Preclinical investigations for thrombectomy devices-does it translate to humans?

Stroke

Volumn 44, Issue SUPPL. 1, 2013, Pages

  Gounis, Matthew J ^a   Wakhloo, Ajay K ^a   Chueh, Ju Yu ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Acute ischemic stroke; Clot; Embolic shower; Preclinical modeling; Recanalization; Thrombectomy

Indexed keywords

BASILAR ARTERY; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN CIRCULUS ARTERIOSUS; BRAIN ISCHEMIA; CONFERENCE PAPER; DEVICE SAFETY; EXPERIMENTAL MODEL; HEMODYNAMICS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MECHANICAL THROMBECTOMY; MEDICAL DEVICE; MICROEMBOLISM; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; RECANALIZATION; REPRODUCIBILITY;

ACUTE ISCHEMIC STROKE; CLOT; EMBOLIC SHOWER; PRECLINICAL MODELING; RECANALIZATION; THROMBECTOMY;

ANGIOGRAPHY, DIGITAL SUBTRACTION; ANIMALS; CEREBRAL ANGIOGRAPHY; CEREBROVASCULAR CIRCULATION; DEVICE APPROVAL; DISEASE MODELS, ANIMAL; DOGS; FEMALE; HUMANS; MALE; MICROSCOPY, ELECTRON, SCANNING; MODELS, ANATOMIC; SAFETY; STROKE; THROMBECTOMY; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 84880260568     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.000692     Document Type: Conference Paper

References (24)

1. Mehra M, Henninger N, Hirsch JA, Chueh J, Wakhloo AK, Gounis MJ. Preclinical acute ischemic stroke modeling. J Neurointerv Surg. 2012;4:307-313.
2. Gralla J, Schroth G, Remonda L, Fleischmann A, Fandino J, Slotboom J, et al. A dedicated animal model for mechanical thrombectomy in acute stroke. AJNR Am J Neuroradiol. 2006;27:1357-1361.
3. Jahan R. Solitaire flow-restoration device for treatment of acute ischemic stroke: safety and recanalization efficacy study in a swine vessel occlusion model. AJNR Am J Neuroradiol. 2010;31:1938-1943.
4. Nogueira RG, Levy EI, Gounis M, Siddiqui AH. The Trevo device: preclinical data of a novel stroke thrombectomy device in two different animal models of arterial thrombo-occlusive disease. J Neurointerv Surg. 2012;4:295-300.
5. Wakhloo AK, Gounis MJ. Retrievable closed cell intracranial stent for foreign body and clot removal. Neurosurgery. 2008;62(5 suppl 2):ONS390-ONS393; discussion ONS393.
6. Levy EI, Sauvageau E, Hanel RA, Parikh R, Hopkins LN. Self-expanding versus balloon-mounted stents for vessel recanalization following embolic occlusion in the canine model: technical feasibility study. AJNR Am J Neuroradiol. 2006;27:2069-2072.
7. Chueh JY, Wakhloo AK, Gounis MJ. Effectiveness of mechanical endovascular thrombectomy in a model system of cerebrovascular occlusion. AJNR Am J Neuroradiol. 2012;33:1998-2003.
8. Gailloud P, Pray JR, Muster M, Piotin M, Fasel JH, Rüfenacht DA. An in vitro anatomic model of the human cerebral arteries with saccular arterial aneurysms. Surg Radiol Anat. 1997;19:119-121.
9. Sugiu K, Martin JB, Jean B, Gailloud P, Mandai S, Rufenacht DA. Artificial cerebral aneurysm model for medical testing, training, and research. Neurol Med Chir (Tokyo). 2003;43:69-72; discussion 73.
10. Wetzel SG, Ohta M, Handa A, Auer JM, Lylyk P, Lovblad KO, et al. From patient to model: stereolithographic modeling of the cerebral vasculature based on rotational angiography. AJNR Am J Neuroradiol. 2005;26:1425-1427.
11. Knox K, Kerber CW, Singel SA, Bailey MJ, Imbesi SG. Rapid prototyping to create vascular replicas from CT scan data: making tools to teach, rehearse, and choose treatment strategies. Catheter Cardiovasc Interv. 2005;65:47-53.
12. O'Flynn PM, O'Sullivan G, Pandit AS. Methods for three-dimensional geometric characterization of the arterial vasculature. Ann Biomed Eng. 2007;35:1368-1381.
13. Vrtovec T, Likar B, Pernus F. Quantitative analysis of spinal curvature in 3D: application to CT images of normal spine. Phys Med Biol. 2008;53:1895-1908.
14. Wood NB, Zhao SZ, Zambanini A, Jackson M, Gedroyc W, Thom SA, et al. Curvature and tortuosity of the superficial femoral artery: a possible risk factor for peripheral arterial disease. J Appl Physiol. 2006;101:1412-1418.
15. Chueh JY, Wakhloo AK, Gounis MJ. Neurovascular modeling: small-batch manufacturing of silicone vascular replicas. AJNR Am J Neuroradiol. 2009;30:1159-1164.
16. Bullitt E, Muller KE, Jung I, Lin W, Aylward S. Analyzing attributes of vessel populations. Med Image Anal. 2005;9:39-49.
17. Waaijer A, van Leeuwen MS, van der Worp HB, Verhagen HJ, Mali WP, Velthuis BK. Anatomic variations in the circle of Willis in patients with symptomatic carotid artery stenosis assessed with multidetector row CT angiography. Cerebrovasc Dis. 2007;23:267-274.
18. Chung EM, Hague JP, Chanrion MA, Ramnarine KV, Katsogridakis E, Evans DH. Embolus trajectory through a physical replica of the major cerebral arteries. Stroke. 2010;41:647-652.
19. Chueh JY, Wakhloo AK, Hendricks GH, Silva CF, Weaver JP, Gounis MJ. Mechanical characterization of thromboemboli in acute ischemic stroke and laboratory embolus analogs. AJNR Am J Neuroradiol. 2011;32:1237-1244.
20. Levy EI, Boulos AS, Hanel RA, Tio FO, Alberico RA, Fronckowiak MD, et al. In vivo model of intracranial stent implantation: a pilot study to examine the histological response of cerebral vessels after randomized implantation of heparin-coated and uncoated endoluminal stents in a blinded fashion. J Neurosurg. 2003;98:544-553.
21. van der Bom I M J, Mehra M, Walvick RP, Chueh JY, Gounis MJ. Quantitative evaluation of c-arm CT CBV in a canine model of ischemic stroke. AJNR Am J Neuroradiol. 2012;33:353-358.
22. Ciccone A, Valvassori L, Nichelatti M, Sgoifo A, Ponzio M, Sterzi R, Boccardi E, SYNTHESIS Expansion Investigators. Endovascular treatment for acute ischemic stroke. N Engl J Med. 2013;368: 904-913.
23. Broderick JP, Palesch YY, Demchuk AM, Yeatts SD, Khatri P, Hill MD, et al. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med. 2013;368:893-903.
24. Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z, et al. A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med. 2013;368:914-23.