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Volumn 38, Issue 4, 2013, Pages 333-336

Severe acute nephrotoxicity in a kidney transplant patient despite low tacrolimus levels: A possible interaction between donor and recipient genetic polymorphisms

Author keywords

calcineurin inhibitor nephrotoxicity; genetic polymorphism; renal transplant; tacrolimus

Indexed keywords

BASILIXIMAB; EVEROLIMUS; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

EID: 84879992639     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/jcpt.12066     Document Type: Article
Times cited : (9)

References (30)
  • 1
    • 38449094179 scopus 로고    scopus 로고
    • Metabolism of Tacrolimus (FK506) and recent topics in clinical pharmacokinetics
    • Iwasaki K,. Metabolism of Tacrolimus (FK506) and recent topics in clinical pharmacokinetics. Drug Metab Pharmacokinet, 2007; 22: 328-335.
    • (2007) Drug Metab Pharmacokinet , vol.22 , pp. 328-335
    • Iwasaki, K.1
  • 2
    • 0029849460 scopus 로고    scopus 로고
    • Relationship of FK506 whole blood concentrations and efficacy and toxicity after liver and kidney transplantation
    • Kershner RP, Fitzsimmons WE,. Relationship of FK506 whole blood concentrations and efficacy and toxicity after liver and kidney transplantation. Transplantation, 1996; 62: 920-926.
    • (1996) Transplantation , vol.62 , pp. 920-926
    • Kershner, R.P.1    Fitzsimmons, W.E.2
  • 3
    • 0242351679 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between corticosteroids and tacrolimus after renal transplantation
    • Anglicheau D, Flamant M, Schlageter MH, et al,. Pharmacokinetic interaction between corticosteroids and tacrolimus after renal transplantation. Nephrol Dial Transplant, 2003; 18: 2409-2414.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 2409-2414
    • Anglicheau, D.1    Flamant, M.2    Schlageter, M.H.3
  • 5
    • 0030006845 scopus 로고    scopus 로고
    • Bimodal distribution of renal cytochrome P450 3A activity in humans
    • Haehner BD, Gorski JC, Vandenbranden M,. Bimodal distribution of renal cytochrome P450 3A activity in humans. Mol Pharmacol, 1996; 50: 52.
    • (1996) Mol Pharmacol , vol.50 , pp. 52
    • Haehner, B.D.1    Gorski, J.C.2    Vandenbranden, M.3
  • 6
    • 84858427636 scopus 로고    scopus 로고
    • CYP3A5 genotype-phenotype analysis in the human kidney reveals a strong site-specific expression of CYP3A5 in the proximal tubule in carriers of the CYP3A5*1 allele
    • doi: 10.1124/dmd.111.042648. Epub 2012 Jan 3.
    • Bolbrinker J, Seeberg S, Schostak M, Kempkensteffen C, Baelde H, de Heer E, Kreutz R,. CYP3A5 genotype-phenotype analysis in the human kidney reveals a strong site-specific expression of CYP3A5 in the proximal tubule in carriers of the CYP3A5*1 allele. Drug Metab Dispos, 2012; 40: 639-641. doi: 10.1124/dmd.111.042648. Epub 2012 Jan 3.
    • (2012) Drug Metab Dispos , vol.40 , pp. 639-641
    • Bolbrinker, J.1    Seeberg, S.2    Schostak, M.3    Kempkensteffen, C.4    Baelde, H.5    De Heer, E.6    Kreutz, R.7
  • 7
    • 80055000500 scopus 로고    scopus 로고
    • Lower tacrolimus daily dose requirements and acute rejection rates in the CYP3A5 nonexpressers than expressers
    • Tang HL, Xie HG, Yao Y, Hu YF,. Lower tacrolimus daily dose requirements and acute rejection rates in the CYP3A5 nonexpressers than expressers. Pharmacogenet Genomics, 2011; 21: 713-720.
    • (2011) Pharmacogenet Genomics , vol.21 , pp. 713-720
    • Tang, H.L.1    Xie, H.G.2    Yao, Y.3    Hu, Y.F.4
  • 8
    • 34547830270 scopus 로고    scopus 로고
    • Cytochrome P450 3A5 expression in the kidneys of patients with calcineurin inhibitor nephrotoxicity
    • Joy MS, Hogan SL, Thompson BD,. Cytochrome P450 3A5 expression in the kidneys of patients with calcineurin inhibitor nephrotoxicity. Nephrol Dial Transplant, 2007; 22: 1963.
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 1963
    • Joy, M.S.1    Hogan, S.L.2    Thompson, B.D.3
  • 9
    • 79955642359 scopus 로고    scopus 로고
    • Expression of CYP3A5 and P-glycoprotein in renal allografts with histological signs of calcineurin inhibitor nephrotoxicity
    • Metalidis C, Lerut E, Naesens M, Kuypers DRJ,. Expression of CYP3A5 and P-glycoprotein in renal allografts with histological signs of calcineurin inhibitor nephrotoxicity. Transplantation, 2011; 91: 1098-1102.
    • (2011) Transplantation , vol.91 , pp. 1098-1102
    • Metalidis, C.1    Lerut, E.2    Naesens, M.3    Kuypers, D.R.J.4
  • 10
    • 0037478407 scopus 로고    scopus 로고
    • Human extrahepatic cytochromes P450: Function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts
