The basic helix-loop-helix (bHLH) proteins in breast cancer progression

Medical Oncology

Volumn 30, Issue 3, 2013, Pages

  Kabir, Nuzhat N ^a   Rönnstrand, Lars ^b   Kazi, Julhash U ^a,b  

^a KN Biomedical Research Institute   (Bangladesh)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN;

BREAST CANCER; CANCER GROWTH; CELL DIFFERENTIATION; DNA BINDING; GENE CONTROL; GENE EXPRESSION; HUMAN GENOME; LETTER; MUSCLE DEVELOPMENT; PRIORITY JOURNAL; APOPTOSIS; BREAST TUMOR; CARCINOGENESIS; CELL PROLIFERATION; DISEASE COURSE; FEMALE; GENETICS; HUMAN; PATHOLOGY;

APOPTOSIS; BREAST NEOPLASMS; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DISEASE PROGRESSION; FEMALE; HELIX-LOOP-HELIX MOTIFS; HUMANS;

EID: 84880212848     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-013-0666-9     Document Type: Letter

References (12)

1. Kabir NN, Hossain MI, Kazi JU. Comparative studies on human and rat basic helix-loop-helix proteins. Asian J Biol Sci. 2011;4(8):601-8. doi:10.3923/ajbs.2011.601.608.
2. Jones S. An overview of the basic helix-loop-helix proteins. Genome Biol. 2004;5(6):226. doi:10.1186/gb-2004-5-6-226.
3. Desprez PY, Sumida T, Coppe JP. Helix-loop-helix proteins in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia. 2003;8(2):225-39.
4. Kazi JU, Ronnstrand L. Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling. Mol oncol. 2013;7(3):693-703. doi:10.1016/j. molonc.2013.02.020.
5. Kabir NN, Ronnstrand L, Kazi JU. Protein kinase C expression is deregulated in chronic lymphocytic leukemia. Leuk Lymphoma. 2013;. doi:10.3109/10428194.2013.769220.
6. Kabir NN, Ronnstrand L, Kazi JU. Deregulation of protein phosphatase expression in acute myeloid leukemia. Med Oncol. 2013;30(2):517. doi:10.1007/s12032-013-0517-8.
7. Kazi JU, Sun J, Phung B, Zadjali F, Flores-Morales A, Ronnstrand L. Suppressor of cytokine signaling 6 (SOCS6) negatively regulates FLT3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of FLT3. J Biol Chem. 2012;287(43):36509-17. doi:10.1074/jbc.M112.376111.
8. Kazi JU, Ronnstrand L. FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia. Mol Oncol. 2013;7(3): 402-18. doi:10.1016/j.molonc.2012.11.003.
9. Kazi JU, Ronnstrand L. Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling. PloS One. 2012;7(12):e53509. doi:10.1371/journal.pone.0053509.
10. Wu Y, Sato F, Bhawal UK, Kawamoto T, Fujimoto K, Noshiro M, Morohashi S, Kato Y, Kijima H. Basic helix-loop-helix transcription factors DEC1 and DEC2 regulate the paclitaxelinduced apoptotic pathway of MCF-7 human breast cancer cells. Int J Mol Med. 2011;27(4):491-5. doi:10.3892/ijmm.2011.617.
11. Liu Y, Sato F, Kawamoto T, Fujimoto K, Morohashi S, Akasaka H, Kondo J, Wu Y, Noshiro M, Kato Y, Kijima H. Anti-apoptotic effect of the basic helix-loop-helix (bHLH) transcription factor DEC2 in human breast cancer cells. Genes Cells. 2010;15(4):315-25. doi:10.1111/j.1365-2443.2010.01381.x.
12. Swarbrick A, Akerfeldt MC, Lee CS, Sergio CM, Caldon CE, Hunter LJ, Sutherland RL, Musgrove EA. Regulation of cyclin expression and cell cycle progression in breast epithelial cells by the helix-loop-helix protein Id1. Oncogene. 2005;24(3):381-9. doi:10.1038/sj.onc.1208188.