Regulation of WNK4 gene transcription in the kidneys

Genetics and Molecular Research

Volumn 12, Issue 3, 2013, Pages 2332-2340

  Sun, Z J ^a   Li, Y ^a   Li, Y H ^a   Zhang, J S ^a,b   Ding, Q ^a   Li Ling, J ^b,c   Liang, Y ^a   Zhao, Y Y ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b NORTHEASTERN UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

Author keywords

Gene expression; Kidney; Promoter region; Transcription factor; WNK4

Indexed keywords

CATALASE; CIS ACTING ELEMENT; DEXAMETHASONE; MESSENGER RNA; PROTEIN KINASE WNK4;

5' UNTRANSLATED REGION; ARTICLE; BIOINFORMATICS; BLOOD PRESSURE REGULATION; COMPUTER PROGRAM; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTENSION; KIDNEY PARENCHYMA; PROMOTER REGION; REGULATORY SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; WNK4 GENE;

BASE SEQUENCE; DEXAMETHASONE; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; KIDNEY; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EID: 84880092244     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/2013.January.4.9     Document Type: Article

References (10)

1. Bielohuby M, Roemmler J, Manolopoulou J, Johnsen I, et al. (2009). Chronic growth hormone excess is associated with increased aldosterone: a study in patients with acromegaly and in growth hormone transgenic mice. Exp. Biol. Med. 234: 1002-1009.
2. Dhanasekaran N (1998). Cell signaling: an overview. Oncogene 17: 1329-1330.
3. Dhanasekaran N and Premkumar Reddy E (1998). Signaling by dual specificity kinases. Oncogene 17: 1447-1455.
4. Erlich PM, Cui J, Chazaro I, Farrer LA, et al. (2003). Genetic variants of WNK4 in whites and African Americans with hypertension. Hypertension 41: 1191-1195.
5. + secretion. Nat. Genet. 35: 372-376.
6. Kahle KT, Macgregor GG, Wilson FH, Van Hoek AN, et al. (2004). Paracellular Cl-permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension. Proc. Natl. Acad. Sci. U. S. A. 101: 14877-14882.
7. Mader S, Leroy P, Chen JY and Chambon P (1993). Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors. J. Biol. Chem. 268: 591-600.
8. Sun ZJ, Wang XN, Lu JY, Ding Q, et al. (2003). Correlation analysis between WNK4 gene and essential hypertension. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 25: 145-148.
9. Vongpatanasin W (2009). Autonomic regulation of blood pressure in menopause. Semin. Reprod. Med. 27: 338-345.
10. Yamauchi K, Rai T, Kobayashi K, Sohara E, et al. (2004). Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins. Proc. Natl. Acad. Sci. U. S. A. 101: 4690-4694.