    • Ding X, Kaminsky LS,. Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu Rev Pharmacol Toxicol, 2003; 43: 149-173.
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 149-173
    • Ding, X.1    Kaminsky, L.S.2
  • 11
    • 80054963743 scopus 로고    scopus 로고
    • Effect of a new functional CYP3A4 polymorphism on calcineurin inhibitors' dose requirements and trough blood levels in stable renal transplant patients
    • Elens L, van Schaik RH, Panin N, et al,. Effect of a new functional CYP3A4 polymorphism on calcineurin inhibitors' dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenomics, 2011; 12: 1383-1396.
    • (2011) Pharmacogenomics , vol.12 , pp. 1383-1396
    • Elens, L.1    Van Schaik, R.H.2    Panin, N.3
  • 12
    • 80054924410 scopus 로고    scopus 로고
    • A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients
    • Elens L, Bouamar R, Hesselink DA, et al,. A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients. Clin Chem, 2011; 57: 1574-1583.
    • (2011) Clin Chem , vol.57 , pp. 1574-1583
    • Elens, L.1    Bouamar, R.2    Hesselink, D.A.3
  • 13
    • 79960633918 scopus 로고    scopus 로고
    • Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs
    • Wang D, Guo Y, Wrighton SA, Cooke GE, Sadee W,. Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs. Pharmacogenomics J, 2011; 11: 274-286.
    • (2011) Pharmacogenomics J , vol.11 , pp. 274-286
    • Wang, D.1    Guo, Y.2    Wrighton, S.A.3    Cooke, G.E.4    Sadee, W.5
  • 14
    • 0033609168 scopus 로고    scopus 로고
    • Outcome of Kidney Transplantation from High-Risk Donors Is Determined by Both Structure and Function
    • Karpinski J, Lajoie G, Cattran D, et al,. Outcome of Kidney Transplantation From High-Risk Donors Is Determined By Both Structure and Function. Transplantation, 1999; 8: 1162-1167.
    • (1999) Transplantation , vol.8 , pp. 1162-1167
    • Karpinski, J.1    Lajoie, G.2    Cattran, D.3
  • 15
    • 0030027698 scopus 로고    scopus 로고
    • The use of therapeutic drug monitoring to optimize immunosuppressive therapy
    • Tsunoda SM, Aweeka FT,. The use of therapeutic drug monitoring to optimize immunosuppressive therapy. Clin Pharmacokinet, 1996; 30: 107-140.
    • (1996) Clin Pharmacokinet , vol.30 , pp. 107-140
    • Tsunoda, S.M.1    Aweeka, F.T.2
  • 16
    • 84864288733 scopus 로고    scopus 로고
    • The interactions of age, sex, body mass index, genetics, and steroid weight-based doses on tacrolimus dosing requirement after adult kidney transplantation
    • Stratta P, Quaglia M, Cena T, et al,. The interactions of age, sex, body mass index, genetics, and steroid weight-based doses on tacrolimus dosing requirement after adult kidney transplantation. Eur J Clin Pharmacol, 2012; 68: 671-680.
    • (2012) Eur J Clin Pharmacol , vol.68 , pp. 671-680
    • Stratta, P.1    Quaglia, M.2    Cena, T.3
  • 17
    • 78049365901 scopus 로고    scopus 로고
    • BK virus sequences in specimens from aborted fetuses
    • Boldorini R, Allegrini S, Miglio U, et al,. BK virus sequences in specimens from aborted fetuses. J Med Virol, 2010; 82: 2127-2132.
    • (2010) J Med Virol , vol.82 , pp. 2127-2132
    • Boldorini, R.1    Allegrini, S.2    Miglio, U.3
  • 18
    • 13444291244 scopus 로고    scopus 로고
    • CYP3A5*3 and CYP3A4*18 single nucleotide polymorphisms in a Chinese population
    • Hu YF, He J, Chen GL,. CYP3A5*3 and CYP3A4*18 single nucleotide polymorphisms in a Chinese population. Clin Chim Acta, 2005; 353: 87-92.
    • (2005) Clin Chim Acta , vol.353 , pp. 87-92
    • Hu, Y.F.1    He, J.2    Chen, G.L.3
  • 19
    • 34250326888 scopus 로고    scopus 로고
    • MDR1 gene polymorphisms and risk of recurrence in patients with hepatocellular carcinoma after liver transplantation
    • Wu L, Xu X, Shen J, et al,. MDR1 gene polymorphisms and risk of recurrence in patients with hepatocellular carcinoma after liver transplantation. J Surg Oncol, 2007; 96: 62-68.
    • (2007) J Surg Oncol , vol.96 , pp. 62-68
    • Wu, L.1    Xu, X.2    Shen, J.3
  • 20
    • 77955174312 scopus 로고    scopus 로고
    • Tacrolimus dose requirements and CYP3A5 genotype and the development of calcineurin inhibitor-associated nephrotoxicity in renal allograft recipients
    • Kuypers DR, Naesens M, de Jonge H, Lerut E, Verbeke K, Vanrenterghem Y,. Tacrolimus dose requirements and CYP3A5 genotype and the development of calcineurin inhibitor-associated nephrotoxicity in renal allograft recipients. Ther Drug Monit, 2010; 32: 394-404.
    • (2010) Ther Drug Monit , vol.32 , pp. 394-404
