Returning to overuse activity following a supraspinatus and infraspinatus tear leads to joint damage in a rat model

Journal of Biomechanics

Volumn 46, Issue 11, 2013, Pages 1818-1824

  Reuther, Katherine E ^a   Thomas, Stephen J ^a   Evans, Elisabeth F ^a   Tucker, Jennica J ^a   Sarver, Joseph J ^a   Ilkhani Pour, Sarah ^a   Gray, Chancellor F ^a   Voleti, Pramod B ^a   Glaser, David L ^a   Soslowsky, Louis J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Animal model; Chondrogenic phenotype; Overuse injury; Rotator cuff

Indexed keywords

AMBULATORY MEASUREMENT; ANIMAL MODEL; BIOLOGICAL MECHANISMS; BIOLOGICAL PROPERTIES; CHONDROGENIC PHENOTYPES; OVERUSE INJURY; ROTATOR CUFF; TRANSCRIPTIONAL REGULATION;

CARTILAGE; JOINTS (ANATOMY);

TENDONS;

AGGRECANASE 1; AGGRECANASE 2; COLLAGENASE 3; INTERLEUKIN 1BETA; STROMELYSIN; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN A;

ACAN GENE; ADAMTS4 GENE; ADAMTS5 GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CARTILAGE; CARTILAGE CELL; CASP3 GENE; CELL DENSITY; CELL SHAPE; COL2A1 GENE; CONTROLLED STUDY; GAPDH GENE; GENE; GENE EXPRESSION REGULATION; GLENOID CARTILAGE; HISTOPATHOLOGY; IL1B GENE; INFRASPINATUS MUSCLE; JOINT FUNCTION; JOINT INJURY; MMP13 GENE; MMP3 GENE; MOBILIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; ROTATOR CUFF INJURY; RUNX2 GENE; SHOULDER; SOX9 GENE; SUPRASPINATUS MUSCLE; TNFA GENE; TRANSCRIPTION REGULATION; VEGFA GENE;

ANIMAL MODEL; CHONDROGENIC PHENOTYPE; OVERUSE INJURY; ROTATOR CUFF;

ANIMALS; BIOMECHANICAL PHENOMENA; CARTILAGE, ARTICULAR; CHONDROGENESIS; CUMULATIVE TRAUMA DISORDERS; DISEASE MODELS, ANIMAL; ELASTIC MODULUS; GENE EXPRESSION; HUMANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; ROTATOR CUFF; SHOULDER JOINT; TENDONS;

EID: 84880035131     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2013.05.007     Document Type: Article

References (32)

