Lack of both α2-antiplasmin and plasminogen activator inhibitor type-1 induces high IgE production

Life Sciences

Volumn 93, Issue 2-3, 2013, Pages 89-95

  Okada, Kiyotaka ^a   Ueshima, Shigeru ^a   Kawao, Naoyuki ^a   Yano, Masato ^a   Tamura, Yukinori ^a   Tanaka, Masaki ^a   Sakamoto, Akemi ^b   Hatano, Masahiko ^b   Arima, Masafumi ^b   Miyata, Seiji ^c   Nagai, Nobuo ^d   Tokuhisa, Takeshi ^b   Matsuo, Osamu ^a  

^a KINKI UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^d NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

2 AP; Bone marrow cells; Gene deficient mice; IgE regulation; PAI 1

Indexed keywords

ALPHA 2 ANTIPLASMIN; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CELL PROLIFERATION; CONTROLLED STUDY; FIBRINOLYSIS; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; KIDNEY PARENCHYMA; LUNG PARENCHYMA; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RADIATION DOSE; SPLEEN;

Α(2)-AP; BONE MARROW CELLS; GENE DEFICIENT MICE; IGE REGULATION; PAI-1;

AGE FACTORS; ALPHA-2-ANTIPLASMIN; ANIMALS; BONE MARROW TRANSPLANTATION; CYTOKINES; FIBRINOLYSIS; IMMUNOGLOBULIN E; KIDNEY; LIVER; LYMPHOCYTES; MICE; MICE, KNOCKOUT; PLASMINOGEN ACTIVATOR INHIBITOR 1; SPLEEN;

EID: 84880201154     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.05.023     Document Type: Article

References (24)

1. N. Aoki, H. Saito, T. Kamiya, K. Koie, Y. Sakata, and M. Kobakura Congenital deficiency of a2-plasmin inhibitor associated with severe hemorrhagic tendency J Clin Invest 63 1979 877 884
2. G.J. Bhat, J.J. Gunaje, and S. Idell Urokinase-type plasminogen activator induces tyrosine phosphorylation of a 78-kDa protein in H-157 cells Am J Physiol 277 1999 L301 L309
3. P. Carmeliet, and D. Collen Development and disease in proteinase-deficient mice role of the plasminogen, matrix metalloproteinase and coagulation system Thromb Res 91 1998 255 285
4. P. Carmeliet, L. Kieckens, L. Schoonjans, B. Ream, A. van Nuffelen, and G. Prendergast Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization J Clin Invest 92 1993 2746 2755
5. Y. Chvatchko, M.H. Kosco-Vilbois, S. Herren, J. Lefort, and J.-Y. Bonnefoy Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge J Exp Med 184 1996 2353 2360
6. D. Collen Identification and some properties of a new fast-reacting plasmin inhibitor in human plasma Eur J Biochem 69 1976 209 216
7. D. Collen, and H.R. Lijnen Basic and clinical aspects of fibrinolysis and thrombolysis Blood 78 1991 3114 3124
8. M. Dewerchin, D. Collen, and H.R. Lijnen Enhanced fibrinolytic potential in mice with combined homozygous deficiency of alpha2-antiplasmin and PAI-1 Thromb Haemost 86 2001 640 646
9. D.M. Dupont, J.B. Madsen, T. Kristensen, J.S. Bodker, G.E. Blouse, and T. Wind Biochemical properties of plasminogen activator inhibitor-1 Front Biosci 14 2009 1337 1361
10. E.C. Flood, and K.A. Hajjar The annexin A2 system and vascular homeostasis Vascul Pharmacol 54 2011 59 67
11. H. Fukao, S. Ueshima, K. Okada, and O. Matsuo The role of the pericellular fibrinolytic system in angiogenesis Jpn J Physiol 47 1997 161 171
12. R. Goldsby, T.J. Kindt, B.A. Osborne, and K. Janis Cells and organs of the immune system (Chapter 2) Immunology 5th ed. 2003 WH Freeman and Company New York 24 56
13. Y. Gong, E. Hart, A. Shchurin, and J. Hoover-Plow Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice J Clin Invest 118 2008 3012 3024
14. Y. Kanno, K. Hirade, A. Ishisaki, K. Nakajima, H. Suga, and T. Into Lack of alpha2-antiplasmin improves cutaneous wound healing via over-released vascular endothelial growth factor-induced angiogenesis in wound lesions J Thromb Haemost 4 2006 1602 1610
15. Y. Kanno, E. Kawashita, M. Minamida, A. Kaneiwa, K. Okada, and S. Ueshima Alpha2-antiplasmin is associated with the progression of fibrosis Am J Pathol 176 2010 238 245
16. H.R. Lijnen, K. Okada, O. Matsuo, D. Collen, and M. Dewerchin Alpha2-antiplasmin gene deficiency in mice is associated with enhanced fibrinolytic potential without overt bleeding Blood 93 1999 2274 2281
17. O. Matsuo, T. Sakai, H. Bando, K. Okada, S. Nakajima, and O. Takagi Plasminogen activator in bronchoalveolar fluid Haemostasis 16 1986 43 50
18. R. Mehta, and A.D. Shapiro Plasminogen activator inhibitor type 1 deficiency Haemophilia 14 2008 1255 1260
19. M.E. Meltzer, T. Lisman, P.G. de Groot, J.C. Meijers, S. le Cessie, and C.J. Doggen Venous thrombosis risk associated with plasma hypofibrinolysis is explained by elevated plasma levels of TAFI and PAI-1 Blood 116 2010 113 121
20. C.K. Oh, B. Ariue, R.F. Alban, B. Shaw, and S.H. Cho PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model Biochem Biophys Res Commun 294 2002 1155 1160
21. T. Sejima, S. Madoiwa, J. Mimuro, T. Sugo, T. Ishida, and K. Ichimura Expression profiles of fibrinolytic components in nasal mucosa Histochem Cell Biol 122 2004 61 73
22. T. Sejima, S. Madoiwa, J. Mimuro, T. Sugo, K. Okada, and S. Ueshima Protection of plasminogen activator inhibitor-1-deficient mice from nasal allergy J Immunol 174 2005 8135 8143
23. H.W. Smith, and C.J. Marshall Regulation of cell signaling by uPAR Nat Rev Mol Cell Biol 11 2010 23 36
24. M. Tanaka, K. Okada, S. Ueshima, M. Imano, H. Ohyanagi, and P. Carmeliet Impaired liver regeneration after partial hepatectomy in plasminogen deficient mice Fibrinolysis Proteolysis 15 2001 2 8 Technology Technology Technology Technology