Electroconvulsive therapy improves clinical manifestation with plasma BDNF levels unchanged in treatment-resistant depression patients

Neuropsychobiology

Volumn 68, Issue 2, 2013, Pages 110-115

  Lin, Ching Hua ^a   Chen, Ming Chao ^a   Lee, Wen Kuei ^b   Chen, Cheng Chung ^a   Huang, Chiung Hsien ^c   Lane, Hsien Yuan ^c  

^a FOOYIN UNIVERSITY   (Taiwan)

^b Beitoui Armed Forces Psychiatric Hospital   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Brain derived neurotrophic factor; Electroconvulsive therapy; Treatment resistant depression

Indexed keywords

AMFEBUTAMONE; BRAIN DERIVED NEUROTROPHIC FACTOR; FLUOXETINE; MIRTAZAPINE;

ADULT; ARTICLE; CLINICAL GLOBAL IMPRESSION SCALE; DISEASE ASSOCIATION; DISEASE SEVERITY; ELECTROCONVULSIVE THERAPY; FEMALE; GENERAL CONDITION IMPROVEMENT; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL PATIENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PSYCHOPHARMACOTHERAPY; TREATMENT OUTCOME; TREATMENT RESISTANT DEPRESSION; BIPOLAR DEPRESSION; DEPRESSIVE PSYCHOSIS; ELECTROCONVULSIVE THERAPY UNIT; HAMILTON DEPRESSION RATING SCALE; MAJOR DEPRESSION; MIDDLE AGED; REMISSION; SEX DIFFERENCE; TREATMENT RESPONSE;

ADOLESCENT; ADULT; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSIVE DISORDER, TREATMENT-RESISTANT; ELECTROCONVULSIVE THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; TREATMENT OUTCOME;

EID: 84880263739     PISSN: 0302282X     EISSN: 14230224     Source Type: Journal    
DOI: 10.1159/000352013     Document Type: Article

References (48)