1. Archambault J.M., Jelinsky S.A., Lake S.P., Hill A.A., Glaser D.L., Soslowsky L.J. Rat supraspinatus tendon expresses cartilage markers with overuse. Journal of Orthopaedic Research 2007, 25:617-624.
2. Attia M., Huet E., Gossard C., Menashi S., Tassoni M.C., Martelly I. Early events of overused supraspinatus tendons involve matrix metalloproteinases and EMMPRIN/CD147 in the absence of inflammation. American Journal of Sports Medicine 2013, 41:908-917.
3. Attia M., Scott A., Duchesnay A., Carpentier G., Soslowsky L.J., Huynh M.B., Van Kuppevelt T.H., Gossard C., Courty J., Tassoni M.C., Martelly I. Alterations of overused supraspinatus tendon: a possible role of glycosaminoglycans and HARP/pleiotrophin in early tendon pathology. Journal of Orthopaedic Research 2012, 30:61-71.
4. Burkhart S.S. Arthroscopic treatment of massive rotator cuff tears. Clinical results and biomechanical rationale. Clinical Orthopaedics and Related Research 1991, 267:45-56.
5. Hayes W.C., Keer L.M., Herrmann G., Mockros L.F. A mathematical analysis for indentation tests of articular cartilage. Journal of Biomechanics 1972, 5:541-551.
6. Herzog W., Diet S., Suter E., Mayzus P., Leonard T.R., Muller C., Wu J.Z., Epstein M. Material and functional properties of articular cartilage and patellofemoral contact mechanics in an experimental model of osteoarthritis. Journal of Biomechanics 1998, 31:1137-1145.
7. Hsu H.C., Luo Z.P., Stone J.J., Huang T.H., An K.N. Correlation between rotator cuff tear and glenohumeral degeneration. Acta Orthopaedica Scandinavica 2003, 74:89-94.
8. Hsu J.E., Reuther K.E., Sarver J.J., Lee C.S., Thomas S.J., Glaser D.L., Soslowsky L.J. Restoration of anterior-posterior rotator cuff force balance improves shoulder function in a rat model of chronic massive tears. Journal of Orthopaedic Research 2011, 29:1028-1033.
9. Keener J.D., Wei A.S., Kim H.M., Steger-May K., Yamaguchi K. Proximal humeral migration in shoulders with symptomatic and asymptomatic rotator cuff tears. Journal of Bone and Joint Surgery-American Volume 2009, 91:1405-1413.
10. Kleemann R.U., Krocker D., Cedraro A., Tuischer J., Duda G.N. Altered cartilage mechanics and histology in knee osteoarthritis: relation to clinical assessment (ICRS Grade). Osteoarthritis Cartilage 2005, 13:958-963.
11. Lakemeier S., Reichelt J.J., Timmesfeld N., Fuchs-Winkelmann S., Paletta J.R., Schofer M.D. The relevance of long head biceps degeneration in the presence of rotator cuff tears. BMC Musculoskeletal Disorders 2010, 11:191.
12. Lakemeier S., Schwuchow S.A., Peterlein C.D., Foelsch C., Fuchs-Winkelmann S., Archontidou-Aprin E., Paletta J.R., Schofer M.D. Expression of matrix metalloproteinases 1, 3, and 9 in degenerated long head biceps tendon in the presence of rotator cuff tears: an immunohistological study. BMC Musculoskeletal Disorders 2010, 11:271.
13. Nakajima D., Yamamoto A., Kobayashi T., Osawa T., Shitara H., Ichinose T., Takasawa E., Takagishi K. The effects of rotator cuff tears, including shoulders without pain, on activities of daily living in the general population. Journal of Orthopaedic Science 2012, 17:136-140.
14. Neer C.S. Impingement lesions. Clinical Orthopaedics and Related Research 1983, 173:70-77.
15. Neer C.S., Craig E.V., Fukuda H. Cuff-tear arthropathy. Journal of Bone and Joint Surgery-American Volume 1983, 65:1232-1244.
16. Oh J.H., Jun B.J., McGarry M.H., Lee T.Q. Does a critical rotator cuff tear stage exist?: a biomechanical study of rotator cuff tear progression in human cadaver shoulders. Journal of Bone and Joint Surgery-American Volume 2011, 93:2100-2109.
17. Peltz C.D., Perry S.M., Getz C.L., Soslowsky L.J. Mechanical properties of the long-head of the biceps tendon are altered in the presence of rotator cuff tears in a rat model. Journal of Orthopaedic Research 2009, 27:416-420.
18. Perry S.M., Getz C.L., Soslowsky L.J. After rotator cuff tears, the remaining (intact) tendons are mechanically altered. Journal of Shoulder and Elbow Surgery 2009, 18:52-57.
19. Perry S.M., Getz C.L., Soslowsky L.J. Alterations in function after rotator cuff tears in an animal model. Journal of Shoulder and Elbow Surgery 2009, 18:296-304.
20. Pfaffl M.W., Horgan G.W., Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Research 2002, 30:e36.
21. Reno C., Marchuk L., Sciore P., Frank C.B., Hart D.A. Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues. Biotechniques 1997, 22:1082-1086.
22. Reuther K.E., Sarver J.J., Schultz S.M., Lee C.S., Sehgal C.M., Glaser D.L., Soslowsky L.J. Glenoid cartilage mechanical properties decrease after rotator cuff tears in a rat model. Journal of Orthopaedic Research 2012, 30:1435-1439.
23. Reuther K.E., Thomas S.J., Sarver J.J., Tucker J.J., Lee C.S., Gray C.F., Glaser D.L., Soslowsky L.J. Effect of return to overuse activity following an isolated supraspinatus tendon tear on adjacent intact tendons and glenoid cartilage in a rat model. Journal of Orthopaedic Research 2013, 31:710-715.
24. Sarver J.J., Dishowitz M.I., Kim S.Y., Soslowsky L.J. Transient decreases in forelimb gait and ground reaction forces following rotator cuff injury and repair in a rat model. Journal of Biomechanics 2010, 43:778-782.
25. Setton L.A., Elliott D.M., Mow V.C. Altered mechanics of cartilage with osteoarthritis: human osteoarthritis and an experimental model of joint degeneration. Osteoarthritis Cartilage 1999, 7:2-14.
26. Soslowsky L.J., Carpenter J.E., DeBano C.M., Banerji I., Moalli M.R. Development and use of an animal model for investigations on rotator cuff disease. Journal of Shoulder and Elbow Surgery 1996, 5:383-392.
27. Soslowsky L.J., Thomopoulos S., Tun S., Flanagan C.L., Keefer C.C., Mastaw J., Carpenter J.E. Neer Award 1999. Overuse activity injures the supraspinatus tendon in an animal model: a histologic and biomechanical study. Journal of Shoulder and Elbow Surgery 2000, 9:79-84.
28. Thomas S.J., Miller K.S., Soslowsky L.J. The upper band of the subscapularis tendon in the rat has altered mechanical and histologic properties. Journal of Shoulder and Elbow Surgery 2012, 21:23-31.
29. Thomopoulos S., Das R., Birman V., Smith L., Ku K., Elson E.L., Pryse K.M., Marquez J.P., Genin G.M. Fibrocartilage tissue engineering: the role of the stress environment on cell morphology and matrix expression. Tissue Engineering Part A 2011, 17:1039-1053.
30. Thomopoulos S., Williams G.R., Soslowsky L.J. Tendon to bone healing: differences in biomechanical, structural, and compositional properties due to a range of activity levels. Journal of Biomechanical Engineering 2003, 125:106-113.
31. Wren T.A., Beaupre G.S., Carter D.R. Mechanobiology of tendon adaptation to compressive loading through fibrocartilaginous metaplasia. Journal of Rehabilitation Research & Development 2000, 37:135-143.
32. Xu Y., Murrell G.A. The basic science of tendinopathy. Clinical Orthopaedics and Related Research 2008, 466:1528-1538.