메뉴 건너뛰기




Volumn 305, Issue 2, 2013, Pages

High glucose levels reduce fatty acid oxidation and increase triglyceride accumulation in human placenta

Author keywords

Carnitine palmitoyltransferase I; De novo fatty acid synthesis; Esterification of fatty acids; Fatty acid oxidation; Gestational diabetes mellitus; Hyperglycemia; Placenta; Triglycerides

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CARNITINE PALMITOYLTRANSFERASE; ETOMOXIR; GLUCOSE; TRIACYLGLYCEROL;

EID: 84880174455     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00032.2013     Document Type: Article
Times cited : (70)

References (42)
  • 1
    • 0018602014 scopus 로고
    • Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
    • No authors listed. National Diabetes Data Group
    • No authors listed. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. National Diabetes Data Group. Diabetes 28: 1039-1057, 1979.
    • (1979) Diabetes , vol.28 , pp. 1039-1057
  • 2
    • 84855771388 scopus 로고    scopus 로고
    • Decreased mitochondrial fatty acid oxidation in placentas from women with preeclampsia
    • Bartha JL, Visiedo F, Fernandez-Deudero A, Bugatto F, Perdomo G. Decreased mitochondrial fatty acid oxidation in placentas from women with preeclampsia. Placenta 33: 132-134, 2012.
    • (2012) Placenta , vol.33 , pp. 132-134
    • Bartha, J.L.1    Visiedo, F.2    Fernandez-Deudero, A.3    Bugatto, F.4    Perdomo, G.5
  • 3
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917, 1959.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 4
    • 1542673443 scopus 로고    scopus 로고
    • Expression, purification, and reconstitution of rat liver carnitine palmitoyltransferase I
    • Brown NF. Expression, purification, and reconstitution of rat liver carnitine palmitoyltransferase I. Methods Mol Biol 228: 281-301, 2003.
    • (2003) Methods Mol Biol , vol.228 , pp. 281-301
    • Brown, N.F.1
  • 5
    • 35248816945 scopus 로고    scopus 로고
    • The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes
    • Brown NF, Stefanovic-Racic M, Sipula IJ, Perdomo G. The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes. Metabolism 56: 1500-1507, 2007.
    • (2007) Metabolism , vol.56 , pp. 1500-1507
    • Brown, N.F.1    Stefanovic-Racic, M.2    Sipula, I.J.3    Perdomo, G.4
  • 6
    • 14644409707 scopus 로고    scopus 로고
    • Gestational diabetes mellitus
    • Buchanan TA, Xiang AH. Gestational diabetes mellitus. J Clin Invest 115: 485-491, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 485-491
    • Buchanan, T.A.1    Xiang, A.H.2
  • 8
    • 79958164780 scopus 로고    scopus 로고
    • Is it time to revisit the Pedersen hypothesis in the face of the obesity epidemic?
    • Catalano PM, Hauguel-De Mouzon S. Is it time to revisit the Pedersen hypothesis in the face of the obesity epidemic? Am J Obstet Gynecol 204: 479-487, 2011.
    • (2011) Am J Obstet Gynecol , vol.204 , pp. 479-487
    • Catalano, P.M.1    Hauguel-de Mouzon, S.2
  • 10
    • 49549143871 scopus 로고
    • Carbohydrate-induced lipogenesis in the human placenta of normal and diabetic pregnancies
    • Coltart TM, Bateman C. Carbohydrate-induced lipogenesis in the human placenta of normal and diabetic pregnancies. Br J Obstet Gynaecol 82: 471-475, 1975.
    • (1975) Br J Obstet Gynaecol , vol.82 , pp. 471-475
    • Coltart, T.M.1    Bateman, C.2
  • 11
    • 79952200821 scopus 로고    scopus 로고
    • New diagnostic criteria for gestational diabetes mellitus after the HAPO study. Are they valid in our environment?
