Surveillance study of species distribution, antifungal susceptibility and mortality of nosocomial candidemia in a tertiary care hospital in China

BMC Infectious Diseases

Volumn 13, Issue 1, 2013, Pages

  Ma, Chun fang ^a   Li, Fang qiu ^a,b   Shi, Li ning ^a   Hu, Yu an ^a   Wang, Ying ^a   Huang, Mei ^a   Kong, Qian qian ^a  

^a NANJING UNIVERSITY   (China)

^b JINLING HOSPITAL   (China)

Author keywords

Antifungal susceptibility; Mortality; Nosocomial candidemia; Risk factors

Indexed keywords

FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; VORICONAZOLE;

ABDOMINAL SURGERY; ADOLESCENT; ADULT; AGED; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; CANDIDA ALBICANS; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CANDIDEMIA; CENTRAL VENOUS CATHETER; CHILD; CHINA; CLINICAL FEATURE; DEMOGRAPHY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SURVEILLANCE; ELECTRONIC MEDICAL RECORD; FEMALE; HOSPITAL DISCHARGE; HOSPITAL INFECTION; HUMAN; INCIDENCE; INFANT; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; NEUTROPENIA; PRESCHOOL CHILD; RISK FACTOR; SCHOOL CHILD; SPECIES DISTRIBUTION; SURVIVAL; TERTIARY HEALTH CARE; TREATMENT RESPONSE; TREND STUDY;

EID: 84880335852     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-13-337     Document Type: Article

References (46)

