Transdermal prodrug delivery for radionuclide decorporation: Nonaqueous gel formulation development and in vitro and in vivo assessment

Drug Development Research

Volumn 74, Issue 5, 2013, Pages 322-331

  Zhang, Yong ^a   Sadgrove, Matthew P ^a   Mumper, Russell J ^a   Jay, Michael ^a  

^a University of North Carolina   (United States)

Author keywords

Americium; DTPA; nonaqueous gel; radionuclide decorporation; transdermal drug delivery

Indexed keywords

AMERICIUM 241; C 2E 5; ETHYL CELLULOSE; HYDROCARBON; MIGLYOL; PENTETIC ACID DERIVATIVE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTAMINATED ANIMAL; CONTROLLED STUDY; CREAM; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; FECES; FEMALE; GAMMA COUNTER; GEL; GLASS TRANSITION TEMPERATURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMIDITY; HYDROLYSIS; HYPOTHESIS; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR WEIGHT; NONHUMAN; OINTMENT; PHASE SEPARATION; RAT; SCANNING ELECTRON MICROSCOPY; SINGLE DRUG DOSE; SOLUBILIZATION; THERMAL ANALYSIS; TRANSDERMAL DRUG ADMINISTRATION; URINE; VISCOMETRY; WOUND INFECTION;

EID: 84880308954     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.21082     Document Type: Article

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