Antimutagenic and antioxidant properties of plumbagin and other naphthoquinones

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 755, Issue 1, 2013, Pages 30-41

  Kumar, Sanjeev ^a   Gautam, Satyendra ^a   Sharma, Arun ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Antimutagenicity; Antioxidant; Knockouts; Microarray; Naphthoquinones

Indexed keywords

AMPICILLIN; ASCORBIC ACID; CRYSTAL VIOLET; JUGLONE; MANNITOL; MENADIONE; PLASMID DNA; PLUMBAGIN; QUERCETIN; RIFAMPICIN; RNA POLYMERASE;

AMES TEST; ANTIBIOTIC RESISTANCE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ESCHERICHIA COLI; GAMMA RADIATION; GENE; GENE EXPRESSION; GENE FUNCTION; HYCB GENE; LIGA GENE; MICROARRAY ANALYSIS; MUTATION INHIBITION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REP GENE; SALMONELLA TYPHIMURIUM; SODC GENE; SPEE GENE; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING; UPREGULATION; XTHA GENE; YBAK GENE; YJFC GENE;

AMPLIFIED RNA; ANTIMUTAGENIC POTENTIAL; ANTIMUTAGENICITY; ANTIOXIDANT; AP; ARNA; CFU; COLONY-FORMING UNITS; HIS; HISTIDINE; JU; JUGLONE; KNOCKOUTS; ME; MENADIONE; MICROARRAY; NAPHTHOQUINONES; PL; PLUMBAGIN; RIF(R); RIFAMPICIN RESISTANT; SPC; SPONTANEOUS REVERSION; SR; STANDARD PLATE COUNT; WILD TYPE.; WT;

ANTICOAGULANTS; ANTIFIBRINOLYTIC AGENTS; ANTIMUTAGENIC AGENTS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; MOLECULAR STRUCTURE; NAPHTHOQUINONES; NUCLEIC ACID SYNTHESIS INHIBITORS; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RIFAMPIN; SALMONELLA TYPHIMURIUM; STRUCTURE-ACTIVITY RELATIONSHIP; VITAMIN K 3;

ESCHERICHIA COLI; LIGA;

EID: 84880039380     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.05.007     Document Type: Article

References (38)

