Definitive high-dose photon/proton radiotherapy for unresected mobile spine and sacral chordomas

Spine

Volumn 38, Issue 15, 2013, Pages

  Chen, Yen Lin ^a,c   Liebsch, Norbert ^a,c   Kobayashi, Wendy ^a   Goldberg, Saveli ^a,c   Kirsch, David ^b   Calkins, Geoffrey ^a   Childs, Stephanie ^a   Schwab, Joseph ^a,c   Hornicek, Francis ^a,c   Delaney, Thomas ^a,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Chordoma; nonoperation; radiotherapy

Indexed keywords

AGED; ARTICLE; BLADDER DYSFUNCTION; CANCER RADIOTHERAPY; CANCER SURVIVAL; CERVICAL SPINE; CHORDOMA; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CORE BIOPSY NEEDLE; DIARRHEA; DISEASE EXACERBATION; FECES INCONTINENCE; FEMALE; FOLLOW UP; GLUTEUS MAXIMUS MUSCLE; HEMATURIA; HUMAN; LUMBAR SPINE; MALE; METASTASIS FREE SURVIVAL; MOBILE SPINE; MUCOSA INFLAMMATION; NAUSEA AND VOMITING; NEUROLOGIC DISEASE; OVERALL SURVIVAL; PAIN; PARESTHESIA; PATIENT MOBILITY; PERINEAL NUMBNESS; PHOTON THERAPY; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTON THERAPY; RADIATION DERMATITIS; RADIATION DOSE; RECTUM HEMORRHAGE; RETROSPECTIVE STUDY; SACRAL INSUFFICIENCY FRACTURE; SACROCOCCYX CHORDOMA; SACRUM; SPINE FRACTURE; THORACIC SPINE; TREATMENT DURATION; TUMOR LOCALIZATION; TUMOR VOLUME; URINE INCONTINENCE;

AGED; CHORDOMA; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; FRACTURES, BONE; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES; SACRUM; SPINAL NEOPLASMS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84879939729     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e318296e7d7     Document Type: Article

References (29)

1. Sciubba DM, Chi JH, Rhines LD, et al. Chordoma of the spinal column. Neurosurg Clin N Am 2008; 19: 5-15.
2. Baratti D, Gronchi A, Pennacchioli E, et al. Chordoma: natural his-tory and results in 28 patients treated at a single institution. Ann Surg Oncol 2003; 10: 291-6.
3. Bergh P, Kindblom LG, Gunterberg B, et al. Prognostic factors in chordoma of the sacrum and mobile spine: a study of 39 patients. Cancer 2000; 88: 2122-34.
4. Boriani S, Bandiera S, Biagini R, et al. Chordoma of the mobile spine: fifty years of experience. Spine 2006; 31: 493-503.
5. Fuchs B. Operative management of sacral chordoma. J Bone Jt Surg 2005; 87: 2211-6.
6. Hanna SA, Aston WJS, Briggs TWR, et al. Sacral chordoma: can local recurrence after sacrectomy be predicted? Clin Orthop Relat Res 2008; 466: 2217-23.
7. Hulen CA, Temple HT, Fox WP, et al. Oncologic and functional outcome following sacrectomy for sacral chordoma. J Bone Joint Surg Am 2006; 88: 1532-9.
8. Ozaki T, Hillmann A, Winkelmann W. Surgical treatment of sacro-coccygeal chordoma. J Surg Oncol 1997; 64: 274-9.
9. Samson IR, Springfield DS, Suit HD, et al. Operative treatment of sacrococcygeal chordoma. a review of twenty-one cases. J Bone Jt Surg Am 1993; 75: 1476-84.
10. Schwab JH, Healey JH, Rose P, et al. The surgical management of sacral chordomas. Spine 2009; 34: 2700-4.
11. Yonemoto T, Tatezaki S, Takenouchi T, et al. The surgical manage-ment of sacrococcygeal chordoma. Cancer 1999; 85: 878-83.
12. York JE, Kaczaraj A, Abi-Said D, Fuller GN, et al. Sacral chor-doma: 40-year experience at a major cancer center. Neurosurgery 1999; 44: 74.
13. DeLaney TF, Liebsch NJ, Pedlow FX, et al. Phase II study of high-dose photon/proton radiotherapy in the management of spine sarcomas. Int J Radiat Oncol Biol Phys 2009; 74: 732-9.
14. Park L, DeLaney TF, Liebsch NJ, et al. Sacral chordomas: Impact of high-dose proton/photon-beam radiation therapy combined with or without surgery for primary versus recurrent tumor. Int J Radiat Oncol, Biol, Phys 2006; 65: 1514-21.
15. Gunterberg B, Kewenter J, Petersén I, et al. Anorectal function after major resections of the sacrum with bilateral or unilateral sacrifice of sacral nerves. Br J Surg 1976;63: 546-54.
16. Imai R, Kamada T, Tsuji H, et al. Carbon Ion Radiotherapy for Unresectable Sacral Chordomas. Clin Cancer Res 2004; 10: 5741-6.
17. Imai R, Kamada T, Tsuji H, et al. Effect of carbon ion radiotherapy for sacral chordoma: results of phase i-ii and phase ii clinical trials. Int J Radiat Oncol Biol Phys 2010; 77: 1470-6.
18. Henderson FC, McCool K, Seigle J, et al. Treatment of chordomas with cyberknife. Neurosurgery 2009; 64 (suppl 2): A44-53.
19. Terezakis SA, Lovelock DM, Bilsky MH, et al. Image-guided intensity-modulated photon radiotherapy using multifractionated regimen to paraspinal chordomas and rare sarcomas. Int J Radiat Oncol Biol Phys 2007; 69: 1502-8.
20. International Commission on Radiation Units and Measurements. Prescribing, recording, and reporting proton-beam therapy, ICRU Report, No. 78. J ICRU, No. 2, 2007 ISBN 9780199543489, Bethesda, MD: Oxford University Press, 2007.
21. Jawad MU, Scully SP. Surgery significantly improves survival in patients with chordoma. Spine 2010; 35: 117-23.
22. Devin C, Chong PY, Holt GE, et al. Level-adjusted perioperative risk of sacral amputations. J Surg Oncol 2006; 94: 203-11.
23. Kaiser TE, Pritchard DJ, Unni KK. Clinicopathologic study of sacrococcygeal chordoma. Cancer 1984; 53: 2574-8.
24. Catton C, O'Sullivan B, Bell R, et al. Chordoma: long-term follow-up after radical photon irradiation. Radiother Oncol 1996; 41: 67-72.
25. Fuller DB, Bloom JG. Radiotherapy for chordoma. Int J Radiat Oncol Biol Phys 1988; 15: 331-9.
26. Schoenthaler R, Castro JR, Petti PL, et al. Charged particle irra-diation of sacral chordomas. Int J Radiat Oncol Biol Phys 1993; 26: 291-8.
27. Rutz HP, Weber DC, Sugahara S, et al. Extracranial chordoma: out-come in patients treated with function-preserving surgery followed by spot-scanning proton beam irradiation. Int J Radiat Oncol Biol Phys 2007; 67: 512-20.
28. Wu AJ, Bilsky MH, Edgar MA, et al. Near-complete pathological response of chordoma to high-dose single-fraction radiotherapy. Neurosurgery 2009; 64: E389-90.
29. Pieters RS, Niemierko A, Fullerton BC, et al. Cauda equina toler-ance to high-dose fractionated irradiation. Int J Radiat Oncol Biol Phys 2006; 64: 251-7.