15, 2016-9.
33. Wang YF, Shen JN, Xie XB, Wang J, Huang G (2011). Expression change of ezrin as a prognostic factor in primary osteosarcoma. Med Oncol, 28, S636-43.
34. Xu-dong S, Feng LIN, Ping C, et al (2008). Expression of Ezrin protein and its relationship with lung metastasis and survival time of osteosarcoma patients. TUMOR, 28, 4.
35. Xu-Dong S, Zan S, Shui-er Z, et al (2009). Expression of Ezrin correlates with lung metastasis in Chinese patients with osteosarcoma. Clin Invest Med, 32, E180-8.
36. You-yuan W, Wei-liang C, Zhao-hui Y, et al (2009). Effects of Ezrin gene on the proliferation and invasion activity of human salivary gland adenoid cystic carcinoma. Chin J Stomatol, 44, 5.
37. Yu Y, Khan J, Khanna C, et al (2004). Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat Med, 10, 175-81.