Lipid nanoparticles production by supercritical fluid assisted emulsion-diffusion

Journal of Supercritical Fluids

Volumn 82, Issue , 2013, Pages 34-40

  Campardelli, Roberta ^a   Cherain, Maxime ^b   Perfetti, Claire ^b   Iorio, Carlo ^b   Scognamiglio, Mariarosa ^a   Reverchon, Ernesto ^a   Della Porta, Giovanna ^a,b  

^a UNIVERSITY OF SALERNO   (Italy)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Continuous processing; Emulsion diffusion; Lipid nanoparticles; Supercritical fluid

Indexed keywords

AGGREGATION PHENOMENA; CONTINUOUS EXTRACTION; CONTINUOUS PROCESSING; CONVENTIONAL EMULSIONS; LIPID NANOPARTICLES; SUPERCRITICAL FLUID PROCESSING; SUPERCRITICAL PROCESSING; SUPERCRITICAL TECHNOLOGY;

DIFFUSION IN LIQUIDS; EFFLUENT TREATMENT; EMULSIFICATION; STEARIC ACID; SUPERCRITICAL FLUIDS;

NANOPARTICLES;

EID: 84879949310     PISSN: 08968446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.supflu.2013.05.020     Document Type: Article

References (27)

1. E. Blanco, C.W. Kessinger, B.D. Sumer, and J. Gao Multifunctional micellar nanomedicine for cancer therapy Experimental Biology and Medicine (Maywood, NJ) 234 2009 123 131
2. V.P. Torchilin Nanoparticulates As Drug Carriers 2006 Imperial College Press
3. R.H. Muller, K. Mader, and S. Gohla Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art European Journal of Pharmaceutics and Biopharmaceutics 50 2000 161 177 (Pubitemid 30326695)
4. A. zur Muhlen, C. Schwarz, and W. Mehnert Solid lipid nanoparticles (SLN) for controlled drug delivery - drug release and release mechanism European Journal of Pharmaceutics and Biopharmaceutics 45 1998 149 155 (Pubitemid 28167741)
5. F.-Q. Hu, S.-P. Jiang, Y.-Z. Du, H. Yuan, Y.-Q. Ye, and S. Zeng Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system Colloids and Surfaces B: Biointerfaces 45 2005 167 173 (Pubitemid 41415646)
6. R.H. Muller, S. Maassen, H. Weyhers, F. Specht, and J.S. Lucks Cytotoxicity of magnetite-loaded polylactide, polylactide/glycolide particles and solid lipid nanoparticles International Journal of Pharmaceutics 138 1996 85 94 (Pubitemid 26241925)
7. D.Z. Hou, C.S. Xie, K.J. Huang, and C.H. Zhu The production and characteristics of solid lipid nanoparticles (SLNs) Biomaterials 24 2003 1781 1785
8. V.R. Sinha, S. Srivastava, H. Goel, and V. Jindal Solid lipid nanoparticles (SLN'S) - trends and implications in drug targeting International Journal of Advances in Pharmaceutical Sciences 1 2011 212 238
9. V. Sanna, E. Gavini, M. Cossu, G. Rassu, and P. Giunchedi Solid lipid nanoparticles (SLN) as carriers for the topical delivery of econazole nitrate: in-vitro characterization, ex-vivo and in-vivo studies Journal of Pharmacy and Pharmacology 59 2007 1057 1064 (Pubitemid 47265352)
10. S.A. Wissing, O. Kayser, and R.H. Müller Solid lipid nanoparticles for parenteral drug delivery Advanced Drug Delivery Reviews 56 2004 1257 1272 (Pubitemid 38510473)
11. J. Weiss, E.A. Decker, D.J. McClements, K. Kristbergsson, T. Helgason, and T. Awad Solid lipid nanoparticles as delivery systems for bioactive food components Food Biophysics 3 2008 146 154
12. W. Mehnert, and K. Mader Solid lipid nanoparticles - production, characterization and applications Advanced Drug Delivery Reviews 47 2001 165 196 (Pubitemid 32324113)
13. H. Bunjes, K. Westesen, and M.H.J. Koch Crystallization tendency and polymorphic transitions in triglyceride nanoparticles International Journal of Pharmaceutics 129 1996 159 173 (Pubitemid 26098737)
14. E.B. Souto, and R.H. Muller Investigation of the factors influencing the incorporation of clotrimazole in SLN and NLC prepared by hot high-pressure homogenization Journal of Microencapsulation 23 2006 377 388 (Pubitemid 44132547)
15. V. Jenning, A. Lippacher, and S.H. Gohla Medium scale production of solid lipid nanoparticles (SLN) by high pressure homogenization Journal of Microencapsulation 19 2002 1 10 (Pubitemid 34083456)
16. B. Sjostrom, and B. Bergenstahl Preparation of submicron drug particles in lecithin-stabilized o/w emulsions.1. Model studies of the precipitation cholesteryl acetate International Journal of Pharmaceutics 88 1992 53 62 (Pubitemid 23000408)
17. B. Sjostrom, A. Kaplun, Y. Talmon, and B. Cabane Structures of nanoparticles prepared from oil-in-water emulsions Pharmaceutical Research 12 1995 39 48
18. M. Trotta, R. Cavalli, M.E. Carlotti, L. Battaglia, and F. Debernardi Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique International Journal of Pharmaceutics 288 2005 281 288 (Pubitemid 40038581)
19. M. Trotta, F. Debernardi, and O. Caputo Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique International Journal of Pharmaceutics 257 2003 153 160 (Pubitemid 36507041)
20. P. Chattopadhyay, B.Y. Shekunov, D. Yim, D. Cipolla, B. Boyd, and S. Farr Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system Advanced Drug Delivery Reviews 59 2007 444 453 (Pubitemid 47259225)
21. G. Della Porta, R. Campardelli, N. Falco, and E. Reverchon PLGA microdevices for retinoids sustained release produced by supercritical emulsion extraction: continuous versus batch operation layouts Journal of Pharmaceutical Sciences 100 2011 4357 4367
22. G. Della Porta, N. Falco, and E. Reverchon Continuous supercritical emulsions extraction: a new technology for biopolymer microparticles production Biotechnology and Bioengineering 108 2011 676 686
23. R. Campardelli, G. Della Porta, and E. Reverchon Solvent elimination from polymer nanoparticle suspensions by continuous supercritical extraction The Journal of Supercritical Fluids 70 2012 100 105
24. S. Liao, Y.C. Hou, S.Y. Li, X.T. Chen, and W.Z. Wu High-pressure phase equilibria for the binary system carbon dioxide plus benzyl alcohol Journal of Supercritical Fluids 55 2010 32 36
25. K. Brudi, N. Dahmen, and H. Schmieder Partition coefficients of organic substances in two-phase mixtures of water and carbon dioxide at pressures of 8 to 30 MPa and temperatures of 313 to 333 K The Journal of Supercritical Fluids 9 1996 146 151 (Pubitemid 126655323)
26. Y. Iwai, Y. Koga, H. Maruyama, and Y. Arai Solubilities of stearic acid, stearyl alcohol, and arachidyl alcohol in supercritical carbon dioxide at 35. degree. C Journal of Chemical & Engineering Data 38 1993 506 508
27. N. Falco, E. Reverchon, and G. Della Porta Continuous supercritical emulsions extraction: packed tower characterization and application to poly(lactic-co-glycolic acid) plus insulin microspheres production Industrial & Engineering Chemistry Research 51 2012 8616 8623