Optical imaging as an expansion of nuclear medicine: Cerenkov-based luminescence vs fluorescence-based luminescence

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 40, Issue 8, 2013, Pages 1283-1291

  Chin, Patrick T K ^a   Welling, Mick M ^a   Meskers, Stefan C J ^b   Valdes Olmos, Renato A ^a,c   Tanke, Hans ^a   Van Leeuwen, Fijs W B ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

Author keywords

Cerenkov; Fluorescence; Image guided surgery; Multimodal imaging; Nuclear medicine

Indexed keywords

FLUORESCEIN; FLUORESCENT DYE; FLUORODEOXYGLUCOSE F 18; METHYLENE BLUE;

CERENKOV LUMINESCENCE IMAGING; FLUORESCENCE IMAGING; HUMAN; INTERMETHOD COMPARISON; LUMINESCENCE; MOLECULAR IMAGING; NUCLEAR MEDICINE; QUANTUM YIELD; RADIOACTIVITY; REVIEW; SENSITIVITY ANALYSIS; SENTINEL LYMPH NODE BIOPSY;

FLUORESCENT DYES; HUMANS; LUMINESCENT MEASUREMENTS; MULTIMODAL IMAGING; NUCLEAR MEDICINE; OPTICAL IMAGING; POSITRON-EMISSION TOMOGRAPHY; SURGERY, COMPUTER-ASSISTED;

EID: 84879938033     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-013-2408-9     Document Type: Review

References (54)

