Loss in connectivity among regions of the brain reward system in alcohol dependence

Human Brain Mapping

Volumn 34, Issue 12, 2013, Pages 3129-3142

  Kuceyeski, Amy ^a   Meyerhoff, Dieter J ^b,c   Durazzo, Timothy C ^b,c   Raj, Ashish ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Addiction; Alcohol dependence; Brain reward system; Structural brain connectivity; Tractography; White matter injury

Indexed keywords

ALCOHOL;

ADULT; ALCOHOL CONSUMPTION; ALCOHOL USE DISORDER; ALCOHOLISM; ARTICLE; BRAIN FUNCTION; BRAIN REGION; BRAIN REWARD SYSTEM; CEREBELLUM; CONTROLLED STUDY; DIENCEPHALON; DRINKING; FEMALE; GRAY MATTER; HUMAN; IMAGE PROCESSING; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REWARD; SMOKING; TRACTOGRAPHY; WHITE MATTER; WHITE MATTER INJURY;

ADDICTION; ALCOHOL DEPENDENCE; BRAIN REWARD SYSTEM; STRUCTURAL BRAIN CONNECTIVITY; TRACTOGRAPHY; WHITE MATTER INJURY;

ADULT; AGE FACTORS; ALCOHOLISM; ATROPHY; BRAIN; BRAIN MAPPING; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; LEUKOENCEPHALOPATHIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURAL PATHWAYS; REWARD; YOUNG ADULT;

EID: 84880332845     PISSN: 10659471     EISSN: 10970193     Source Type: Journal    
DOI: 10.1002/hbm.22132     Document Type: Article

References (61)