1. Fekadu A, Wooderson SC, Markopoulo K, Donaldson C, Papadopoulos A, Cleare AJ: What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies. J Affect Disord 2009; 116:4-11.
2. Sackeim HA: The definition and meaning of treatment-resistant depression. J Clin Psychiatry 2001; 62(suppl 16):10-17.
3. Fava GA, Ruini C, Sonino N: Treatment of recurrent depression: a sequential psycho-therapeutic and psychopharmacological approach. CNS Drugs 2003; 17:1109-1117.
4. Hussain F, Cochrane R: Depression in South Asian women living in the UK: a review of the literature with implications for service provision. Transcult Psychiatry 2004; 41:253-270.
5. Laske C, Eschweiler GW: Brain-derived neu-rotrophic factor: from nerve growth factor to modulator of brain plasticity in cognitive processes and psychiatric diseases (in German). Nervenarzt 2006; 77:523-537.
6. Yamamoto H, Gurney ME: Human platelets contain brain-derived neurotrophic factor. J Neurosci 1990; 10:3469-3478.
7. Aydemir O, Deveci A, Taneli F: The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study. Prog Neuropsychopharmacol Biol Psychiatry 2005; 29: 261-265.
8. Fernandes BS, Gama CS, Cereser KM, Yatham LN, Fries GR, Colpo G, de Lucena D, Kunz M, Gomes FA, Kapczinski F: Brain-derived neu-rotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis. J Psychiatr Res 2011; 45:995-1004.
9. Huang TL, Lee CT, Liu YL: Serum brain-derived neurotrophic factor levels in patients with major depression: effects of antidepres-sa nts. J Psychiatr Res 2008; 42: 521-525.
10. Karege F, Perret G, Bondolfi G, Schwald M, Bertschy G, Aubry JM: Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res 2002; 109:143-148.
11. Shimizu E, Hashimoto K, Okamura N, Koike K, Komatsu N, Kumakiri C, Nakazato M, Watanabe H, Shinoda N, Okada S, Iyo M: Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry 2003; 54: 70-75.
12. Lin PY: State-dependent decrease in levels of brain-derived neurotrophic factor in bipolar disorder: a meta-analytic study. Neurosci Lett 2009; 466:139-143.
13. Molendijk ML, Bus BA, Spinhoven P, Pen-ninx BW, Kenis G, Prickaerts J, Voshaar RC, Elzinga BM: Serum levels of brain-derived neurotrophic factor in major depressive disorder: state-trait issues, clinical features and pharmacological treatment. Mol Psychiatry 2010; 16:1088-1095.
14. Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS: Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 2002; 22:3251-3261.
15. Sen S, Duman R, Sanacora G: Serum brain-derived neurotrophic factor, depression, and an-tidepressant medications: meta-analyses and implications. Biol Psychiatry 2008; 64: 527-532.
16. APA: Practice Guideline for the Treatment of Patients with Major Depressive Disorder, ed 3. Arlington, American Psychiatric Association. 2010, pp 1-152.
17. Altar CA, Whitehead RE, Chen R, Wortwein G, Madsen TM: Effects of electrocon-vulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain. Biol Psychiatry 2003; 54: 703-709.
18. Rosa DV, Souza RP, Souza BR, Motta BS, Caetano F, Jornada LK, Feier G, Jeromin A, Gomez MV, Quevedo J, Romano-Silva MA: NCS-1 expression in rat brain after electro-convulsive stimulation. Neurochem Res 2007; 32:81-85.
19. Rosa DV, Souza RP, Souza BR, Motta BS, Caetano F, Jornada LK, Feier G, Gomez MV, Quevedo J, Romano-Silva MA: DARPP-32 expression in rat brain after electroconvulsive stimulation. Brain Res 2007; 1179:35-41.
20. Okamoto T, Yoshimura R, Ikenouchi-Sugita A, Hori H, Umene-Nakano W, Inoue Y, Ueda N, Nakamura J: Efficacy of electroconvulsive therapy is associated with changing blood levels of homovanillic acid and brain-derived neurotrophic factor (BDNF) in refractory depressed patients: a pilot study. Prog Neuro-psychopharmacol Biol Psychiatry 2008; 32: 1185-1190.
21. Bocchio-Chiavetto L, Zanardini R, Bortolo-masi M, Abate M, Segala M, Giacopuzzi M, Riva MA, Marchina E, Pasqualetti P, Perez J, Gennarelli M: Electroconvulsive therapy (ECT) increases serum brain derived neuro-trophic factor (BDNF) in drug resistant depressed patients. Eur Neuropsychopharmacol 2006; 16:620-624.
22. Marano CM, Phatak P, Vemulapalli UR, Sasan A, Nalbandyan MR, Ramanujam S, Soekadar S, Demosthenous M, Regenold WT: Increased plasma concentration of brain-derived neuro-trophic factor with electroconvulsive therapy: a pilot study in patients with major depression. J Clin Psychiatry 2007; 68:512-517.
23. Hu Y, Yu X, Yang F, Si T, Wang W, Tan Y, Zhou D, Wang H, Chen D: The level of serum brain-derived neurotrophic factor is associated with the therapeutic efficacy of modified electroconvulsive therapy in Chinese patients with depression. J ECT 2010; 26:121-125.
