MR-guided focused ultrasound for acute stroke a rabbit model

Stroke

Volumn 44, Issue SUPPL. 1, 2013, Pages

  Holscher, Thilo ^a   Ahadi, Golnaz ^a   Fisher, David ^a   Zadicario, Eyal ^b   Voie, Arne ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSIGHTEC LTD   (Israel)

Author keywords

Animal models of human disease; Basic science research; Doppler ultrasound; Emergency treatment of stroke; Thrombolysis; Transcranial Doppler

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; CEREBROVASCULAR ACCIDENT; CONFERENCE PAPER; CONTROLLED STUDY; EXPERIMENTAL MODEL; EXPERIMENTAL RABBIT; HIGH INTENSITY FOCUSED ULTRASOUND; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; NEURONAVIGATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; THERMOMETRY; ULTRASOUND SCANNER; ULTRASOUND TRANSDUCER;

ANIMAL MODELS OF HUMAN DISEASE; BASIC SCIENCE RESEARCH; DOPPLER ULTRASOUND; EMERGENCY TREATMENT OF STROKE; THROMBOLYSIS; TRANSCRANIAL DOPPLER;

ANIMALS; CAROTID STENOSIS; HIGH-INTENSITY FOCUSED ULTRASOUND ABLATION; HUMANS; MAGNETIC RESONANCE IMAGING; MICROSCOPY, ELECTRON, SCANNING; RABBITS; SKULL; STROKE; THROMBOLYTIC THERAPY; THROMBOSIS;

EID: 84880319033     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.000688     Document Type: Conference Paper

References (22)

1. Devcic-Kuhar B, Pfaffenberger S, Gherardini L, Mayer C, Gröschl M, Kaun C, et al. Ultrasound affects distribution of plasminogen and tissue-type plasminogen activator in whole blood clots in vitro. Thromb Haemost. 2004;92:980-985.
2. Ishibashi T, Akiyama M, Onoue H, Abe T, Furuhata H. Can transcranial ultrasonication increase recanalization flow with tissue plasminogen activator? Stroke. 2002;33:1399-1404.
3. Daffertshofer M, Huang Z, Fatar M, Popolo M, Schroeck H, Kuschinsky W, et al. Efficacy of sonothrombolysis in a rat model of embolic ischemic stroke. Neurosci Lett. 2004;361:115-119.
4. Datta S, Coussios CC, McAdory LE, Tan J, Porter T, De Courten-Myers G, et al. Correlation of cavitation with ultrasound enhancement of thrombolysis. Ultrasound Med Biol. 2006;32:1257-1267.
5. Holscher T, Raman R, Ernström K, Parrish J, Le DT, Lyden PD, et al. In vitro sonothrombolysis with duplex ultrasound: first results using a simplified model. Cerebrovasc Dis. 2009;28:365-370.
6. Alexandrov AV, Mikulik R, Ribo M, Sharma VK, Lao AY, Tsivgoulis G, et al. A pilot randomized clinical safety study of sonothrombolysis augmentation with ultrasound-activated perflutren-lipid microspheres for acute ischemic stroke. Stroke. 2008;39:1464-1469.
7. Eggers J, König IR, Koch B, Händler G, Seidel G. Sonothrombolysis with transcranial color-coded sonography and recombinant tissue-type plasminogen activator in acute middle cerebral artery main stem occlusion: results from a randomized study. Stroke. 2008;39:1470-1475.
8. Alexandrov AV, Molina CA, Grotta JC, Garami Z, Ford SR, Alvarez-Sabin J, et al; CLOTBUST Investigators. Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N Engl J Med. 2004;351:2170-2178.
9. Molina CA, Barreto AD, Tsivgoulis G, Sierzenski P, Malkoff MD, Rubiera M, et al. Transcranial ultrasound in clinical sonothrombolysis (TUCSON) trial. Ann Neurol. 2009;66:28-38.
10. Molina CA, Ribo M, Rubiera M, Montaner J, Santamarina E, Delgado-Mederos R, et al. Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator. Stroke. 2006;37:425-429.
11. Reed SD, Cramer SC, Blough DK, Meyer K, Jarvik JG. Treatment with tissue plasminogen activator and inpatient mortality rates for patients with ischemic stroke treated in community hospitals. Stroke. 2001;32:1832-1840.
12. Grotta JC, Burgin WS, El-Mitwalli A, Long M, Campbell M, Morgenstern LB, et al. Intravenous tissue-type plasminogen activator therapy for ischemic stroke: Houston experience 1996 to 2000. Arch Neurol. 2001;58:2009-2013.
13. Broussalis E, Trinka E, Hitzl W, Wallner A, Chroust V, Killer-Oberpfalzer M. Comparison of stent-retriever devices versus the Merci retriever for endovascular treatment of acute stroke. AJNR Am J Neuroradiol. 2013;34:366-372.
14. Noorian AR, Gupta R, Nogueira RG. Acute stroke: techniques and results with the Merci retriever. Tech Vasc Interv Radiol. 2012;15:47-52.
15. Dorn F, Stehle S, Lockau H, Zimmer C, Liebig T. Endovascular treatment of acute intracerebral artery occlusions with the solitaire stent: single-centre experience with 108 recanalization procedures. Cerebrovasc Dis. 2012;34:70-77.
16. Soize S, Kadziolka K, Estrade L, Serre I, Bakchine S, Pierot L. Mechanical thrombectomy in acute stroke: prospective pilot trial of the solitaire FR device while under conscious sedation. AJNR Am J Neuroradiol. 2013;34:360-365.
17. Behrens S, Daffertshofer M, Spiegel D, Hennerici M. Low-frequency, low-intensity ultrasound accelerates thrombolysis through the skull. Ultrasound Med Biol. 1999;25:269-273.
18. Frenkel V, Oberoi J, Stone MJ, Park M, Deng C, Wood BJ, et al. Pulsed high-intensity focused ultrasound enhances thrombolysis in an in vitro model. Radiology. 2006;239:86-93.
19. Wright C, Hynynen K, Goertz D. In vitro and in vivo high-intensity focused ultrasound thrombolysis. Invest Radiol. 2012;47:217-225.
20. Rosenschein U, Furman V, Kerner E, Fabian I, Bernheim J, Eshel Y. Ultrasound imaging-guided noninvasive ultrasound thrombolysis: preclinical results. Circulation. 2000;102:238-245.
21. Holscher T, Fisher D, Raman R, Ernstrom K, Zadicario E, Bradley W, et al. Noninvasive transcranial clot lysis using high intensity focused ultrasound. JNN. 2011;S1:1-6.
22. Hölscher T, Fisher DJ, Ahadi G, Voie A. Introduction of a rabbit carotid artery model for sonothrombolysis research. Transl Stroke.Res. 2012;3:397-407.