Effects of diquafosol tetrasodium administration on visual function in short break-up time dry eye

Journal of Ocular Pharmacology and Therapeutics

Volumn 29, Issue 6, 2013, Pages 595-603

  Kaido, Minako ^a,b   Uchino, Miki ^c   Kojima, Takashi ^a   Dogru, Murat ^a   Tsubota, Kazuo ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Wada Eye Clinic   (Japan)

^c Ohtsuka Ryougoku Clinic   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIQUAFOSOL;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; DRY EYE; FEMALE; HUMAN; MALE; SYMPTOMATOLOGY; TEAR FILM; VISION; VISUAL ACUITY;

ADULT; DRY EYE SYNDROMES; FEMALE; HUMANS; MALE; MIDDLE AGED; OPHTHALMIC SOLUTIONS; OPTOMETRY; POLYPHOSPHATES; PURINERGIC P2Y RECEPTOR AGONISTS; QUESTIONNAIRES; TEARS; TIME FACTORS; TREATMENT OUTCOME; URACIL NUCLEOTIDES; VISUAL ACUITY;

EID: 84880199833     PISSN: 10807683     EISSN: 15577732     Source Type: Journal    
DOI: 10.1089/jop.2012.0246     Document Type: Article

References (48)

1. Watanabe, H. Significance of mucin on the ocular surface. Cornea 21 (2 Suppl 1):S17-S22, 2002.
2. Gipson, I.K., and Arqueso, P. Role of mucins in the function of the corneal and conjunctival epithelia. Int. Rev. Cytol. 231:1-49, 2003.
3. Jumblatt, M.M., McKenzie, R.W., and Jumblatt, J.E. MUC5AC mucin is a component of the human precorneal tear film. Invest. Ophthalmol. Vis. Sci. 40:43-49, 1999.
4. Govindarajan, B., and Gipson, I.K. Membrane-tethered mucins have multiple functions on the ocular surface. Exp. Eye Res. 90:655-663, 2010.
5. Tseng, S.C., Hirst, L.W., Maumenee, A.E., Kenyon, K.R., Sun, T.T., and Green, W.R. Possible mechanisms for the loss of goblet cells in mucin-deficient disorders. Ophthalmology 91:545-552, 1984.
6. Pflugfelder, S.C., Tseng, S.V., Yoshino, K., Monroy, D., Felix, C., and Reis, B.L. Correlation of goblet cell density and mucosal epithelial membrane mucin expression with roseBengal staining in patients with ocular irritation. Ophthalmology 104:223-235, 1997.
7. Argueso, P., Balaram, M., Spurr-Michaud, S., Keutmann, H.T., Dana, M.R., and Gipson, I.K. Decreased levels of the goblet cell mucin MUC5AC in tears of patients with Sjogren syndrome. Invest. Ophthalmol. Vis. Sci. 43:1004-1011, 2002.
8. Toda, I., Fumishima, H., and Tsubota, K. Ocular fatigue is a major symptom of dry eye. Acta. Ophthalmologica. 71:347- 352, 1993.
9. Toda, I, Shimazaki, J., and Tsubota, K., Dry eye with only decreased tear break-up time is sometimes associated with allergic conjunctivitis. Ophthalmology 102:302-309, 1995.
10. Montes-Mico, R., Caliz, A., and Alio, J.L. Changes in ocular aberrations after instillation of artificial tears in dry-eye patients. J. Cataract. Refract. Surg. 30:1649-1652, 2004.
11. Ridder, W.H., 3rd, Tomlinson, A., and Paugh, J. Effect of artificial tears on visual performance in subjects with dry eye. Optom. Vis. Sci. 2005;82:835-842.
12. Goto, E., Ishida, R., Kaido, M., et al. Optical aberrations and visual disturbances associated with dry eye. Ocul. Surf. 4:207-213, 2006 Review
13. Tong, L., Waduthantri, S., Wong, T.Y., et al. Impact of symptomatic dry eye on vision related daily activities: the Singapore Malay Eye study. Eye (Lond). 24:1486-1491, 2010.
14. Walker, P.M., Lone, K.J., Ousler, G.W., 3rd, and Abelson, M.B. Diurnal variation of visual function and the signs and symptoms of dry eye. Cornea 29:607-612, 2010.
15. Ridder, W.H., 3rd, Tomlinson, A., Huang, J.F., and Li, J. Impaired visual performance in patients with dry eye. Ocul. Surf. 9:42-55, 2011
16. Rieger, G. The importance of the precorneal tear film for the quality of optical imaging. Br. J. Ophthalmol. 76:157-158, 1992.
17. Tutt, R., Bradley, A., Befley, C., and Thibos, L.N. Optical and visual impact of tear break-up in human eyes. Invest. Ophthalmol. Vis. Sci. 41;4117-4123, 2000.
18. Nemeth, J., Erdelyi, B., and Csakany, B. Corneal topography changes after a 15 second pause in blinking. J. Cataract. Refract. Surg. 27:589-592, 2001.
19. Buehren, T., Collins, M.J., Iskander, D.R., Davis, B., and Lingelbach, B. The stability of corneal topography in the post-blink interval. Cornea 20:826-833, 2001
20. Nemeth, J. Erdelyi, B., Csakany, B., et al. High-speed videotopographic measurement of tear film bild-up time. Invest. Ophthalmol. Vis. Sci. 43:1783-1790, 2002
21. Koh, S. Maeda, N., Kuroda, T., et al. Effect of tear film breakup on higher-order aberrations measured with wavefront sensor. Am. J. Ophthalmol. 134:115-117, 2002.
22. Goto, T., Zhen, X., Klyce, S.D., et al. A new method for tear film stability analysis using videokeratography. Am. J. Ophthalmol. 135:607-612, 2003.
