메뉴 건너뛰기




Volumn 17, Issue 3, 2013, Pages 257-262

Efficacy and safety of ipilimumab therapy in patients with metastatic melanoma: A retrospective multicenter analysis

Author keywords

CTLA 4; Immunotherapy; Ipilimumab; Melanoma; Outcome

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IPILIMUMAB;

EID: 84880074776     PISSN: 14282526     EISSN: None     Source Type: Journal    
DOI: 10.5114/wo.2013.35785     Document Type: Article
Times cited : (19)

References (27)
  • 1
    • 36849035139 scopus 로고    scopus 로고
    • Targeting cytotoxic T-lymphocyte antigen-4 (CTLA4): A novel strategy for the treatment of melanoma and other malignancies
    • O'Day SJ, Hamid O, Urba WJ. Targeting cytotoxic T-lymphocyte antigen-4 (CTLA4): a novel strategy for the treatment of melanoma and other malignancies. Cancer 2007; 110: 2614-27.
    • (2007) Cancer , vol.110 , pp. 2614-2627
    • O'Day, S.J.1    Hamid, O.2    Urba, W.J.3
  • 2
    • 80052536175 scopus 로고    scopus 로고
    • New drugs in melanoma: It's a whole new world
    • Eggermont AM, Robert C. New drugs in melanoma: It's a whole new world. Eur J Cancer 2011; 47: 2150-7.
    • (2011) Eur J Cancer , vol.47 , pp. 2150-2157
    • Eggermont, A.M.1    Robert, C.2
  • 3
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996; 271: 1734-6.
    • (1996) Science , vol.271 , pp. 1734-1736
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 4
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res 2009; 15: 7412-0.
    • (2009) Clin Cancer Res , vol.15 , pp. 7412-7413
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3
  • 5
    • 84875881028 scopus 로고    scopus 로고
    • Ipilimumab-Progress in therapy of advanced melanoma
    • Switaj T, Wysocki P, Wojtukiewicz M, et al. Ipilimumab-Progress in therapy of advanced melanoma. Onkol Prakt Klin 2011; 7: 231-45.
    • (2011) Onkol Prakt Klin , vol.7 , pp. 231-245
    • Switaj, T.1    Wysocki, P.2    Wojtukiewicz, M.3
  • 6
    • 79953653271 scopus 로고    scopus 로고
    • Treatment and side effect management of CTLA-4 antibody therapy in metastatic melanoma
    • Kähler KC, Hauschild A. Treatment and side effect management of CTLA-4 antibody therapy in metastatic melanoma. J Dtsch Dermatol Ges 2011; 9: 277-85.
    • (2011) J Dtsch Dermatol Ges , vol.9 , pp. 277-285
    • Kähler, K.C.1    Hauschild, A.2
  • 7
    • 78449256966 scopus 로고    scopus 로고
    • Update on immunologic therapy with anti-CTLA-4 antibodies in melanoma: Identification of clinical and biological response patterns, immune-related adverse events, and their management
    • Kaehler KC, Piel S, Livingstone E, Schilling B, Hauschild A, Schadendorf D. Update on immunologic therapy with anti-CTLA-4 antibodies in melanoma: identification of clinical and biological response patterns, immune-related adverse events, and their management. Semin Oncol 2010; 37: 485-98.
    • (2010) Semin Oncol , vol.37 , pp. 485-498
    • Kaehler, K.C.1    Piel, S.2    Livingstone, E.3    Schilling, B.4    Hauschild, A.5    Schadendorf, D.6
  • 8
    • 74949143594 scopus 로고    scopus 로고
    • Final version of 2009 AJCC melanoma staging and classification
    • Balch CM, Gershenwald JE, Soong SJ, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009; 27: 6199-206.
    • (2009) J Clin Oncol , vol.27 , pp. 6199-6206
    • Balch, C.M.1    Gershenwald, J.E.2    Soong, S.J.3
  • 9
    • 0034124656 scopus 로고    scopus 로고
    • Dacarbazine-based chemotherapy for metastatic melanoma: Thirty-year experience overview
