Safety profile of caffeine and 1,3-dimethylamylamine supplementation in healthy men

Human and Experimental Toxicology

Volumn 32, Issue 11, 2013, Pages 1126-1136

  Bloomer, Richard J ^a   Farney, T M ^a   Harvey, I C ^a   Alleman, R J ^a  

^a UNIVERSITY OF MEMPHIS   (United States)

Author keywords

caffeine; Dietary supplements; DMAA; safety

Indexed keywords

4 METHYL 2 HEXYLAMINE; ADVANCED OXIDATION PROTEIN PRODUCT; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CAFFEINE; CHOLESTEROL; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; TRIACYLGLYCEROL; TROPONIN I; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD CELL COUNT; BODY COMPOSITION; BODY MASS; BREATHING RATE; CARBON DIOXIDE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; DIET SUPPLEMENTATION; DIETARY INTAKE; ELECTROCARDIOGRAM; HEART RATE; HEMATOLOGICAL PARAMETERS; HUMAN; HUMAN EXPERIMENT; INFLAMMATION; MALE; METABOLIC PARAMETERS; NORMAL HUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; SAFETY; SYSTOLIC BLOOD PRESSURE; TOXICITY TESTING; TROLOX EQUIVALENT ANTIOXIDANT CAPACITY; URINALYSIS; URINE PH;

CAFFEINE; DIETARY SUPPLEMENTS; DMAA; SAFETY;

ADULT; AMINES; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; DIETARY SUPPLEMENTS; DRUG INTERACTIONS; HUMANS; MALE; YOUNG ADULT;

EID: 84880256208     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327113475680     Document Type: Article

References (8)

1. Li JS, Chen M, Li ZC. Identification and quantification of dimethylamylamine in geranium by liquid chromatography tandem mass spectrometry. Anal Chem Insights. 2012 ; 7: 47-58
2. Fleming H, Ranaivo P, Simone S. Analysis and confirmation of 1,3-DMAA and 1,4-DMAA in geranium plants using high-performance liquid chromatography with tandem mass spectrometry at ng/g concentrations. Anal Chem Insights. 2012 ; 7: 59-78
3. Heckman MA, Weil J, Gonzalez de Mejia E. Caffeine (1,3,7- trimethylxanthine) in foods: a comprehensive review on consumption, functionality, safety, and regulatory matters. J Food Sci. 2010 ; 75 (3). R77 - R87
4. Gee P, Jackson S, Easton J. Another bitter pill: a case of toxicity from DMAA party pills. N Z Med J. 2010 ; 123 (1327). 124-127
5. Gee P, Tallon C, Long N, Moore G, Boet R, Jackson S. Use of recreational drug 1,3-dimethylethylamine (DMAA) associated with cerebral hemorrhage. Ann Emerg Med. 2012 ; 60 (4). 431-434
6. Bloomer RJ, Harvey IC, Farney TM, Bell ZW, Canale RE. Effects of 1,3-dimethylamylamine and caffeine alone or in combination on heart rate and blood pressure in healthy men and women. Phys Sportsmed. 2011 ; 39 (3). 111-120
7. McCarthy C. Biochemical and anthropometric effects of a weight loss dietary supplement in healthy men and women. Nut Metab Insights. 2012 ; 5: 13-22
8. Whitehead PN, Schilling BK, Farney TM, Bloomer RJ. Impact of a dietary supplement containing 1,3-dimethylamylamine on blood pressure and bloodborne markers of health: a 10-week intervention study. Nut Metab Insights. 2012 ; 5: 33-39