23. Bron, A.J., Tifffany, J.M., Gouveia, S.M., Yokoi, N., Voon, L.W. Functional aspects of the tear film lipid layer. Exp. Eye Res. 78:347-360, 2004
24. Yokoi, N., Yamada, H., Mizukusa, Y., et al. Rheology of tear film lipid layer spread in normal and aqueous tear deficient dry eyes. Invest. Ophthalmol. Vis. Sci. 49:5319-5324, 2008.
25. Liu, Z., and Pflugfelder, S.C. Corneal surface regularity and the effect of artificial tears in aqueous tear deficiency. Ophthalmology 106:939-943, 1999.
26. Ozkan, Y., Bozkurt, B., Gedik, S., Irkec, M., and Orhan, M. Corneal topographical study of the effect of lacrimal punctum occlusion on corneal surface regularity in dry eye patients. Eur. J. Ophthalmol. 11:116-119, 2001.
27. Goto, E., Yagi, Y., Matsumoto, Y., et al. Impaired functional visual acuity of dry eye patients. Am. J. Ophthalmol. 133:181- 186, 2002.
28. Kojima, T., Ishida, R., Dogru, M., et al. A new noninvasive tear stability analysis system for the assessment of dry eye. Invest. Ophthalmol. Vis. Sci. 45:1369-1374, 2004.
29. Montes-Mico, R., Caliz, A., and Alio, J.L. Wavefront analysis of higher order aberrations in dry eye patients. J. Refract. Surg. 20:243-247, 2004.
30. Goto, E., Yagi, Y., Kaido, M., et al. Improved functional visual acuity after punctal occlusion in dry eye patients. Am. J. Ophthalmol. 135:704-705, 2003.
31. Ishida, R., Kojima, T., Dogru, M., et al. The application of a new continuous functional visual acuity measurement system in dry eye syndromes. Am. J. Opthalmol. 139:253-258, 2005.
32. Kaido, M., Dogru, M., Ishida, R., and Tsubota, K. Concept of functional visual acuity and its applications. Cornea 26 (9 Suppl 1):S29-S35, 2007 Review.
33. Kaido, M., Ishida, R., Dogru, M., and Tsubota, K. The relation of functional visual acuity measurement methodology with tear functions and ocular surface status. Jpn. J. Ophthalmol. 55:451-459, 2011.
34. Kaido, M., Matsumoto, Y., Shigeno, Y., Ishida, R., Dogru, M., and Tsubota, K. Corneal fluorescein staining is correlated with visual function in dry eye patients. Invest. Ophthalmol. Vis. Sci. 52:9516-9522, 2011.
35. Kaido, M., Yamada, M., Sotozono, C., et al. The relation between visual performance and clinical ocular manifestations in Stevens-Johnson syndrome. Am. J. Ophthalmol. 154:499-519, 2012.
36. Fujihara, T., Murakami, T., Nagano, T., et al. INS365 suppresses loss of corneal epithelial integrity by secretion of mucin-like glucoprotein in a rabbit short-term dry eye model. J. Ocul. Pharmacol. Ther. 18:363-370, 2002.
37. Fujihara, T., Murakami, T., Fujita, H., et al. Improvement of corneal barrier function by the P2S(2) agonist INS365 in a rat dry eye model. Invest. Ophthalmol. Vis. Sci. 42:96-100, 2001.
38. Takaoka-Shichijo, Y., and Nakamura, M. Stimulatory effect of diquafosol tetrasodium on the expression of membranebinding mucin genes in cultured human corneal epithelial cells. J. Eye 28:425-429, 2011.
39. Shimazaki, J. Definition and diagnosis of dry eye 2006. J. Eye 24: 181-184, 2007. [In Japanese]
40. Kaido, M., Dogru, M., Yamada, M., et al. Funtional visual acuity in Stevens-Johnson syndrome. Am. J. Ophthalmol. 142:917-922, 2006
41. Kaido, M., Toda, I., Ishida, R., Konagai, M., Dogru, M., and Tsubota, K. Age-related changes in functional visual acuity in healthy individuals. Jpn. J. Ophthalmol. 55:183- 189, 2011.
42. Yerxa, B.R., Douglass, J.G., Elena, P.P., et al. Potency and duration of action of synthetic P2Y2 receptor agonists on Schirmer scores in rabbits. Adv. Exp. Med. Biol. 506 (Pt A):261-265, 2002.
43. Murakami, T., Fujita, H., Fujihara, T., et al. Novel noninvasive sensitive determination of tear volume changes in normal cats. Ophthalmic. Res. 34:371-374, 2002.
44. Sullivan, B.D., Whitmer, D., Nichols, K.K., et al. An objective approach to dry eye desease severity. Invest. Ophthalmol. Vis. Sci. 51:6125-6130, 2010.
45. Lemp, M.A., Bron, A.J., Baudouinm, C., et al. Tear osmolarity in the diagnosis and management of dry eye disease. Am. J. Opthalmol. 151:792-798, 2011.
46. Sullivan, B.D., Crews, L.A., Sonmez, B., et al. Clinical utility of objective tests for dry eye disease: variability over time and implications for clinical trials and disease management. Cornea 31:1000-1001, 2012.
47. Kaido, M., Ishida, R., Dogru, M., Tamaoki, T., and Tsubota, K. Efficacy of punctum plug treatment in short break-up time dry eye. Optom. Vis. Sci. 85:758-763, 2008.
48. Nilforoushan, M.R., Latkany, R.A., and Speaker, M.G. Effect of artificial tears on visual acuity. Am. J. Ophthalmol. 140:830- 835, 2005