Characteristics and outcomes of patients with vasoplegic versus tissue dysoxic septic shock

Shock

Volumn 40, Issue 1, 2013, Pages 11-14

  Sterling, Sarah A ^a   Puskarich, Michael A ^a   Shapiro, Nathan I ^b   Trzeciak, Stephen ^c   Kline, Jeffrey A ^d   Summers, Richard L ^a   Jones, Alan E ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b Department of Pathology   (United States)

^c Division of Female Pelvic Medicine and Reconstructive Surgery   (United States)

^d INDIANA UNIVERSITY   (United States)

Author keywords

Hyperlactatemia; Lactate; Mortality; Sepsis; Septic shock

Indexed keywords

LACTIC ACID;

ADULT; AGED; ARTICLE; CLINICAL ASSESSMENT; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; OXYGEN SATURATION; PREDICTOR VARIABLE; RANDOMIZED CONTROLLED TRIAL; SEPTIC SHOCK; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; SYSTOLIC BLOOD PRESSURE; TISSUE DYSOXIC SEPTIC SHOCK; VASOPLEGIC SEPTIC SHOCK;

AGED; BLOOD PRESSURE; FEMALE; HOSPITAL MORTALITY; HUMANS; HYPOTENSION; MALE; MIDDLE AGED; SHOCK, SEPTIC;

EID: 84880068668     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318298836d     Document Type: Article

References (11)

1. Angus D, Linde-Zwirble W, Lidicker J, Clermont G, Carcillo J, Pinsky M: Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29:1303-1310, 2001.
2. Wang HE, Shapiro NI, Angus DC, Yealy DM: National estimates of severe sepsis in United States emergency departments. Crit Care Med 35:1928-1936, 2007.
3. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G, et al.: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 31:1250-1256, 2003.
4. Mikkelsen M, Miltiades A, Gaieski D, Goyal M, Fuchs BD, Shah CV, Bellamy SL, Christie JD: Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock. Crit Care Med 37:1670-1677, 2009.
5. Song H, Shin TG, Kang MJ, Sim MS, Jo IJ, Song KJ, Jeong YK: Predicting factors associated with clinical deterioration in sepsis patients with intermediate levels of serum lactate. Shock 38:249-255, 2012.
6. Jones AE, Shapiro NI, Trzeciak S, Arnold RC, Claremont HA, Kline JA; Emergency Medicine Shock Research Network (EMShockNet) Investigators: Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA 303:739-746, 2010.
7. Puskarich MA, Trzeciak S, Shapiro NI, Heffner AC, Kline JA, Jones AE; Emergency Medicine Shock Research Network (EMSHOCKNET) Outcomes of patients undergoing early sepsis resuscitation for cryptic shock compared with overt shock. Resuscitation 82:1289-1293, 2011.
8. Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR: A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol 49:1373-1379, 1996.
9. Hernandez G, Castro R, Romero C: Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock? J Crit Care 26:435, 2011.
10. Hernandez G, Bruhn A, Castro R: Persistent sepsis-induced hypotension without hyperlactatemia: a distinct clinical and physiological profile within the spectrum of septic shock. Crit Care Res Pract 2012:536852, 2012.
11. Pope JV, Jones AE, Gaieski DF, Arnold RC, Trzeciak S, Shapiro NI; Emergency Medicine Shock Research Network (EMShockNet) Investigators: Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis. Shock 32:35-39, 2009.