1. Tortorano AM, Dho G, Prigitano A, Breda G, Grancini A, Emmi V, Cavanna C, Marino G, Morero S, Ossi C. Invasive fungal infections in the intensive care unit: a multicentre, prospective, observational study in Italy (2006-2008). Mycoses 2012, 55(1):73-79. 10.1111/j.1439-0507.2011.02044.x, 21668521.
2. Kourkoumpetis T, Manolakaki D, Velmahos G, Chang Y, Alam HB, De Moya MM, Sailhamer EA, Mylonakis E. Candida infection and colonization among non-trauma emergency surgery patients. Virulence 2010, 1(5):359. 10.4161/viru.1.5.12795, 21178471.
3. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 2004, 39(3):309-317. 10.1086/421946, 15306996.
4. Marchetti O, Bille J, Fluckiger U, Eggimann P, Ruef C, Garbino J, Calandra T, Glauser MP, Täuber MG, Pittet D. Epidemiology of candidemia in Swiss tertiary care hospitals: secular trends, 1991-2000. Clin Infect Dis 2004, 38(3):311-320. 10.1086/380637, 14727199.
5. Poikonen E, Lyytikäinen O, Anttila VJ, Koivula I, Lumio J, Kotilainen P, Syrjälä H, Ruutu P. Secular trend in candidemia and the use of fluconazole in Finland, 2004-2007. BMC Infect Dis 2010, 10(1):312. 10.1186/1471-2334-10-312, 2988049, 21029444.
6. Zaragoza R, Pemán J. The diagnostic and therapeutic approach to fungal infections in critical care settings. Adv Sepsis 2008, 6:90-98.
7. Tortorano A, Peman J, Bernhardt H, Klingspor L, Kibbler C, Faure O, Biraghi E, Canton E, Zimmermann K, Seaton S. Epidemiology of candidaemia in Europe: results of 28-month European Confederation of Medical Mycology (ECMM) hospital-based surveillance study. Eur J Clin Microbiol Infect Dis 2004, 23(4):317-322. 10.1007/s10096-004-1103-y, 15029512.
8. De Rosa FG, Trecarichi EM, Montrucchio C, Losito AR, Raviolo S, Posteraro B, Corcione S, Di Giambenedetto S, Fossati L, Sanguinetti M. Mortality in patients with early-or late-onset candidaemia. J Antimicrob Chemother 2013, 68(4):927-935. 10.1093/jac/dks480, 3594494, 23236102.
9. Olaechea P, Palomar M, León-Gil C, Alvarez-Lerma F, Jorda R, Nolla-Salas J, León-Regidor M. Economic impact of Candida colonization and Candida infection in the critically ill patient. Eur J Clin Microbiol Infect Dis 2004, 23(4):323-330. 10.1007/s10096-004-1104-x, 15024623.
10. Oberoi JK, Wattal C, Goel N, Raveendran R, Datta S, Prasad K. Non-albicans Candida species in blood stream infections in a tertiary care hospital at New Delhi, India. Indian J Med Res 2012, 136(6):997. 3612330, 23391796.
11. Magill SS, Shields C, Sears CL, Choti M, Merz WG. Triazole cross-resistance among Candida spp.: case report, occurrence among bloodstream isolates, and implications for antifungal therapy. J Clin Microbiol 2006, 44(2):529-535. 10.1128/JCM.44.2.529-535.2006, 1392670, 16455909.
12. Leroy O, Gangneux JP, Montravers P, Mira JP, Gouin F, Sollet JP, Carlet J, Reynes J, Rosenheim M, Regnier B. Epidemiology, management, and risk factors for death of invasive Candida infections in critical care: a multicenter, prospective, observational study in France (2005-2006). Crit Care Med 2009, 37(5):1612-1618. 10.1097/CCM.0b013e31819efac0, 19325476.
13. Asmundsdottir LR, Erlendsdottir H, Gottfredsson M. Nationwide Study of Candidemia, Antifungal Use, and Antifungal Drug Resistance in Iceland, 2000 to 2011. J Clin Microbiol 2013, 51(3):841-848. 10.1128/JCM.02566-12, 23269738.
14. Li FQ, Ma CF, Shi LN, Lu JF, Wang Y, Huang M, Kong QQ. Diagnostic value of immunoglobulin G antibodies against Candida enolase and fructose-bisphosphate aldolase for candidemia. BMC Infect Dis 2013, 13:253. 10.1186/1471-2334-13-253, 3673856, 23725337.