    • Grupo Español de Diabetes y Embarazo
    • Corcoy R, Lumbreras B, Bartha JL, Ricart W; Grupo Español de Diabetes y Embarazo. [New diagnostic criteria for gestational diabetes mellitus after the HAPO study. Are they valid in our environment?] Endocrinol Nutr 57: 277-280, 2010.
    • (2010) Endocrinol Nutr , vol.57 , pp. 277-280
    • Corcoy, R.1    Lumbreras, B.2    Bartha, J.L.3    Ricart, W.4
  • 13
    • 80052093505 scopus 로고    scopus 로고
    • Maternal environment and the transgenerational cycle of obesity and diabetes
    • Dabelea D, Crume T. Maternal environment and the transgenerational cycle of obesity and diabetes. Diabetes 60: 1849-1855, 2011.
    • (2011) Diabetes , vol.60 , pp. 1849-1855
    • Dabelea, D.1    Crume, T.2
  • 14
    • 0019968489 scopus 로고
    • Placental lipid and glycogen content in human and experimental diabetes mellitus
    • Diamant YZ, Metzger BE, Freinkel N, Shafrir E. Placental lipid and glycogen content in human and experimental diabetes mellitus. Am J Obstet Gynecol 144: 5-11, 1982.
    • (1982) Am J Obstet Gynecol , vol.144 , pp. 5-11
    • Diamant, Y.Z.1    Metzger, B.E.2    Freinkel, N.3    Shafrir, E.4
  • 15
    • 0019241940 scopus 로고
    • Banting Lecture 1980. Of pregnancy and progeny
    • Freinkel N. Banting Lecture 1980. Of pregnancy and progeny. Diabetes 29: 1023-1035, 1980.
    • (1980) Diabetes , vol.29 , pp. 1023-1035
    • Freinkel, N.1
  • 18
    • 63249084929 scopus 로고    scopus 로고
    • Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: Associations with neonatal anthropometrics
    • HAPO Study Cooperative Research Group
    • HAPO Study Cooperative Research Group. Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: associations with neonatal anthropometrics. Diabetes 58: 453-459, 2009.
    • (2009) Diabetes , vol.58 , pp. 453-459
  • 19
    • 0026335253 scopus 로고
    • The placenta. Not just a conduit for maternal fuels
    • HayWWJr. The placenta. Not just a conduit for maternal fuels. Diabetes 40, Suppl 2: 44-50, 1991.
    • (1991) Diabetes , vol.40 , Issue.SUPPL. 2 , pp. 44-50
    • Hay Jr., W.W.1
  • 20
    • 72949141480 scopus 로고
    • Stimulation of fatty acid synthesis by oestradiol in vitro
    • Hosoya N, Hagerman D, Villee C. Stimulation of fatty acid synthesis by oestradiol in vitro. Biochem J 76: 297-301, 1960.
    • (1960) Biochem J , vol.76 , pp. 297-301
    • Hosoya, N.1    Hagerman, D.2    Villee, C.3
  • 21
    • 0027337362 scopus 로고
    • Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucosestimulated insulin secretion. Relationship to glucose metabolism
    • Hughes SD, Quaade C, Johnson JH, Ferber S, Newgard CB. Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucosestimulated insulin secretion. Relationship to glucose metabolism. J Biol Chem 268: 15205-15212, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 15205-15212
    • Hughes, S.D.1    Quaade, C.2    Johnson, J.H.3    Ferber, S.4    Newgard, C.B.5
  • 22
    • 0035347149 scopus 로고    scopus 로고
    • Maternal serum triglyceride at 24-32 weeks' gestation and newborn weight in nondiabetic women with positive diabetic screens
    • Kitajima M, Oka S, Yasuhi I, Fukuda M, Rii Y, Ishimaru T. Maternal serum triglyceride at 24-32 weeks' gestation and newborn weight in nondiabetic women with positive diabetic screens. Obstet Gynecol 97: 776-780, 2001.
    • (2001) Obstet Gynecol , vol.97 , pp. 776-780
    • Kitajima, M.1    Oka, S.2    Yasuhi, I.3    Fukuda, M.4    Rii, Y.5    Ishimaru, T.6
  • 23
    • 0021849886 scopus 로고
