Involvement of carboxylesterase in hydrolysis of propranolol prodrug during permeation across rat skin

Pharmaceutics

Volumn 5, Issue 3, 2013, Pages 371-384

  Imai, Teruko ^a   Takase, Yuko ^a   Iwase, Harunobu ^a   Hashimoto, Mitsuru ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Carboxylesterase; Hydrolysis; Prodrug; Skin permeation

Indexed keywords

CAPROYL PROPRANOLOL; CARBOXYLESTERASE; ESTERASE; HYDROLASE; HYDROLASE A; HYDROLASE C; PROPRANOLOL; RL2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG PENETRATION; DRUG TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; LIVER MICROSOME; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; SKIN PENETRATION; SKINFOLD THICKNESS;

EID: 84880057317     PISSN: None     EISSN: 19994923     Source Type: Journal    
DOI: 10.3390/pharmaceutics5030371     Document Type: Article

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