15. Almirante B, Rodríguez D, Park BJ, Cuenca-Estrella M, Planes AM, Almela M, Mensa J, Sanchez F, Ayats J, Gimenez M. Epidemiology and predictors of mortality in cases of Candida bloodstream infection: results from population-based surveillance, Barcelona, Spain, from 2002 to 2003. J Clin Microbiol 2005, 43(4):1829-1835. 10.1128/JCM.43.4.1829-1835.2005, 1081396, 15815004.
16. Colosi I, Faure O, Lebeau B, Colosi H, Junie M, Pelloux H. Comparison of two methods, E-test® and Neo-Sensitabs® tablet diffusion assay, for testing susceptibility of 93 Candida strains to amphotericin B, fluconazole, voriconazole, and caspofungin. Rev Sci Parasitol 2009, 10(1/2):112-122.
17. Diekema DJ, Messer SA, Hollis RJ, Boyken L, Tendolkar S, Kroeger J, Jones RN, Pfaller MA. A global evaluation of voriconazole activity tested against recent clinical isolates of < i > Candida spp. Diagn Microbiol Infect Dis 2009, 63(2):233-236. 10.1016/j.diagmicrobio.2008.11.001, 19070452.
18. Marcos-Arias C, Eraso E, Madariaga L, Carrillo-Muñoz AJ, Quindós G. In Vitro Activities of New Triazole Antifungal Agents, Posaconazole and Voriconazole, Against Oral Candida Isolates from Patients Suffering from Denture Stomatitis. Mycopathologia 2012, 173(1):35-46. 10.1007/s11046-011-9460-4, 21842426.
19. Arendrup MC, Bruun B, Christensen JJ, Fuursted K, Johansen HK, Kjældgaard P, Knudsen JD, Kristensen L, Møller J, Nielsen L. National surveillance of fungemia in Denmark (2004 to 2009). J Clin Microbiol 2011, 49(1):325-334. 10.1128/JCM.01811-10, 3020479, 20980569.
20. Rennert G, Rennert H, Pitlik S, Finkelstein R, Kitzes-Cohen R. Epidemiology of candidemia-a nationwide survey in Israel. Infection 2000, 28(1):26-29. 10.1007/s150100050006, 10697787.
21. Li D, Zhang W, Zheng S, Ma Z, Zhang P, Liu Z. Surveillance study of candidemia in cancer patients in North China. Med Mycol 2013, 51(4):378-384. 10.3109/13693786.2012.727481, 23046201.
22. Motta AL, Almeida GMD, Almeida Júnior JN, Burattini MN, Rossi F. Candidemia epidemiology and susceptibility profile in the largest Brazilian teaching hospital complex. Braz J Infect Dis 2010, 14(5):441-448.
23. Roilides E. Invasive candidiasis in neonates and children. Early Hum Dev 2011, 87:S75-S76.
24. Fridkin SK. Candidemia is costly-plain and simple. Clin Infect Dis 2005, 41(9):1240-1241. 10.1086/496935, 16206096.
25. Hajjeh RA, Sofair AN, Harrison LH, Lyon GM, Arthington-Skaggs BA, Mirza SA, Phelan M, Morgan J, Lee-Yang W, Ciblak MA. Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program. J Clin Microbiol 2004, 42(4):1519-1527. 10.1128/JCM.42.4.1519-1527.2004, 387610, 15070998.
26. Pfaller M, Diekema D. Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 2007, 20(1):133-163. 10.1128/CMR.00029-06, 1797637, 17223626.
27. Fridkin SK, Kaufman D, Edwards JR, Shetty S, Horan T. Changing incidence of Candida bloodstream infections among NICU patients in the United States: 1995-2004. Pediatrics 2006, 117(5):1680-1687. 10.1542/peds.2005-1996, 16651324.
28. Chang A, Neofytos D, Horn D. Candidemia in the 21st century. Future Microbiol 2008, 3(4):463-472. 10.2217/17460913.3.4.463, 18651817.
29. Shetty SS, Harrison LH, Hajjeh RA, Taylor T, Mirza SA, Schmidt AB, Sanza LT, Shutt KA, Fridkin SK. Determining risk factors for candidemia among newborn infants from population-based surveillance: Baltimore, Maryland, 1998-2000. Pediatr Infect Dis J 2005, 24(7):601-604. 10.1097/01.inf.0000168751.11375.d6, 15999000.
30. Lerolle N, Trinquart L, Bornstain C, Tadié JM, Imbert A, Diehl JL, Fagon JY, Guérot E. Increased intensity of treatment and decreased mortality in elderly patients in an intensive care unit over a decade. Crit Care Med 2010, 38(1):59. 10.1097/CCM.0b013e3181b088ec, 19633539.
31. Halpern NA, Pastores SM. Critical care medicine in the United States 2000-2005: An analysis of bed numbers, occupancy rates, payer mix, and costs. Crit Care Med 2010, 38(1):65. 10.1097/CCM.0b013e3181b090d0, 19730257.