    • Serrone L, Zeuli M, Sega FM, Cognetti F. Dacarbazine-based chemotherapy for metastatic melanoma: thirty-year experience overview. J Exp Clin Cancer Res 2000; 19: 21-34.
    • (2000) J Exp Clin Cancer Res , vol.19 , pp. 21-34
    • Serrone, L.1    Zeuli, M.2    Sega, F.M.3    Cognetti, F.4
  • 10
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363: 711-23.
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 11
    • 84859393995 scopus 로고    scopus 로고
    • CTLA-4 blockade with ipilimumab: Long-term follow-up of 177 patients with metastatic melanoma
    • Prieto PA, Yang JC, Sherry RM et al. CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma. Clin Cancer Res 2012; 18: 2039-47.
    • (2012) Clin Cancer Res , vol.18 , pp. 2039-2047
    • Prieto, P.A.1    Yang, J.C.2    Sherry, R.M.3
  • 12
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011; 364: 2517-26.
    • (2011) N Engl J Med , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3
  • 13
    • 77955256254 scopus 로고    scopus 로고
    • Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: amulticenter single-arm phase II study
    • O'Day SJ, Maio M, Chiarion-Sileni V, et al. Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: amulticenter single-arm phase II study. Ann Oncol 2010; 21: 1712-7.
    • (2010) Ann Oncol , vol.21 , pp. 1712-1717
    • O'Day, S.J.1    Maio, M.2    Chiarion-Sileni, V.3
  • 14
    • 69949095926 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma
    • Weber J, Thompson JA, Hamid O, et al. A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma. Clin Cancer Res 2009; 15: 5591-8.
    • (2009) Clin Cancer Res , vol.15 , pp. 5591-5598
    • Weber, J.1    Thompson, J.A.2    Hamid, O.3
  • 15
    • 75249100054 scopus 로고    scopus 로고
    • Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, dose-ranging study
    • Wolchok JD, Neyns B, Linette G, et al. Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol 2010; 11: 155-64.
    • (2010) Lancet Oncol , vol.11 , pp. 155-164
    • Wolchok, J.D.1    Neyns, B.2    Linette, G.3
  • 16
    • 84860446616 scopus 로고    scopus 로고
    • Ipilimumab in patients with melanoma and brain metastases: An open-label, phase 2 trial
    • Margolin K, Ernstoff MS, Hamid O, et al. Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial. Lancet Oncol 2012; 13: 459-65.
    • (2012) Lancet Oncol , vol.13 , pp. 459-465
    • Margolin, K.1    Ernstoff, M.S.2    Hamid, O.3
  • 17
    • 77950258677 scopus 로고    scopus 로고
    • Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: Lymphocyte count after 2 doses correlates with survival
    • Ku GY, Yuan J, Page DB, et al. Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: lymphocyte count after 2 doses correlates with survival. Cancer 2010; 116: 1767-75.
    • (2010) Cancer , vol.116 , pp. 1767-1775
    • Ku, G.Y.1    Yuan, J.2    Page, D.B.3
  • 18
    • 77952337834 scopus 로고    scopus 로고
    • Preoperative CTLA-4 blockade: Tolerability and immune monitoring in the setting of a presurgical clinical trial
    • Carthon BC, Wolchok JD, Yuan J, et al. Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res 2010; 16: 2861-71.
    • (2010) Clin Cancer Res , vol.16 , pp. 2861-2871
    • Carthon, B.C.1    Wolchok, J.D.2    Yuan, J.3
  • 19
    • 80051694786 scopus 로고    scopus 로고
    • The ICOS/ICOSL pathway is required for optimal antitumor responses mediated by anti-CTLA-4 therapy
    • Fu T, He Q, Sharma P. The ICOS/ICOSL pathway is required for optimal antitumor responses mediated by anti-CTLA-4 therapy. Cancer Res 2011; 71: 5445-54.
