Alternate day fasting increases LDL particle size independently of dietary fat content in obese humans

European Journal of Clinical Nutrition

Volumn 67, Issue 7, 2013, Pages 783-785

  Klempel, M C ^a   Kroeger, C M ^a   Varady, K A ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

alternate day fasting; calorie restriction; dietary fat; HDL particle size; LDL particle size; weight loss

Indexed keywords

HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; BODY MASS; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; FAT CONTENT; FAT INTAKE; FEMALE; HUMAN; LIPID BLOOD LEVEL; LIPID DIET; MALE; NUTRITIONAL ASSESSMENT; OBESITY; OUTCOME ASSESSMENT; PARTICLE SIZE; RANDOMIZED CONTROLLED TRIAL; THERAPY EFFECT; TREATMENT RESPONSE; WEIGHT REDUCTION;

ADULT; BODY MASS INDEX; BODY WEIGHT; CARDIOVASCULAR DISEASES; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIET, FAT-RESTRICTED; DIET, HIGH-FAT; DIETARY FATS; FASTING; FEMALE; HUMANS; MIDDLE AGED; OBESITY; PARTICLE SIZE; RISK FACTORS; TRIGLYCERIDES;

EID: 84880135267     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2013.83     Document Type: Article

References (11)

1. Krauss RM, Blanche PJ, Rawlings RS, Fernstrom HS, Williams PT. Separate effects of reduced carbohydrate intake and weight loss on atherogenic dyslipidemia. Am J Clin Nutr 2006; 83: 1025-1031. (Pubitemid 44713100)
2. Varady KA, Bhutani S, Klempel MC, Lamarche B. Improvements in LDL particle size and distribution by short-term alternate day modified fasting in obese adults. Br J Nutr 2011; 105: 580-583.
3. Bhutani S, Klempel MC, Kroeger CM, Trepanowski JF, Varady KA. Alternate day fasting and endurance exercise combine to reduce body weight and favorably alter plasma lipids in obese humans. Obesity (Silver Spring) 2013; e-pub ahead of print 14 February 2013.
4. What we eat in America, NHANES 2007-2008, individuals 2 years and over, 1 day dietary intake data, weighted. In 2010.
5. Mifflin St MD, Jeor ST, Hill LA, Scott BJ, Daugherty SA, Koh YO. A new predictive equation for resting energy expenditure in healthy individuals. Am J Clin Nutr 1990; 51: 241-247.
6. Hoefner DM, Hodel SD, O'Brien JF, Branum EL, Sun D, Meissner I et al. Development of a rapid, quantitative method for LDL subfractionation with use of the Quantimetrix Lipoprint LDL System. Clin Chem 2001; 47: 266-274. (Pubitemid 32142925)
7. Hays JH, DiSabatino A, Gorman RT, Vincent S, Stillabower ME. Effect of a high saturated fat and no-starch diet on serum lipid subfractions in patients with documented atherosclerotic cardiovascular disease. Mayo Clin Proc 2003; 78: 1331-1336. (Pubitemid 37337777)
8. Dreon DM, Fernstrom HA, Campos H, Blanche P, Williams PT, Krauss RM. Change in dietary saturated fat intake is correlated with change in mass of large low-density-lipoprotein particles in men. Am J Clin Nutr 1998; 67: 828-836. (Pubitemid 28196655)
9. Wojczynski MK, Glasser SP, Oberman A, Kabagambe EK, Hopkins PN, Tsai MY et al. High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid-Lowering Drugs and Diet Network (GOLDN): an interventional study. Lipids Health Dis 2011; 10: 181.
10. Huffman KM, Hawk VH, Henes ST, Ocampo CI, Orenduff MC, Slentz CA et al. Exercise effects on lipids in persons with varying dietary patterns-does diet matter if they exercise?Responses in Studies of a Targeted Risk Reduction Intervention through Defined Exercise I. Am Heart J 2012; 164: 117-124.
11. Campbell SC, Moffatt RJ, Kushnick MR. Continuous and intermittent walking alters HDL(2)-C and LCATa. Atherosclerosis 2011; 218: 524-529.