32. Giri S, Kindo AJ. A review of Candida species causing blood stream infection. Indian J Med Microbiol 2012, 30(3):270-278. 10.4103/0255-0857.99484, 22885191.
33. Ann Chai LY, Denning DW, Warn P. Candida tropicalis in human disease. Crit Rev Microbiol 2010, 36(4):282-298. 10.3109/1040841X.2010.489506, 20883082.
34. Wu J-Q, Zhu L-P, Ou X-T, Xu B, Hu X-P, Wang X, Weng X-H. Epidemiology and risk factors for non-Candida albicans candidemia in non-neutropenic patients at a Chinese teaching hospital. Medical Mycology 2011, 49(5):552-555.
35. Pfaller M, Diekema D, Gibbs D, Newell V, Bijie H, Dzierzanowska D, Klimko N, Letscher-Bru V, Lisalova M, Muehlethaler K. Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: 10.5-year analysis of susceptibilities of noncandidal yeast species to fluconazole and voriconazole determined by CLSI standardized disk diffusion testing. J Clin Microbiol 2009, 47(1):117-123. 10.1128/JCM.01747-08, 2620874, 19005141.
36. Peman J, Canton E, Gobernado M. Epidemiology and antifungal susceptibility of Candida species isolated from blood: results of a 2-year multicentre study in Spain. Eur J Clin Microbiol Infect Dis 2005, 24(1):23-30. 10.1007/s10096-004-1267-5, 15619060.
37. Ostrosky-Zeichner L, Lashof AO, Kullberg B, Rex J. Voriconazole salvage treatment of invasive candidiasis. Eur J Clin Microbiol Infect Dis 2003, 22(11):651-655. 10.1007/s10096-003-1014-3, 14564539.
38. Muñoz P, Sánchez-Somolinos M, Alcalá L, Rodríguez-Créixems M, Peláez T, Bouza E. Candida krusei fungaemia: antifungal susceptibility and clinical presentation of an uncommon entity during 15 years in a single general hospital. J Antimicrob Chemother 2005, 55(2):188-193. 10.1093/jac/dkh532, 15650001.
39. Diekema D, Messer S, Brueggemann A, Coffman S, Doern G, Herwaldt L, Pfaller M. Epidemiology of candidemia: 3-year results from the emerging infections and the epidemiology of Iowa organisms study. J Clin Microbiol 2002, 40(4):1298-1302. 10.1128/JCM.40.4.1298-1302.2002, 140380, 11923348.
40. Xess I, Jain N, Hasan F, Mandal P, Banerjee U. Epidemiology of candidemia in a tertiary care centre of north India: 5-year study. Infection 2007, 35(4):256-259. 10.1007/s15010-007-6144-6, 17646917.
41. Quindós G, Abarca L, Carrillo-Muñoz AJ, Arévalo MP, Bornay FJ, Casals JB, Molina JMH, Iglesias I, Linares M, Martín-Mazuelos E. Multicenter survey of in vitro antifungal resistance in yeasts of medical importance isolated from Spanish patients. Rev Iberoam Micol 1999, 16:97-100.
42. Bassetti M, Righi E, Costa A, Fasce R, Molinari MP, Rosso R, Pallavicini FB, Viscoli C. Epidemiological trends in nosocomial candidemia in intensive care. BMC Infect Dis 2006, 6(1):21. 10.1186/1471-2334-6-21, 1379648, 16472387.
43. Bassetti M, Trecarichi EM, Righi E, Sanguinetti M, Bisio F, Posteraro B, Soro O, Cauda R, Viscoli C, Tumbarello M. Incidence, risk factors, and predictors of outcome of candidemia. Survey in 2 Italian university hospitals. Diagn Microbiol Infect Dis 2007, 58(3):325-331. 10.1016/j.diagmicrobio.2007.01.005, 17350205.
44. Al-Tawfiq JA. Distribution and epidemiology of Candida species causing fungemia at a Saudi Arabian hospital. Int J Infect Dis 2007, 11:239-244. 10.1016/j.ijid.2006.03.003, 16859945.
45. Costa S, Marinho I, Araujo E, Manrique A, Levin E. Nosocomial fungaemia: a 2-year prospective study. J Hosp Infect 2000, 45(1):69-72. 10.1053/jhin.1999.0670, 10917780.
46. Blumberg HM, Jarvis WR, Soucie JM, Edwards JE, Patterson JE, Pfaller MA, Rangel-Frausto MS, Rinaldi MG, Saiman L, Wiblin RT. Risk factors for candidal bloodstream infections in surgical intensive care unit patients: the NEMIS prospective multicenter study. Clin Infect Dis 2001, 33(2):177-186. 10.1086/321811, 11418877.