    • Kuypers, D.R.1    Naesens, M.2    De Jonge, H.3    Lerut, E.4    Verbeke, K.5    Vanrenterghem, Y.6
  • 21
    • 80053184901 scopus 로고    scopus 로고
    • CYP3A5 and ABCB1 polymorphisms in donor and recipient: Impact on Tacrolimus dose requirements and clinical outcome after renal transplantation
    • Glowacki F, Lionet A, Buob D, et al,. CYP3A5 and ABCB1 polymorphisms in donor and recipient: impact on Tacrolimus dose requirements and clinical outcome after renal transplantation. Nephrol Dial Transplant, 2011; 26: 3046-3050.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 3046-3050
    • Glowacki, F.1    Lionet, A.2    Buob, D.3
  • 22
    • 0028893714 scopus 로고
    • Further metabolism of FK 506 (Tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK 506
    • Iwasaki K, Shiraga T, Masuda H, et al,. Further metabolism of FK 506 (Tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK 506. Drug Metab Dispos, 1995; 23: 28-34.
    • (1995) Drug Metab Dispos , vol.23 , pp. 28-34
    • Iwasaki, K.1    Shiraga, T.2    Masuda, H.3
  • 23
    • 36148985704 scopus 로고    scopus 로고
    • CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine the long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients
    • Kuypers DR, de Jonge H, Naesens M, et al,. CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine the long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients. Clin Pharmacol Ther, 2007; 82: 711-725.
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 711-725
    • Kuypers, D.R.1    De Jonge, H.2    Naesens, M.3
  • 24
    • 0036851317 scopus 로고    scopus 로고
    • Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy
    • Shimada T, Terada A, Yokogawa K, et al,. Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy. Transplantation, 2002; 74: 1419-1424.
    • (2002) Transplantation , vol.74 , pp. 1419-1424
    • Shimada, T.1    Terada, A.2    Yokogawa, K.3
  • 25
    • 19444367600 scopus 로고    scopus 로고
    • Calcineurin inhibitor-induced nephrotoxicity and renal expression of P-glycoprotein
    • Joy MS, Nickeleit V, Hogan SL, Thompson BD, Finn WF,. Calcineurin inhibitor-induced nephrotoxicity and renal expression of P-glycoprotein. Pharmacotherapy, 2005; 25: 779-789.
    • (2005) Pharmacotherapy , vol.25 , pp. 779-789
    • Joy, M.S.1    Nickeleit, V.2    Hogan, S.L.3    Thompson, B.D.4    Finn, W.F.5
  • 26
    • 77249158801 scopus 로고    scopus 로고
    • Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part i
    • Staatz CE, Goodman LK, Tett SE,. Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I. Clin Pharmacokinet, 2010; 49: 141-175.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 141-175
    • Staatz, C.E.1    Goodman, L.K.2    Tett, S.E.3
  • 27
    • 21444449731 scopus 로고    scopus 로고
    • ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation
    • Hauser IA, Schaeffeler E, Gauer S, et al,. ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation. J Am Soc Nephrol, 2005; 16: 1501-1511.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1501-1511
    • Hauser, I.A.1    Schaeffeler, E.2    Gauer, S.3
  • 28
    • 0037183584 scopus 로고    scopus 로고
    • Neurotoxicity induced by tacrolimus after liver transplantation: Relation to genetic polymorphisms of the ABCB1 (MDR1) gene
    • Yamauchi A, Ieiri I, Kataoka Y, et al,. Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene. Transplantation, 2002; 74: 571-572.
    • (2002) Transplantation , vol.74 , pp. 571-572
    • Yamauchi, A.1    Ieiri, I.2    Kataoka, Y.3
  • 29
    • 11144358432 scopus 로고    scopus 로고
    • CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation
    • Anglicheau D, Thervet E, Etienne I, et al,. CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation. Clin Pharmacol Ther, 2004; 75: 422-433.
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 422-433
    • Anglicheau, D.1    Thervet, E.2    Etienne, I.3
  • 30
    • 84863813155 scopus 로고    scopus 로고
    • The effect of CYP3A5 6986A>G and ABCB1 3435C>T on tacrolimus dose-adjusted trough levels and acute rejection rates in renal transplant patients: A systematic review and meta-analysis
    • Terrazzino S, Quaglia M, Stratta P, Canonico PL, Genazzani AA,. The effect of CYP3A5 6986A>G and ABCB1 3435C>T on tacrolimus dose-adjusted trough levels and acute rejection rates in renal transplant patients: a systematic review and meta-analysis. Pharmacogenet Genomics, 2012; 22: 642-645.
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 642-645
    • Terrazzino, S.1    Quaglia, M.2    Stratta, P.3    Canonico, P.L.4    Genazzani, A.A.5


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