Effect of simvastatin on retinal vascular caliber: The Age-Related Maculopathy Statin Study

Acta Ophthalmologica

Volumn 91, Issue 5, 2013, Pages

  Sasaki, Mariko ^a,b   Gan, Wei Lin ^a,c   Kawasaki, Ryo ^a,d   Hodgson, Lauren ^a   Lee, Kim Yu ^a   Wong, Tien Yin ^a,e   Lamoureux, Ecosse ^a,e   Robman, Liubov ^a   Guymer, Robyn ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b KEIO UNIVERSITY   (Japan)

^c Western Hospital   (Australia)

^d YAMAGATA UNIVERSITY   (Japan)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; PLACEBO; SIMVASTATIN;

BLOOD VESSEL DIAMETER; CARDIOVASCULAR RISK; CELL FUNCTION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE COURSE; DRUG ACTIVITY; ENDOTHELIUM; FOLLOW UP; HUMAN; INFLAMMATION; LETTER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RETINA MACULA AGE RELATED DEGENERATION; VASODILATATION;

FOLLOW-UP STUDIES; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MACULAR DEGENERATION; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RETINAL VESSELS; SIMVASTATIN;

EID: 84880252048     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/aos.12114     Document Type: Letter

References (5)

1. Antonopoulos AS, Margaritis M, Lee R, Channon K, &, Antoniades C, (2012): Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials. Curr Pharm Des 18: 1519-1530.
2. Guymer RH, Dimitrov PN, Varsamidis M, Lim LL, Baird PN, Vingrys AJ, &, Robman L, (2008): Can HMG Co-A reductase inhibitors ("statins") slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS). Clin Interv Aging 3: 581-593.
3. Nagaoka T, Takahashi A, Sato E, Izumi N, Hein TW, Kuo L, &, Yoshida A, (2006): Effect of systemic administration of simvastatin on retinal circulation. Arch Ophthalmol 124: 665-670.
4. Sun C, Wang JJ, Mackey DA, &, Wong TY, (2009): Retinal vascular caliber: systemic, environmental, and genetic associations. Surv Ophthalmol 54: 74-95.
5. Terai N, Spoerl E, Fischer S, Hornykewycz K, Haustein M, Haentzschel J, &, Pillunat LE, (2011): Statins affect ocular microcirculation in patients with hypercholesterolaemia. Acta Ophthalmol 89: e500-e504.