1. Ad-Dab'bagh Y, Einarson D, Lyttelton O, Muehlboeck JS, Mok K, Ivanov O, Vincent RD, Lepage C, Lerch J, Fombonne E, Evans AC (2006): The CIVET image-processing environment: A fully automated comprehensive pipeline for anatomical neuorimaging research. Proceedings of the 12th Annual Meeting of the Organization for Human Brain Mapping (OHBM), p2266.
2. Alemán-Gómez Y, Melie-García L, Valdés-Hernandez P (2005): IBASPM: Toolbox for automatic parcellation of brain structures. Presented at the 12th Annual Meeting of the Organization for Human Brain Mapping, Florence, Italy.
3. Alfonso-Loeches S, Guerri C (2011): Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain. Crit Rev Clin Lab Sci 48:19-47.
4. Aralasmak A, Ulmer JL, Kocak M, Salvan CV, Hillis AE, Yousem DM (2006): Association, commissural, and projection pathways and their functional deficit reported in literature. J Comput Assist Tomogr 30:695-715.
5. Bartzokis G (2004): Quadratic trajectories of brain myelin content: Unifying construct for neuropsychiatric disorders. Neurobiol Aging 25:49-62.
6. Bendlin BB, Ries ML, Canu E, Sodhi A, Lazar M, Alexander A, Carlsson C, Sager M, Asthana S, Johnson SC (2010): White matter is altered with parental family history of Alzheimer's disease. Alzheimers Dement 6:9.
7. Cardenas VA, Studholme C, Gazdzinski S, Durazzo TC, Meyerhoff DJ (2007): Deformation-based morphometry of brain changes in alcohol dependence and abstinence. NeuroImage 34:879-887.
8. Cardenas VA, Durazzo TC, Gazdzinski S, Mon A, Studholme C, Meyerhoff DJ (2011): Brain morphology at entry into treatment for alcohol dependence is related to relapse propensity. Biol Psychiatry 70:561-567.
9. Crews FT, Nixon K (2009): Mechanisms of neurodegeneration and regeneration in alcoholism. Alcohol 44:115-127.
10. Durazzo TC, Gazdzinski S, Banys P, Meyerhoff DJ (2004): Cigarette smoking exacerbates chronic alcohol-induced brain damage: A preliminary metabolite imaging study. Alcohol Clin Exp Res 28:1849-1860.
11. Durazzo TC, Meyerhoff DJ (2007): Neurobiological and neurocognitive effects of chronic cigarette smoking and alcoholism. Front Biosci 12:4079-4100.
12. Durazzo TC, Pathak V, Gazdzinski S, Mon A, Meyerhoff DJ (2010): Metabolite levels in the brain reward pathway discriminate those who remain abstinent from those who resume hazardous alcohol consumption after treatment for alcohol dependence. J Stud Alcohol Drug 71:278-289.
13. Durazzo TC, Tosun D, Buckley S, Gazdzinski S, Mon A, Fryer SL, Meyerhoff DJ (2011): Cortical thickness, surface area, and volume of the brain reward system in alcohol dependence: Relationships to relapse and extended abstinence. Alcohol Clin Exp Res 35:1187-1200.
14. Durazzo TC, Mon A, Gazdzinski S, Meyerhoff DJ (2011): Chronic cigarette smoking in alcohol dependence: Associations with cortical thickness and N-acetylaspartate levels in the extended brain reward system. Addict Biol. doi:10.1111/j.1369-1600.2011.00407.x.
15. Filley CM (2005): White matter and behavioral neurology. Ann N Y Acad Sci 1064:162-183.
16. Fineberg NA, Potenza MN, Chamberlain SR, Berlin HA, Menzies L, Bechara A, Sahakian BJ, Robbins TW, Bullmore ET, Hollander E (2010): Probing compulsive and impulsive behaviors, from animal models to endophenotypes: A narrative review. Neuropsychopharmacology 35:591-604.
17. First M, Spitzer R, Gibbon M, Williams J (1998):Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0:8/98 revision).New York:Biometrics Research Department.
18. Friston K, Ashburner J, Kiebel S, Nichols T, Penny W.2007.Statistical Parametric Mapping: The Analysis of Functional Brain Images.Elsevier.
19. Gazdzinski S, Durazzo TC, Studholme C, Song E, Banys P, Meyerhoff DJ (2005): Quantitative brain MRI in alcohol dependence: Preliminary evidence for effects of concurrent chronic cigarette smoking on regional brain volumes. Alcohol Clin Exp Res 29:1484-1495.
20. Gazdzinski S, Durazzo TC, Mon A, Yeh P-H, Meyerhoff DJ (2010): Cerebral white matter recovery in abstinent alcoholics-A multimodality magnetic resonance study. Brain 133:1043-1053.
21. Gazdzinski S, Durazzo TC, Yeh P-H, Hardin D, Banys P, Meyerhoff DJ (2008): Chronic cigarette smoking modulates injury and short-term recovery of the medial temporal lobe in alcoholics. Psychiatry Res 162:133-145.
22. Genovese C, Wasserman L (2002): Operating characteristics and extensions of the false discovery rate procedure. J R Stat Soc Ser B 64:499-517.
23. George O, Koob GF (2010): Individual differences in prefrontal cortex function and the transition from drug use to drug dependence. Neurosci Biobehav Rev 35:232-247.
24. Gold BT, Powell DK, Andersen AH, Smith CD (2010): Alterations in multiple measures of white matter integrity in normal women at high risk for Alzheimer's disease. NeuroImage 52:1487-1494.
25. Griswold MA, Jakob PM, Heidemann RM, Nittka M, Jellus V, Wang J, Kiefer B, Haase A (2002): Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med 47:1202-1210.
26. Harper C, Matsumoto I, Pfefferbaum A, Adalsteinsson E, Sullivan EV, Lewohl J, Dodd P, Taylor M, Fein G, Landman B (2005): The pathophysiology of brain shrinkage in alcoholics structural and molecular changes and clinical implications. Alcohol: Clin Exp Res 29:1106-1115.
27. Heinz A, Beck A, Grüsser SM, Grace AA, Wrase J (2009): Identifying the neural circuitry of alcohol craving and relapse vulnerability. Addict Biol 14:108-118.
28. Kochunov P, Thompson PM, Lancaster JL, Bartzokis G, Smith S, Coyle T, Royall DR, Laird A, Fox PT (2007): Relationship between white matter fractional anisotropy and other indices of cerebral health in normal aging: Tract-based spatial statistics study of aging. Neuroimage 35:478-487.
29. Kolb B, Whishaw I.2009.Fundamentals of Human Neuropsychology.Worth Publishers.
30. Koob GF, Volkow ND (2010): Neurocircuitry of addiction. Neuropsychopharmacology 35:217-238.
