Heart rate before ICU discharge: A simple and readily available predictor of short- and long-term mortality from critical illness

Clinical Research in Cardiology

Volumn 102, Issue 8, 2013, Pages 599-606

  Grander, Wilhelm ^a   Müllauer, Kathrin ^a   Koller, Bernhard ^a   Tilg, Herbert ^a   Dünser, Martin ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

C reactive protein; Critical illness; Heart rate; Intensive care unit; Long and short term mortality; Post ICU long term mortality

Indexed keywords

C REACTIVE PROTEIN;

ADULT; AGED; ARTICLE; CRITICAL ILLNESS; DISEASE SEVERITY; FEMALE; FOLLOW UP; HEART RATE; HOSPITAL DISCHARGE; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; INFLAMMATION; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; POST HOC ANALYSIS; PREDICTIVE VALUE; PROTEIN BLOOD LEVEL; SURVIVAL;

AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; CRITICAL ILLNESS; DATABASES, FACTUAL; FOLLOW-UP STUDIES; HEART RATE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATIENT DISCHARGE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 84880329510     PISSN: 18610684     EISSN: 18610692     Source Type: Journal    
DOI: 10.1007/s00392-013-0571-4     Document Type: Article

References (32)

1. Levine HJ (1997) Rest heart rate and life expectancy. J Am Coll Cardiol 30(4):1104-1106
2. Hoke RS, Muller-Werdan U, Lautenschlager C et al (2012) Heart rate as an independent risk factor in patients with multiple organ dysfunction: a prospective, observational study. Clin Res Cardiol 101(2):139-147
3. Tracey KJ (2009) Reflex control of immunity. Nat Rev Immunol 9(6):418-428
4. Bone RC, Balk RA, Cerra FB et al (2009) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. 1992. Chest 136(5 Suppl):e28
5. Kannel WB, Kannel C, Paffenbarger RS Jr et al (1987) Heart rate and cardiovascular mortality: the Framingham Study. Am Heart J 113(6):1489-1494
6. Hansen TW, Thijs L, Boggia J et al (2008) Prognostic value of ambulatory heart rate revisited in 6928 subjects from 6 populations. Hypertension 52(2):229-235
7. Kristal-Boneh E, Silber H, Harari G, Froom P (2000) The association of resting heart rate with cardiovascular, cancer and all-cause mortality: eight year follow-up of 3527 male Israeli employees (the CORDIS Study). Eur Heart J 21:116-124
8. Lechat P, Hulot JS, Escolano S et al (2001) Heart rate and cardiac rhythm relationships with bisoprolol benefit in chronic heart failure in CIBIS II Trial. Circulation 103(10):1428-1433
9. Giannoglou GD, Chatzizisis YS, Zamboulis C et al (2008) Elevated heart rate and atherosclerosis: an overview of the pathogenetic mechanisms. Int J Cardiol 126(3):302-312
10. Palatini P, Julius S (2004) Elevated heart rate: a major risk factor for cardiovascular disease. Clin Exp Hypertens 26:637-644
11. Swedberg K, Komajda M, Bohm M et al (2010) Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study. Lancet 376(9744):875-885
12. Fox K, Ford I, Steg PG et al (2008) Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. Lancet 372(9641):807-816
13. Grander W, Dunser M, Stollenwerk B et al (2010) C-reactive protein levels and post-ICU mortality in nonsurgical intensive care patients. Chest 138(4):856-862
14. Grander W, Luckner G, Orgersen C et al (2011) Peak postoperative C-reactive protein levels and long-term mortality in a mixed surgical ICU population: a retrospective, observational-analytical study. Chirurgia 24(3):125-131
15. Ahmad S, Tejuja A, Newman KD et al (2009) Clinical review: a review and analysis of heart rate variability and the diagnosis and prognosis of infection. Crit Care 13(6):232
16. Kox M, Vrouwenvelder MQ, Pompe JC et al (2011) The effects of brain injury on heart rate variability and the innate immune response in critically ill patients. J Neurotrauma 29(5):747-755
17. Pavlov VA, Tracey KJ (2006) Controlling inflammation: the cholinergic anti-inflammatory pathway. Biochem Soc Trans 34(Pt 6):1037-1040
18. Gallowitsch-Puerta M, Pavlov VA (2007) Neuro-immune interactions via the cholinergic anti-inflammatory pathway. Life Sci 80(24-25):2325-2329
19. Ferrari R, Censi S, Mastrorilli F, Boraso A (2003) Prognostic effects of heart rate reduction in cardiovascular disease. Eur Heart J Suppl 5(Supplement):G10-G14
20. Giannoglou GD, Chatzizisis YS, Zamboulis C et al (2008) Elevated heart rate and atherosclerosis: an overview of the pathogenetic mechanisms. Int J Cardiol 126(3):302-312
21. Heidland UE, Strauer BE (2001) Left ventricular muscle mass and elevated heart rate are associated with coronary plaque disruption. Circulation 104(13):1477-1482
22. Ho KM, Lee KY, Dobb GJ et al (2008) C-reactive protein concentration as a predictor of in-hospital mortality after ICU discharge: a prospective cohort study. Intensive Care Med 34(3):481-487
23. Litton E, Ho KM, Chamberlain J et al (2007) C-reactive protein concentration as a predictor of in-hospital mortality after ICU discharge: a nested case-control study. Crit Care Resusc 9(1):19-25
24. Al-Subaie N, Reynolds T, Myers A et al (2010) C-reactive protein as a predictor of outcome after discharge from the intensive care: a prospective observational study. Br J Anaesth 105(3):318-325
25. Silvestre J, Coelho L, Povoa P (2010) Should C-reactive protein concentration at ICU discharge be used as a prognostic marker? BMC Anesthesiol 10:17
26. Ranzani OT, Prada LF, Zampieri FG, et al (2012) Failure to reduce C-reactive protein levels more than 25% in the last 24 hours before intensive care unit discharge predicts higher in-hospital mortality: a cohort study. J Crit Care 27(5):525.e9-15
27. Ahmadi-Kashani M, Kessler DJ, Day J, Bunch TJ, Stolen KQ, Brown S, Sbaity S, Olshansky B, INTRINSIC RV Study Investigators (2009) Heart rate predicts outcomes in an implantable. Circulation. 120(21):2040-2045
28. Nuding S, Ebelt H, Hoke RS, Krummenerl A, Wienke A, Müller-Werdan U, Werdan K (2011) Reducing elevated heart rate in patients with multiple organ dysfunction syndrome by the I (f) (funny channel current) inhibitor ivabradine: MODI (f)Y trial. Clin Res Cardiol 100(10):915-923
29. Diaz A, Bourassa MG, Guertin MC et al (2005) Long-term prognostic value of resting heart rate in patients with suspected or proven coronary artery disease. Eur Heart J 26(10):967-974
30. Fagundes JE, Castro I (2010) Predictive value of resting heart rate for cardiovascular and all-cause mortality. Arq Bras Cardiol 95(6):713-719
31. Povoa P (2002) C-reactive protein: a valuable marker of sepsis. Intensive Care Med 28(3):235-243
32. Gabay C, Kushner I (1999) Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 340(6):448-454