1. Babula P., Adam V., Havel L., Kizek R. Noteworthy secondary metabolites naphthoquinones-their occurrence, pharmacological properties and analysis. Curr. Pharm. Anal. 2009, 5:47-68.
2. Mallavadhani U.V., Sahu G., Muralidhar J. Screening of Plumbago species for the bio-active marker plumbagin. Pharm. Biol. 2002, 40:508-511.
3. Likhitwitayawuid K., Kaewamatawong R., Ruangrungsi N., Krungkrai J. Antimalarial naphthoquinones from Nepenthes thorelii. Planta Med. 1998, 64:237-241.
4. Sugie S., Okamoto K., Rahman K.M.W., Tanaka T., Kawai K., Yamahara J., Mori H. Inhibitory effect of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats. Cancer Lett. 1998, 127:177-183.
5. Itoigawa M., Takeya K., Furukawa H. Cardiotonic action of plumbagin on guinea-pig papillary muscle. Planta Med. 1991, 57:317-319.
6. Topal S., Kocacaliskan I., Arslan O., Tel A.Z. Herbicidal effects of juglone as an allelochemical. Phyton 2007, 46:259-269.
7. Maron D.M., Ames B.N. Revised methods of the Salmonella mutagenicity test. Mutat. Res. 1983, 113:173-215.
8. Garibyan L., Huang T., Kim M., Wolff E., Nguyen A., Nguyen T., Diep A., Hu K., Iverson A., Yang H., Miller J.H. Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome. DNA Repair 2003, 2:593-608.
9. Sundaram S.G., Vijayalakshmi M., Nema R.K. Antimutagenicity of ethanol extract of Derris brevipes. J. Chem. Pharm. Res. 2010, 2:598-603.
10. Saxena S., Gautam S., Maru G., Kawle D., Sharma A. Suppression of error prone pathway is responsible for antimutagenic activity of honey. Food Chem. Toxicol. 2012, 50:625-633.
11. Ong T., Wong W.Z., Stewart J.D., Brockman H.E. Chlorophyllin: a potent antimutagen against environmental and dietary complex mixture. Mutat. Res. 1986, 173:111-115.
12. Kumar S., Gautam S., Sharma A. Identification of antimutagenic properties of anthocyanins, other polyphenols from rose (Rosa centifolia) petals and tea. J. Food Sci. 2013, 10.1111/1750-3841.12135.
13. Kumar S., Gautam S., Powar S., Sharma A. Microbial decontamination of medicinally important herbals using gamma radiation and their biochemical characterization. Food Chem. 2010, 119:328-335.
14. Kunchandy E., Rao M.N.A. Oxygen radical scavenging activity of curcumin. Int. J. Pharm. 1990, 58:237-240.
15. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual 1989, Cold Spring Harvor Press, New York.
16. Weel-Sneve R., Bjoras M., Kristiansen K.I. Overexpression of the LexA-regulated tisAB RNA in E. coli inhibits SOS functions; implications for regulation of the SOS response. Nucleic Acids Res. 2008, 36:6249-6259.
17. Gottesman S., Halpern E., Trisler P. Role of sulA and sulB in filamentation by Lon mutants of Escherichia coli K-12. J. Bacteriol. 1981, 148:265-273.
18. Lane H.E., Denhardt D.T. The rep mutation. IV. Slower movement of replication forks in Escherichia coli rep strains. J. Mol. Biol. 1975, 97:99-112.
19. Pro by Haemophilus influenzae YbaK protein. J. Biol. Chem. 2004, 279:42359-42362.
20. Stevens L. The biochemical role of naturally occurring polyamines in nucleic acid synthesis. Biol. Rev. 1970, 45:1-25.
21. Battistoni A., Pacello F., Folcarelli S., Ajello M., Donnarumma G., Greco R., Ammendolia M.G., Touati D., Rotilio G., Valenti P. Increased expression of periplasmic Cu, Zn superoxide dismutase enhances survival of Escherichia coli invasive strains within nonphagocytic cells. Infect. Immun. 2000, 68:30-37.
22. Loewen P.C., Hu B., Strutinsky J., Sparling R. Regulation in the rpoS regulon of Escherichia coli. Can. J. Microbiol. 1998, 44:707-717.
23. Sauter M., Bohm R., Bock A. Mutational analysis of the operon (hyc) determining hydrogenase 3 formation in Escherichia coli. Mol. Microbiol. 1992, 6:1523-1532.
24. Lehman I.R. DNA ligase: structure, mechanism, and function. Science 1974, 186:790-797.
25. de Paiva S.R., Figueiredo M.R., Aragão T.V., Kaplan M.A.C. Antimicrobial activity in vitro of plumbagin isolated from Plumbago species. Mem. Inst. Oswaldo Cruz 2003, 98:959-961.
26. Chen J.W., Sun C.M., Sheng W.L., Wang Y.C., Syu W.J. Expression analysis of up-regulated genes responding to plumbagin in Escherichia coli. J. Bacteriol. 2006, 188:456-463.
27. Inbaraj J.J., Chignell C.F. Cytotoxic action of juglone and plumbagin: a mechanistic study using HaCaT keratinocytes. Chem. Res. Toxicol. 2004, 17:55-62.
28. Ollinger K., Brunm A. Effect of hydroxyl substituent position on 1,4-naphthoquinone toxicity to rat hepatocyte. J. Biol. Chem. 1991, 266:21496-21503.
29. Edenharder R., Tang X. Inhibition of the mutagenicity of 2-nitrofluorene, 3-nitrofluoranthene and 1-nitropyrene by flavonoids, coumarins, quinones and other phenolic compounds. Food Chem. Toxicol. 1997, 35:357-372.
30. Sandur S.K., Ichikawa H., Sethi G., Ahn K.S., Aggarwal B.B. Plumbagin (5-hydroxyl-2-methyl-1, 4-naphthoquinone) suppresses NF-kB activation and NF-kB-regulated gene products through modulation of p65 and IkBa kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents. J. Biol. Chem. 2006, 281:17023-17033.
31. Bouck N., Kokkinakis D., Ostrowsky J. Induction of a step in carcinogenesis that is normally associated with mutagenesis by nonmutagenic concentrations of 5-azacytidine. Membr. Cell Biol. 1984, 4:1231-1237.
32. Tilak J.C., Devasagayam T.P., Banerjee M., Adhikari S., Chintalwar G.J., Chattopadhyay S. Differential antioxidant effects of plumbagin in rat tissues. BARC Newslett. (Founder's Day Special Issue) 2002, 117-129.
33. Pillai S.P., Shankel D.M. Polyamines and their potential to be antimutagens. Mutat. Res. 1997, 377:217-224.
34. Balasundaram D., Dinman J.D., Wickner R.B., Tabor C.W., Tabor H. Spermidine deficiency increases +1 ribosomal frameshifting efficiency and inhibits Ty1 retrotransposition in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 1994, 91:172-176.
35. Bacher J.M., Schimmel P. An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS response. Proc. Natl. Acad. Sci. USA 2007, 104:1907-1912.
36. Humayun M.Z. SOS and Mayday: multiple inducible mutagenic pathways in Escherichia coli. Mol. Microbiol. 1998, 30:905-910.
37. Nunez C., Esteve-Nunez A., Giometti C., Tollaksen S., Khare T., Lin W., Lovley D.R., Methé B.A. DNA microarray and proteomic analyses of the RpoS regulon in Geobacter sulfurreducens. J. Bacteriol. 2006, 188:2792-2800.
38. Yan G., Hua Z., Du G., Chen J. Adaptive response of Bacillus sp. F26 to hydrogen peroxide and menadione. Curr. Microbiol. 2006, 52:238-242.