    • Relationships of infant birth size to maternal lipoproteins, apoproteins, fuels, hormones, clinical chemistries, and body weight at 36 weeks gestation
    • Knopp RH, Bergelin RO, Wahl PW, Walden CE. Relationships of infant birth size to maternal lipoproteins, apoproteins, fuels, hormones, clinical chemistries, and body weight at 36 weeks gestation. Diabetes 34, Suppl 2: 71-77, 1985.
    • (1985) Diabetes , vol.34 , Issue.SUPPL. 2 , pp. 71-77
    • Knopp, R.H.1    Bergelin, R.O.2    Wahl, P.W.3    Walden, C.E.4
  • 24
    • 79951512280 scopus 로고    scopus 로고
    • Effect of IL-6 and TNF-alpha on fatty acid uptake in cultured human primary trophoblast cells
    • Lager S, Jansson N, Olsson AL, Wennergren M, Jansson T, Powell TL. Effect of IL-6 and TNF-alpha on fatty acid uptake in cultured human primary trophoblast cells. Placenta 32: 121-127, 2011.
    • (2011) Placenta , vol.32 , pp. 121-127
    • Lager, S.1    Jansson, N.2    Olsson, A.L.3    Wennergren, M.4    Jansson, T.5    Powell, T.L.6
  • 25
    • 33845579126 scopus 로고    scopus 로고
    • Placental triglyceride accumulation in maternal type 1 diabetes is associated with increased lipase gene expression
    • Lindegaard ML, Damm P, Mathiesen ER, Nielsen LB. Placental triglyceride accumulation in maternal type 1 diabetes is associated with increased lipase gene expression. J Lipid Res 47: 2581-2588, 2006.
    • (2006) J Lipid Res , vol.47 , pp. 2581-2588
    • Lindegaard, M.L.1    Damm, P.2    Mathiesen, E.R.3    Nielsen, L.B.4
  • 27
    • 78650838933 scopus 로고    scopus 로고
    • Fetal and neonatal complications of gestational diabetes: Perinatal mortality, congenital malformations, macrosomia, shoulder dystocia, birth injuries, neonatal outcomes
    • Mitanchez D. [Fetal and neonatal complications of gestational diabetes: perinatal mortality, congenital malformations, macrosomia, shoulder dystocia, birth injuries, neonatal outcomes]. J Gynecol Obstet Biol Reprod (Paris) 39: S189-199, 2010.
    • (2010) J Gynecol Obstet Biol Reprod (Paris) , vol.39
    • Mitanchez, D.1
  • 28
    • 0028864129 scopus 로고
    • Maternal serum triglyceride, glucose tolerance, and neonatal birth weight ratio in pregnancy
    • Nolan CJ, Riley SF, Sheedy MT, Walstab JE, Beischer NA. Maternal serum triglyceride, glucose tolerance, and neonatal birth weight ratio in pregnancy. Diabetes Care 18: 1550-1556, 1995.
    • (1995) Diabetes Care , vol.18 , pp. 1550-1556
    • Nolan, C.J.1    Riley, S.F.2    Sheedy, M.T.3    Walstab, J.E.4    Beischer, N.A.5
  • 31
    • 0003067559 scopus 로고
    • Weight and length at birth of infants of diabetic mothers
    • Pedersen J. Weight and length at birth of infants of diabetic mothers. Acta Endocrinol (Copenh) 16: 330-342, 1954.
    • (1954) Acta Endocrinol (Copenh) , vol.16 , pp. 330-342
    • Pedersen, J.1
  • 32
    • 3042551249 scopus 로고    scopus 로고
    • Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation
    • Perdomo G, Commerford SR, Richard AM, Adams SH, Corkey BE, O'Doherty RM, Brown NF. Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. J Biol Chem 279: 27177-27186, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 27177-27186
    • Perdomo, G.1    Commerford, S.R.2    Richard, A.M.3    Adams, S.H.4    Corkey, B.E.5    O'Doherty, R.M.6    Brown, N.F.7
  • 34
    • 67651111700 scopus 로고    scopus 로고
    • Differential regulation of genes for fetoplacental lipid pathways in pregnancy with gestational and type 1 diabetes mellitus