    • (2011) Cancer Res , vol.71 , pp. 5445-5454
    • Fu, T.1    He, Q.2    Sharma, P.3
  • 20
    • 84856739604 scopus 로고    scopus 로고
    • Ipilimumab in pretreated patients with metastatic uveal melanoma: Safety and clinical efficacy
    • Danielli R, Ridolfi R, Chiarion-Sileni V, et al. Ipilimumab in pretreated patients with metastatic uveal melanoma: safety and clinical efficacy. Cancer Immunol Immunother 2012; 61: 41-8.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 41-48
    • Danielli, R.1    Ridolfi, R.2    Chiarion-Sileni, V.3
  • 22
    • 34548257760 scopus 로고    scopus 로고
    • Review: Anti-CTLA-4 antibody ipilimumab: Case studies of clinical response and immune-related adverse events
    • Weber J. Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events. Oncologist 2007; 12: 864-72.
    • (2007) Oncologist , vol.12 , pp. 864-872
    • Weber, J.1
  • 23
    • 78449244037 scopus 로고    scopus 로고
    • The emerging toxicity profiles of anti-CTLA-4 antibodies across clinical indications
    • Di Giacomo AM, Biagoli M, Maio M. The emerging toxicity profiles of anti-CTLA-4 antibodies across clinical indications. Semin Oncol 2010; 37: 499-507.
    • (2010) Semin Oncol , vol.37 , pp. 499-507
    • Di Giacomo, A.M.1    Biagoli, M.2    Maio, M.3
  • 24
    • 84874667943 scopus 로고    scopus 로고
    • Analysis of the onset and resolution of immune-related adverse events during treatment with ipilimumab in patients with metastatic melanoma
    • Lebbe C, O'Day S, Chiarion-Sileni V, et al. Analysis of the onset and resolution of immune-related adverse events during treatment with ipilimumab in patients with metastatic melanoma. Perspectives in Melanoma XII 2008; abstr. O-015.
    • (2008) Perspectives in Melanoma XII
    • Lebbe, C.1    O'Day, S.2    Chiarion-Sileni, V.3
  • 25
    • 24944459890 scopus 로고    scopus 로고
    • Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anticytotoxic T-lymphocyte Antigen-4
    • Attia P, Phan GQ, Maker AV, et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anticytotoxic T-lymphocyte Antigen-4. J Clin Oncol 2005; 23: 6043-53.
    • (2005) J Clin Oncol , vol.23 , pp. 6043-6053
    • Attia, P.1    Phan, G.Q.2    Maker, A.V.3
  • 26
    • 77953475151 scopus 로고    scopus 로고
    • Association between immunerelated adverse events (irAEs) and disease control or overall survival in patients (pts) with advanced melanoma treated with 10 mg/kg ipilimumab in three phase II clinical trials
    • Lutzky J, Wolchok J, Hamid O, et al. Association between immunerelated adverse events (irAEs) and disease control or overall survival in patients (pts) with advanced melanoma treated with 10 mg/kg ipilimumab in three phase II clinical trials. J Clin Oncol 2009; 27: 15s, (suppl; abstr 9034).
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL. , pp. 9034
    • Lutzky, J.1    Wolchok, J.2    Hamid, O.3
  • 27
    • 79953784382 scopus 로고    scopus 로고
    • Ipilimumab experience in heavily pretreated patients with melanoma in an expanded access program at the University Hospital of Siena (Italy)
    • Di Giacomo AM, Danielli R, Calabr L, et al. Ipilimumab experience in heavily pretreated patients with melanoma in an expanded access program at the University Hospital of Siena (Italy). Cancer Immunol Immunother 2011; 60: 467-77.
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 467-477
    • Di Giacomo, A.M.1    Danielli, R.2    Calabr, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.