Lithium treatment increases endothelial cell survival and autophagy in a mouse model of Fuchs endothelial corneal dystrophy

British Journal of Ophthalmology

Volumn 97, Issue 8, 2013, Pages 1068-1073

  Kim, Eun Chul ^a,b   Meng, Huan ^a   Jun, Albert S ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 12; LITHIUM CARBONATE; PROTEIN P62; THAPSIGARGIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARR BETA2 GENE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DENSITY; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONFOCAL MICROSCOPY; CONGENITAL CORNEA DYSTROPHY; CONTROLLED STUDY; DRUG EFFICACY; ENDOTHELIUM CELL; GENE; GENE SEQUENCE; GENETIC REGULATION; GSK3 BETA GENE; LMPA1 GEBE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; P62 GENE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; STRESS; TM9SF1 GENE; TMEM166 GENE; TMEM74 GENE; TRANSMISSION ELECTRON MICROSCOPY;

CORNEA; DRUGS;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CATTLE; CELL COUNT; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIUM, CORNEAL; FUCHS' ENDOTHELIAL DYSTROPHY; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HYDROGEN PEROXIDE; LITHIUM CARBONATE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; THAPSIGARGIN; TRANSCRIPTION FACTOR CHOP;

EID: 84880019018     PISSN: 00071161     EISSN: 14682079     Source Type: Journal    
DOI: 10.1136/bjophthalmol-2012-302881     Document Type: Article

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