    • Radaelli T, Lepercq J, Varastehpour A, Basu S, Catalano PM, Hauguel-De Mouzon S. Differential regulation of genes for fetoplacental lipid pathways in pregnancy with gestational and type 1 diabetes mellitus. Am J Obstet Gynecol 201: 209. e201-209. e210, 2009.
    • (2009) Am J Obstet Gynecol , vol.201
    • Radaelli, T.1    Lepercq, J.2    Varastehpour, A.3    Basu, S.4    Catalano, P.M.5    Hauguel-de Mouzon, S.6
  • 35
    • 0345275807 scopus 로고    scopus 로고
    • Gestational diabetes induces placental genes for chronic stress and inflammatory pathways
    • Radaelli T, Varastehpour A, Catalano P, Hauguel-de Mouzon S. Gestational diabetes induces placental genes for chronic stress and inflammatory pathways. Diabetes 52: 2951-2958, 2003.
    • (2003) Diabetes , vol.52 , pp. 2951-2958
    • Radaelli, T.1    Varastehpour, A.2    Catalano, P.3    Hauguel-de Mouzon, S.4
  • 36
    • 30044452294 scopus 로고    scopus 로고
    • The pregnancies of women with Type 2 diabetes: Poor outcomes but opportunities for improvement
    • Roland JM, Murphy HR, Ball V, Northcote-Wright J, Temple RC. The pregnancies of women with Type 2 diabetes: poor outcomes but opportunities for improvement. Diabet Med 22: 1774-1777, 2005.
    • (2005) Diabet Med , vol.22 , pp. 1774-1777
    • Roland, J.M.1    Murphy, H.R.2    Ball, V.3    Northcote-Wright, J.4    Temple, R.C.5
  • 38
    • 55849144881 scopus 로고    scopus 로고
    • Maternal lipids as strong determinants of fetal environment and growth in pregnancies with gestational diabetes mellitus
    • Schaefer-Graf UM, Graf K, Kulbacka I, Kjos SL, Dudenhausen J, Vetter K, Herrera E. Maternal lipids as strong determinants of fetal environment and growth in pregnancies with gestational diabetes mellitus. Diabetes Care 31: 1858-1863, 2008.
    • (2008) Diabetes Care , vol.31 , pp. 1858-1863
    • Schaefer-Graf, U.M.1    Graf, K.2    Kulbacka, I.3    Kjos, S.L.4    Dudenhausen, J.5    Vetter, K.6    Herrera, E.7
  • 39
    • 0020027681 scopus 로고
    • Maternal-fetal fat transport versus new fat synthesis in the pregnant diabetic rat
    • Shafrir E, Khassis S. Maternal-fetal fat transport versus new fat synthesis in the pregnant diabetic rat. Diabetologia 22: 111-117, 1982.
    • (1982) Diabetologia , vol.22 , pp. 111-117
    • Shafrir, E.1    Khassis, S.2
  • 40
    • 0014710954 scopus 로고
    • The effect of insulin on glucose metabolism of the incubated human placenta
    • Szabo AJ, Grimaldi RD. The effect of insulin on glucose metabolism of the incubated human placenta. Am J Obstet Gynecol 106: 75-78, 1970.
    • (1970) Am J Obstet Gynecol , vol.106 , pp. 75-78
    • Szabo, A.J.1    Grimaldi, R.D.2
  • 41
    • 0016140475 scopus 로고
    • Placental free-fatty-acid transfer and fetal adiposetissue development: An explantation of fetal adiposity in infants of diabetic mothers
    • Szabo AJ, Szabo O. Placental free-fatty-acid transfer and fetal adiposetissue development: an explantation of fetal adiposity in infants of diabetic mothers. Lancet 2: 498-499, 1974.
    • (1974) Lancet , vol.2 , pp. 498-499
    • Szabo, A.J.1    Szabo, O.2
  • 42
    • 84855583694 scopus 로고    scopus 로고
    • Maternal diabetes in pregnancy: Early and long-term outcomes on the offspring and the concept of metabolic memory
    • Yessoufou A, Moutairou K. Maternal diabetes in pregnancy: early and long-term outcomes on the offspring and the concept of "metabolic memory". Exp Diabetes Res 2011: 218598, 2011.
    • (2011) Exp Diabetes Res , vol.2011 , pp. 218598
    • Yessoufou, A.1    Moutairou, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.