24. Piccinni A, Del Debbio A, Medda P, Bianchi C, Roncaglia I, Veltri A, Zanello S, Massimet-ti E, Origlia N, Domenici L, Marazziti D, Dell'Osso L: Plasma brain-derived neuro-trophic factor in treatment-resistant depressed patients receiving electroconvulsive therapy. Eur Neuropsychopharmacol 2009; 19:349-355.
25. Fernandes B, Gama CS, Massuda R, Torres M, Camargo D, Kunz M, Belmonte-de-Abreu PS, Kapczinski F, de Almeida Fleck MP, Ines Lo-bato M: Serum brain-derived neurotrophic factor (BDNF) is not associated with response to electroconvulsive therapy (ECT): a pilot study in drug resistant depressed patients. Neurosci Lett 2009; 453:195-198.
26. Gedge L, Beaudoin A, Lazowski L, du Toit R, Jokic R, Milev R: Effects of electroconvulsive therapy and repetitive transcranial magnetic stimulation on serum brain-derived neuro-trophic factor levels in patients with depression. Front Psychiatry 2012; 3:12.
27. Gronli O, Stensland GO, Wynn R, Olstad R: Neurotrophic factors in serum following ECT: a pilot study. World J Biol Psychiatry 2009; 10:295-301.
28. APA: Structured clinical interview for DSM-IV. Washington, American Psychiatric Press, 1994.
29. Souery D, Amsterdam J, de Montigny C, Lec-rubier Y, Montgomery S, Lipp O, Racagni G, Zohar J, Mendlewicz J: Treatment resistant depression: methodological overview and operational criteria. Eur Neuropsychopharma-col 1999; 9:83-91.
30. Pacchiarotti I, Mazzarini L, Colom F, Sanchez-Moreno J, Girardi P, Kotzalidis GD, Vieta E: Treatment-resistant bipolar depression: towards a new definition. Acta Psychiatr Scand 2009; 120:429-440.
31. Thase ME, Rush AJ: When at first you don't succeed: sequential strategies for antidepres-sant nonresponders. J Clin Psychiatry 1997; 58(suppl 13):23-29.
32. Hamilton M: A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62.
33. Guy W: Ecdeu Assessment Manual for Psy-chopharmacology. DHEW Publication 76338. Washington, National Institute of Mental Health, 1976.
34. American Psychiatric Association Committee on Electroconvulsive Therapy, Weiner RD (eds): The Practice of Electroconvulsive Therapy: Recommendations for Treatment, Training, and Privileging: A Task Force Report of the American Psychiatric Association, ed 2. Washington, American Psychiatric Association, 2001.
35. TM System IV, ed 7. Lake Bluff, Somatics Inc, 2002.
36. Petrides G, Fink M: The 'half-age' stimulation strategy for ECT dosing. Convuls Ther 1996; 12:138-146.
37. Vickers AJ: The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study. BMC Med Res Methodol 2001; 1:6.
38. Lommatzsch M, Zingler D, Schuhbaeck K, Schloetcke K, Zingler C, Schuff-Werner P, Virchow JC: The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiol Aging 2005; 26:115-123.
39. Thase ME: Treatment of severe depression. J Clin Psychiatry 2000; 61(suppl 1):17-25.
40. Gonul AS, Akdeniz F, Taneli F, Donat O, Eker C, Vahip S: Effect of treatment on serum brain-derived neurotrophic factor levels in depressed patients. Eur Arch Psychiatry Clin Neurosci 2005; 255:381-386.
41. Scott A: Electroconvulsive therapy and brain-derived neurotrophic factor. J ECT 2011; 27: 92, author reply 92-93.
42. Trajkovska V, Marcussen AB, Vinberg M, Hartvig P, Aznar S, Knudsen GM: Measurements of brain-derived neurotrophic factor: methodological aspects and demographical data. Brain Res Bull 2007; 73:143-149.
43. Brunoni AR, Lopes M, Fregni F: A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol 2008; 11:1169-1180.
44. Piccinni A, Marazziti D, Catena M, Domenici L, Del Debbio A, Bianchi C, Mannari C, Martini C, Da Pozzo E, Schiavi E, Mariotti A, Roncaglia I, Palla A, Consoli G, Giovannini L, Massimetti G, Dell'Osso L: Plasma and serum brain-derived neurotrophic factor (BDNF) in depressed patients during 1 year of antidepressant treatments. J Affect Disord 2008; 105: 279-283.
45. Piccinni A, Marazziti D, Del Debbio A, Bian-chi C, Roncaglia I, Mannari C, Origlia N, Catena Dell'Osso M, Massimetti G, Domenici L, Dell'Osso L: Diurnal variation of plasma brain-derived neurotrophic factor (BDNF) in humans: an analysis of sex differences. Chro-nobiol Int 2008; 25:819-826.
46. Yoshimura R, Ikenouchi-Sugita A, Hori H, Umene-Nakano W, Katsuki A, Hayashi K, Ueda N, Nakamura J: Adding a low dose atypical antipsychotic drug to an antidepressant induced a rapid increase of plasma brain-derived neurotrophic factor levels in patients with treatment-resistant depression. Prog Neuropsychopharmacol Biol Psychiatry 2010; 34:308-312.
47. Karege F, Schwald M, Cisse M: Postnatal developmental profile of brain-derived neuro-trophic factor in rat brain and platelets. Neu-rosci Lett 2002; 328:261-264.
48. Blier P, Ward HE, Tremblay P, Laberge L, Hebert C, Bergeron R: Combination of antide-pressant medications from treatment initiation for major depressive disorder: a doubleblind randomized study. Am J Psychiatry 2010; 167:281-288.