Extracranial chordoma: Outcome in patients treated with function-preserving surgery followed by spot-scanning proton beam irradiation

International Journal of Radiation Oncology Biology Physics

Volumn 67, Issue 2, 2007, Pages 512-520

  Rutz, Hans Peter ^a   Weber, Damien C ^a   Sugahara, Shinji ^b   Timmermann, Beate ^a   Lomax, Antony J ^a   Bolsi, Alessandra ^a   Pedroni, Eros ^a   Coray, Adolf ^a   Jermann, Martin ^a   Goitein, Gudrun ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

^b UNIVERSITY OF TSUKUBA HOSPITAL   (Japan)

Author keywords

Chordoma; Extracranial tumors; Proton beam therapy; Spot scanning

Indexed keywords

CELLS; PROTON IRRADIATION; RADIOTHERAPY; SURGERY; TUMORS;

CHORDOMA; EXTRACRANIAL TUMORS; PROTON BEAM THERAPY; SPOT SCANNING;

PATIENT TREATMENT;

ADOLESCENT; ADULT; AGED; ARTICLE; BONE NECROSIS; CANCER CONTROL; CANCER PATIENT; CANCER SURGERY; CERVICAL CHORDOMA; CHILD; CHORDOMA; CLINICAL ARTICLE; COBALT GRAY EQUIVALENT; COMMON TERMINOLOGY CRITERIA FOR ADVERSE EVENTS GRADING SYSTEM; EVALUATION; FATIGUE; FEMALE; FOLLOW UP; FUNCTION PRESERVING SURGERY; GANTRY RADIATION THERAPY; HUMAN; IMPLANT; INTENSITY MODULATED RADIATION THERAPY; LUMBAR CHORDOMA; MALE; METASTASIS; MUCOSAL DISEASE; NECROSIS; OVERALL SURVIVAL; PHOTON THERAPY; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROTON THERAPY; RADIATION DOSE; RATING SCALE; SACROCOCCYX CHORDOMA; SENSORY NEUROPATHY; SKIN FIBROSIS; SKIN MANIFESTATION; SPOT SCANNING RADIATION THERAPY; SUBCUTANEOUS NECROSIS; SUICIDE; SURGICAL TECHNIQUE; SURVIVAL RATE; THORACIC CHORDOMA; TISSUE NECROSIS; TREATMENT OUTCOME; UNIVARIATE ANALYSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CHORDOMA; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM, RESIDUAL; RADIOTHERAPY; RADIOTHERAPY DOSAGE; SPINAL NEOPLASMS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 33846257230     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.08.052     Document Type: Article

References (42)