31. Krzanowski WJ.1988.Principles of Multivariate Analysis: A User's Perspective. Clarendon Press.
32. Kuceyeski A, Maruta J, Niogi SN, Ghajar J, Raj A (2011): The generation and validation of white matter connectivity importance maps. NeuroImage 58:109-121.
33. Kuceyeski A, Raj A (2011): Investigating correlations of cortical atrophy and white matter integrity loss in Alzheimer's subjects using connectivity information. Alzheimer's Association International Conference on Alzheimer's Disease, Paris, France, p16242.
34. Kuceyeski A, Zhang Y, Raj A (2012): Linking white matter connectivity integrity loss to associated cortical regions using structural connectivity information in Alzheimer's disease and fronto-temporal dementia: The Loss in Connectivity (LoCo) score. NeuroImage 61:1311-1323.
35. Lo C-Y, Wang P-N, Chou K-H, Wang J, He Y, Lin C-P (2010): Diffusion tensor tractography reveals abnormal topological organization in structural cortical networks in Alzheimer's disease. J Neurosci 30:16876-16885.
36. Makris N, Gasic GP, Kennedy DN, Hodge SM, Kaiser JR, Lee MJ, Kim BW, Blood AJ, Evins AE, Seidman LJ, Iosifescu DV, Lee S, Baxter C, Perlis RH, Smoller JW, Fava M, Breiter HC (2008a): Cortical thickness abnormalities in cocaine addiction-A reflection of both drug use and a pre-existing disposition to drug abuse?Neuron 60:174-188.
37. Makris N, Oscar-Berman M, Jaffin SK, Hodge SM, Kennedy DN, Caviness VS, Marinkovic K, Breiter HC, Gasic GP, Harris GJ (2008b): Decreased volume of the brain reward system in alcoholism. Biol Psychiatry 64:192-202.
38. Meyerhoff DJ, Durazzo TC, Ende G (2011): Chronic alcohol consumption, abstinence and relapse: Brain proton magnetic resonance spectroscopy studies in animals and humans. Curr Top Behav Neurosci.
39. Meyerhoff DJ, Durazzo TC (2008): Proton magnetic resonance spectroscopy in alcohol use disorders: A potential new endophenotype?Alcohol Clin Exp Res 32:1146-1158.
40. Pfefferbaum A, Adalsteinsson E, Sullivan EV (2006): Dysmorphology and microstructural degradation of the corpus callosum: Interaction of age and alcoholism. Neurobiol Aging 27:994-1009.
41. Pfefferbaum A, Rosenbloom MJ, Adalsteinsson E, Sullivan EV (2007): Diffusion tensor imaging with quantitative fibre tracking in HIV infection and alcoholism comorbidity: Synergistic white matter damage. Brain 130:48-64.
42. Pfefferbaum A, Sullivan EV (2005): Disruption of brain white matter microstructure by excessive intracellular and extracellular fluid in alcoholism: Evidence from diffusion tensor imaging. Neuropsychopharmacology 30:423-432.
43. Raj A, Mueller SG, Young K, Laxer KD, Weiner M (2010): Network-level analysis of cortical thickness of the epileptic brain. NeuroImage 52:1302-1313.
44. Rando K, Hong K-I, Bhagwagar Z, Li C-SR, Bergquist K, Guarnaccia J, Sinha R (2011): Association of frontal and posterior cortical gray matter volume with time to alcohol relapse: A prospective study. Am J Psychiatry 168:183-192.
45. Schmahmann JD, Pandya DN, Wang R, Dai G, D'Arceuil HE, Crespigny AJ de, Wedeen VJ (2007): Association fibre pathways of the brain: Parallel observations from diffusion spectrum imaging and autoradiography. Brain 130:630-653.
46. Skinner HA, Sheu WJ (1982): Reliability of alcohol use indices. The lifetime drinking history and the MAST. J Stud Alcohol 43:1157-1170.
47. Smith CD, Chebrolu H, Andersen AH, Powell DA, Lovell MA, Xiong S, Gold BT (2010): White matter diffusion alterations in normal women at risk of Alzheimer's disease. Neurobiol Aging 31:1122-1131.
48. Smith SM andNichols TE (2009): Threshold-free cluster enhancement: Addressing problems of smoothing, threshold dependence and localisation in cluster inference. NeuroImage 44:83-98.
49. Sobell LC, Sobell MB, Riley DM, Schuller R, Pavan DS, Cancilla A, Klajner F, Leo GI (1988): The reliability of alcohol abusers' self-reports of drinking and life events that occurred in the distant past. J Stud Alcohol 49:225-232.
50. Sobell LC, Sobell MB (1990): Self-report issues in alcohol abuse: State of the art and future directions. Behav Assess 12:91-106.
51. Sullivan EV (2007): Alcohol and drug dependence: Brain mechanisms and behavioral impact. Neuropsychol Rev 17:235-238.
52. Sullivan EV, Rohlfing T, Pfefferbaum A (2010): Quantitative fiber tracking of lateral and interhemispheric white matter systems in normal aging: Relations to timed performance. Neurobiol Aging 31:464-481.
53. Sullivan EV, Pfefferbaum A (2005): Neurocircuitry in alcoholism: A substrate of disruption and repair. Psychopharmacology 180:583-594.
54. Tessner KD, Hill SY (2010): Neural circuitry associated with risk for alcohol use disorders. Neuropsychol Rev 20:1-20.
55. Volkow ND, Wang G-J, Fowler JS, Tomasi D, Telang F, Baler R (2010): Addiction: Decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain's control circuit. Bioessays 32:748-755.
56. Volkow ND, Wang G-J, Fowler JS, Tomasi D, Telang F (2011): Quantification of behavior sackler colloquium: Addiction: Beyond dopamine reward circuitry. Proc Natl Acad Sci USA 108:15037-15042.
57. Wang X, E.K. Michaelis (2010): Selective neuronal vulnerability to oxidative stress in the brain. Front Aging Neurosci 2:12.
58. Wen W, Zhu W, He Y, Kochan NA, Reppermund S, Slavin MJ, Brodaty H, Crawford J, Xia A, Sachdev P (2011): Discrete neuroanatomical networks are associated with specific cognitive abilities in old age. J Neurosci 31:1204-1212.
59. Yeh P-H, Simpson K, Durazzo TC, Gazdzinski S, Meyerhoff DJ (2009): Tract-based spatial statistics (TBSS) of diffusion tensor imaging data in alcohol dependence: Abnormalities of the motivational neurocircuitry. Psychiatry Res 173:22-30.
60. Zalesky A, Fornito A, Bullmore ET (2010): Network-based statistic: Identifying differences in brain networks. NeuroImage 53:1197-1207.
61. Zhang X, Salmeron BJ, Ross TJ, Geng X, Yang Y, Stein EA (2011): Factors underlying prefrontal and insula structural alterations in smokers. NeuroImage 54:42-48.