Mutation of the NPM1 gene contributes to the development of donor cell-derived acute myeloid leukemia after unrelated cord blood transplantation for acute lymphoblastic leukemia

Human Pathology

Volumn 44, Issue 8, 2013, Pages 1696-1699

  Rodríguez Macías, Gabriela ^a   Martínez Laperche, Carolina ^a,b   Gayoso, Jorge ^a,b   Noriega, Víctor ^c   Serrano, David ^a,b   Balsalobre, Pascual ^a,b   Muñoz Martínez, Cristina ^a   Díez Martín, José L ^a,b   Buño, Ismael ^a,b  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Acute myeloid leukemia; Chimerism; Cord blood transplantation; Donor cell leukemia; NPM1 gene mutation

Indexed keywords

BUSULFAN; CD11B ANTIGEN; CD14 ANTIGEN; CD15 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD56 ANTIGEN; CD64 ANTIGEN; CYCLOSPORIN A; DNA FRAGMENT; FLUDARABINE; GANCICLOVIR; HLA DR ANTIGEN; MICROSOMAL AMINOPEPTIDASE; MYCOPHENOLIC ACID; NUCLEOPHOSMIN; THIOTEPA; THYMOCYTE ANTIBODY;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; ASTHENIA; BASE MISPAIRING; BONE MARROW CELL; BONE MARROW EXAMINATION; CANCER CHEMOTHERAPY; CANCER MORTALITY; CASE REPORT; CAUSE OF DEATH; CHIMERA; CORD BLOOD STEM CELL TRANSPLANTATION; CYTOMEGALOVIRUS INFECTION; DISEASE COURSE; DONOR; DONOR CELL LEUKEMIA; FEMALE; FEVER; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; GRAFT VERSUS HOST REACTION; HEMODIALYSIS; HUMAN; IMMUNOPHENOTYPING; KARYOTYPE 46,XX; KARYOTYPING; KIDNEY FAILURE; LEUKEMIA REMISSION; LEUKEMOGENESIS; LEUKOCYTE COUNT; MEDICAL HISTORY; PLASMA TRANSFUSION; RECURRENT VIRUS INFECTION; TREATMENT DURATION; UMBILICAL CORD BLOOD; UPPER RESPIRATORY TRACT INFECTION;

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOID LEUKEMIA; ALL; AML; CHIMERISM; COMPLETE REMISSION; CORD BLOOD TRANSPLANTATION; CR; DCL; DONOR CELL LEUKEMIA; FISH; FLUORESCENCE IN SITU HYBRIDIZATION; GRAFT-VERSUS-HOST-DISEASE; GVHD; NPM1; NPM1 GENE MUTATION; NUCLEOPHOSMIN; QPCR; REAL-TIME QUANTITATIVE POLYMERASE CHAIN REACTION; SCT; STEM CELL TRANSPLANTATION; UCBT; UNRELATED CORD BLOOD TRANSPLANTATION;

ADULT; CORD BLOOD STEM CELL TRANSPLANTATION; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, MYELOID, ACUTE; MUTATION; NUCLEAR PROTEINS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REAL-TIME POLYMERASE CHAIN REACTION; TRANSPLANTATION, HOMOLOGOUS; UNRELATED DONORS;

EID: 84880331723     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2013.01.001     Document Type: Article

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