1. Burger P.C., Makek M., and Kleihues P. Tissue polypeptide antigen staining of the chordoma and notochordal remnants. Acta Neuropathol (Berl) 70 (1986) 269-272
2. Salisbury J.R. The pathology of the human notochord. J Pathol 171 (1993) 253-255
3. McMaster M.L., Goldstein A.M., Bromley C.M., et al. Chordoma: Incidence and survival patterns in the United States, 1973-1995. Cancer Causes Control 12 (2001) 1-11
4. Soo M.Y. Chordoma: Review of clinicoradiological features and factors affecting survival. Australas Radiol 45 (2001) 427-434
5. Cummings B.J., Hodson D.I., and Bush R.S. Chordoma: The results of megavoltage radiation therapy. Int J Radiat Oncol Biol Phys 9 (1983) 633-642
6. Fuller D.B., and Bloom J.G. Radiotherapy for chordoma. Int J Radiat Oncol Biol Phys 15 (1988) 331-339
7. Romero J., Cardenes H., la Torre A., et al. Chordoma: Results of radiation therapy in eighteen patients. Radiother Oncol 29 (1993) 27-32
8. Catton C., O'Sullivan B., Bell R., et al. Chordoma: Long-term follow-up after radical photon irradiation. Radiother Oncol 41 (1996) 67-72
9. Zorlu F., Gurkaynak M., Yildiz F., et al. Conventional external radiotherapy in the management of clivus chordomas with overt residual disease. Neurol Sci 21 (2000) 203-207
10. Chandawarkar R.Y. Sacrococcygeal chordoma: Review of 50 consecutive patients. World J Surg 20 (1996) 717-719
11. Boriani S., Bandiera S., Biagini R., et al. Chordoma of the mobile spine: Fifty years of experience. Spine 31 (2006) 493-503
12. Pearlman A.W., and Friedman M. Radical radiation therapy of chordoma. Am J Roentgenol Radium Ther Nucl Med 108 (1970) 332-341
13. Debus J., Schulz-Ertner D., Schad L., et al. Stereotactic fractionated radiotherapy for chordomas and chondrosarcomas of the skull base. Int J Radiat Oncol Biol Phys 47 (2000) 591-596
14. Austin-Seymour M., Munzenrider J.E., Goitein M., et al. Progress in low-LET heavy particle therapy: Intracranial and paracranial tumors and uveal melanomas. Radiat Res Suppl 8 (1985) S219-S226
15. Austin-Seymour M., Munzenrider J., Goitein M., et al. Fractionated proton radiation therapy of chordoma and low-grade chondrosarcoma of the base of the skull. J Neurosurg 70 (1989) 13-17
16. Austin-Seymour M., Munzenrider J., Linggood R., et al. Fractionated proton radiation therapy of cranial and intracranial tumors. Am J Clin Oncol 13 (1990) 327-330
17. Castro J.R., Linstadt D.E., Bahary J.P., et al. Experience in charged particle irradiation of tumors of the skull base: 1977-1992. Int J Radiat Oncol Biol Phys 29 (1994) 647-655
18. Terahara A., Niemierko A., Goitein M., et al. Analysis of the relationship between tumor dose inhomogeneity and local control in patients with skull base chordoma. Int J Radiat Oncol Biol Phys 45 (1999) 351-358
19. Hug E.B., Loredo L.N., Slater J.D., et al. Proton radiation therapy for chordomas and chondrosarcomas of the skull base. J Neurosurg 91 (1999) 432-439
20. Noel G., Habrand J.L., Jauffret E., et al. Radiation therapy for chordoma and chondrosarcoma of the skull base and the cervical spine: Prognostic factors and patterns of failure. Strahlenther Onkol 179 (2003) 241-248
21. Schulz-Ertner D., Nikoghosyan A., Thilmann C., et al. Carbon ion radiotherapy for chordomas and low-grade chondrosarcomas of the skull base: Results in 67 patients. Strahlenther Onkol 179 (2003) 598-605
22. Igaki H., Tokuuye K., Okumura T., et al. Clinical results of proton beam therapy for skull base chordoma. Int J Radiat Oncol Biol Phys 60 (2004) 1120-1126
23. Weber D.C., Rutz H.P., Pedroni E.S., et al. Results of spot-scanning proton radiation therapy for chordoma and chondrosarcoma of the skull base: The Paul Scherrer Institut experience. Int J Radiat Oncol Biol Phys 63 (2005) 401-409
24. Schoenthaler R., Castro J.R., Petti P.L., et al. Charged particle irradiation of sacral chordomas. Int J Radiat Oncol Biol Phys 26 (1993) 291-298
25. Pedroni E., Bacher R., Blattmann H., et al. The 200-MeV proton therapy project at the Paul Scherrer Institute: Conceptual design and practical realization. Med Phys 22 (1995) 37-53
26. Healey J.H., and Lane J.M. Chordoma: A critical review of diagnosis and treatment. Orthop Clin North Am 20 (1989) 417-426
27. Rutz H.P., and Lomax A.J. Donut-shaped high-dose configuration for proton beam radiation therapy. Strahlenther Onkol 181 (2005) 49-53
28. Lomax A. Intensity modulation methods for proton radiotherapy. Phys Med Biol 44 (1999) 185-205
29. Paganetti H., Niemierko A., Ancukiewicz M., et al. Relative biological effectiveness (RBE) values for proton beam therapy. Int J Radiat Oncol Biol Phys 53 (2002) 407-421
30. Gueulette J., Blattmann H., Pedroni E., et al. Relative biologic effectiveness determination in mouse intestine for scanning proton beam at Paul Scherrer Institute, Switzerland: Influence of motion. Int J Radiat Oncol Biol Phys 62 (2005) 838-845
31. Marucci L., Niemierko A., Liebsch N.J., et al. Spinal cord tolerance to high-dose fractionated 3D conformal proton-photon irradiation as evaluated by equivalent uniform dose and dose volume histogram analysis. Int J Radiat Oncol Biol Phys 59 (2004) 551-555
32. Kaplan E.L., and Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 53 (1958) 457-481
33. Common Terminology Criteria for Adverse Events. http://ctep.info.nih.gov/reporting/ctc.html. Accessed September 26, 2006.
34. Morin O., Gillis A., Chen J., et al. Megavoltage cone-beam CT: System description and clinical applications. Med Dosim 31 (2006) 51-61
35. Sillanpaa J., Chang J., Mageras G., et al. Developments in megavoltage cone beam CT with an amorphous silicon EPID: Reduction of exposure and synchronization with respiratory gating. Med Phys 32 (2005) 819-829
36. O'Connell J.X., Renard L.G., Liebsch N.J., et al. Base of skull chordoma: A correlative study of histologic and clinical features of 62 cases. Cancer 74 (1994) 2261-2267
37. Casali P.G., Messina A., Stacchiotti S., et al. Imatinib mesylate in chordoma. Cancer 101 (2004) 2086-2097
38. Burger H., den Bakker M.A., Kros J.M., et al. Activating mutations in c-KIT and PDGFRalpha are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes. Cancer Biol Ther 4 (2005) 1270-1274
39. Hall E.J. Intensity-modulated radiation therapy, protons, and the risk of second cancers. Int J Radiat Oncol Biol Phys 65 (2006) 1-7
40. Rutz H.P., Mirimanoff R.O., and Little J.B. Strategies for the prevention of treatment-induced secondary cancer. In: Nygaard F., and Upton A.C. (Eds). Anticarcinogenesis and radiation protection 2 (1991), Plenum Press, New York 39-45
41. Miralbell R., Lomax A., Cella L., et al. Potential reduction of the incidence of radiation-induced second cancers by using proton beams in the treatment of pediatric tumors. Int J Radiat Oncol Biol Phys 54 (2002) 824-829
42. Park L., Delaney T.F., Liebsch N.J., et al. Sacral chordomas: Impact of high-dose proton/photon-beam radiation therapy combined with or without surgery for primary versus recurrent tumor. Int J Radiat Oncol Biol Phys 65 (2006) 1514-1521