1. Phelps ME. PET: the merging of biology and imaging into molecular imaging. J Nucl Med 2000;41:661-81.
2. Histed SN, Lindenberg ML, Mena E, Turkbey B, Choyke PL, Kurdziel KA. Review of functional/anatomical imaging in oncology. Nucl Med Commun 2012;33:349-61.
3. Kim WW, Kim JS, Hur SM, Kim SH, Lee S-K, Choi JH, et al. Radioguided surgery using an intraoperative PET probe for tumor localization and verification of complete resection in differentiated thyroid cancer: a pilot study. Surgery 2011;149:416-24.
4. Wahl RL, Quint LE, Cieslak RD, Aisen AM, Koeppe RA, Meyer CR. "Anatometabolic" tumor imaging: fusion of FDG PET with CT or MRI to localize foci of increased activity. J Nucl Med 1993;34:1190-7.
5. Ichise M, Chung D-G, Wang P, Wortzman G, Gray BG, Franks W. Technetium-99m-HMPAO SPECT, CT and MRI in the evaluation of patients with chronic traumatic brain injury: a correlation with neuropsychological performance. J Nucl Med 1994;35:217-26.
6. Buckle T, van Leeuwen AC, Chin PTK, Janssen H, Muller SH, Jonkers J, et al. A self-assembled multimodal complex for combined pre- and intraoperative imaging of the sentinel lymph node. Nanotechnology 2010;21:355101.
7. van der Poel HG, Buckle T, Brouwer OR, Valdés Olmos RA, van Leeuwen FWB. Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer. Eur Urol 2011;60:826-33.
8. van den Berg NS, Brouwer OR, Klop WMC, Balm AJ, van den Brekel M, Valdés Olmos RA, et al. A hybrid tracer for concomitant radio- and fluorescence guided sentinel lymph node biopsy in oral cavity cancer. J Nucl Med 2012;53(Suppl 1):1666.
9. Chang H-C, Chung C-K. The development of fluorescence imaging systems for clinical applications - part I, broad-field fluorescence imaging. Int J Instrum Sci 2012;1:16-20.
10. van den Berg NS, van Leeuwen FWB, van der Poel HG. Fluorescence guidance in urologic surgery. Curr Opin Urol 2012;22:109-20.
11. Magnan P. Detection of visible photons in CCD and CMOS: a comparative view. Nucl Instrum Methods Phys Res A 2003;504:199-212.
12. Troyan SL, Kianzad V, Gibbs-Strauss SL, Gioux S, Matsui A, Oketokoun R, et al. The FLARE™ intraoperative near-infrared fluorescence imaging system: a first-in-human clinical trial in breast cancer sentinel lymph node mapping. Ann Surg Oncol 2009;16:2943-52.
13. Spinelli AE, Boschi F. Optimizing in vivo small animal Cerenkov luminescence imaging. J Biomed Opt 2012;17:040506.
14. Robertson R, Germanos MS, Li C, Mitchell GS, Cherry ST, Silva MD. Optical imaging of Cerenkov light generation from positron-emitting radiotracers. Phys Med Biol 2009;54:N355-65.
15. van Leeuwen AC, Buckle T, Bendle G, Vermeeren L, Valdés Olmos R, van der Poel HG, et al. Tracer-cocktail injections for combined pre- and intraoperative multimodal imaging of lymph nodes in a spontaneous mouse prostate tumor model. J Biomed Opt 2011;16:016004.
16. Bhushan KR, Misra P, Liu F, Mathur S, Lenkinski RE, Frangioni JV. Detection of breast cancer microcalcifications using a dual-modality SPECT/NIR fluorescent probe. J Am Chem Soc 2008;130:17648-9.
17. Thorp-Greenwood FL, Coogan MP. Multimodal radio- (PET/SPECT) and fluorescence imaging agents based on metallo-radioisotopes: current applications and prospects for development of new agents. Dalton Trans 2011;40:6129-43.
18. Xu Y, Chang E, Liu H, Jiang H, Gambhir SS, Cheng Z. Proof-of-concept study of monitoring cancer drug therapy with Cerenkov luminescence imaging. J Nucl Med 2012;53:312-7.
19. Holland JP, Normand G, Ruggiero A, Lewis JS, Grimm J. Intraoperative imaging of positron emission tomographic radiotracers using Cerenkov luminescence emissions. Mol Imaging 2011;10:177-86.
20. Culver J, Akers W, Achilefu S. Multimodality molecular imaging with combined optical and SPECT/PET modalities. J Nucl Med 2008;49:169-72.
21. Alford R, Ogawa M, Choyke PL, Kobayashi H. Molecular probes for the in vivo imaging of cancer. Mol Biosyst 2009;5:1279-91.
22. Huang Y-Y, Chen AC-H, Hamblin M. Low-level laser therapy: an emerging clinical paradigm. SPIE Newsroom. doi: 10.1117/2.1200906.1669.
23. Lubart R, Lavie R, Friedman H. The penetration of white light through human tissue. Photomed Laser Surg 2005;23:435-6.
24. Chin PTK, Beekman CA, Buckle T, Josephson L, van Leeuwen FWB. Multispectral visualization of surgical safety-margins using fluorescent marker seeds. Am J Nucl Med Mol Imaging 2012;2:151-62.
25. Mourant JR, Fuselier T, Boyer J, Johnson TM, Bigio IJ. Predictions and measurements of scattering and absorption over broad wavelength ranges in tissue phantoms. Appl Opt 1997;36:949-57.
26. Andersson-Engels S, Klinteberg C, Svanberg K, Svanberg S. In vivo fluorescence imaging for tissue diagnostics. Phys Med Biol 1997;42:815-24.
27. Reibel Y, Jung M, Bouhifd M, Cunin B, Draman C. CCD or CMOS camera noise characterisation. Eur Phys J Appl Phys 2003;21:75-80.
28. Cerenkov PA. Visible radiation produced by electrons moving in a medium with velocities exceeding that of light. Phys Rev 1937;52:378-9.
29. Cho JS, Taschereau R, Olma S, Liu K, Chen YC, Shen CKF, et al. Cerenkov radiation imaging as a method for quantitative measurements of beta particles in a microfluidic chip. Phys Med Biol 2009;54:6757-71.
30. Wu JC, Sundaresan G, Iyer M, Gambhir SS. Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. Mol Ther 2001;4:297-306.
31. Contag CH, Spilman SD, Contag PR, Oshiro M, Eames B, Dennery P, et al. Visualizing gene expression in living mammals using a bioluminescent reporter. Photochem Photobiol 1997;66:523-31.
32. Mitchell GS, Gill RK, Boucher DL, Li C, Cherry SR. In vivo Cerenkov luminescence imaging: a new tool for molecular imaging. Philos Transact A Math Phys Eng Sci 2011;369:4605-19.
33. Frank IM, Tamm IE. Coherent visible radiation of fast electrons passing through matter. Dokl Akad Nauk SSSR 1937;14:109-14.
34. Pfennig G, Klewe-Nebenius H, Seelmann-Eggebert W. Karlsruher Nuklidkarte. 6th ed. Lage: Haberbeck; 1998.
35. Stübel H. Die Fluoreszenz tierischer Gewebe in ultraviolettem Licht. Pflugers Arch Physiol 1911;142:1-14.
36. Weissleder R, Ntziachristos V. Shedding light onto live molecular targets. Nat Med 2003;9:123-8.
37. Ntziachristos V. Fluorescence molecular imaging. Annu Rev Biomed Eng 2006;8:1-33.
38. Frangioni JV. In vivo near-infrared fluorescence imaging. Curr Opin Chem Biol 2003;7:626-34.
39. Moore GE, Peyton WT, French LA, Walker WW. The clinical use of fluorescein in neurosurgery; the localization of brain tumors. J Neurosurg 1948;5:392-8.
40. Alander JT, Kaartinen I, Laakso A, Pätilä T, Spillmann T, Tuchin VV, et al. A review of indocyanine green fluorescent imaging in surgery. Int J Biomed Imaging 2012;2012:940585.
41. Martin MM, Lindqvist L. The pH dependence of fluorescein fluorescence. J Lumin 1975;10:381-90.
42. Lavis LD, Raines RT. Bright ideas for chemical biology. ACS Chem Biol 2008;3:142-55.
43. Concepts in digital imaging technology quantum efficiency http://learn.hamamatsu.com/articles/quantumefficiency.html.
44. Brouwer OR, Klop MWC, Buckle T, Vermeeren L, van den Brekel MWM, Balm FJM, Nieweg OE, et al. Feasibility of sentinel node biopsy in head and neck melanoma using a hybrid radioactive and fluorescent tracer. Ann Surg Oncol 2012;19:1988-94.
45. Brouwer OR, Buckle T, Vermeeren L, Klop WMC, Balm AJM, van der Poel HG, et al. Comparing the hybrid fluorescent-radioactive tracer indocyanine green-99mTc-nanocolloid with 99mTc-nanocolloid for sentinel node identification: a validation study using lymphoscintigraphy and SPECT/CT. J Nucl Med 2012;53:1034-40.
46. Buckle T, Brouwer OR, Valdés Olmos RA, van der Poel HG, van Leeuwen FWB. Relation between intraprostatic tracer deposits and sentinel lymph node mapping in prostate cancer patients. J Nucl Med 2012;53:1026-33.
47. Lee S-K, Mills A. Luminescence of leuco-thiazine dyes. J Fluoresc 2003;13:375-7.
48. Landsman MLJ, Kwant G, Mook GA, Zijlstra WG. Light-absorbing properties, stability, and spectral stabilization of indocyanine green. J Appl Physiol 1976;40:575-83.
49. Kuil J, Velders AH, van Leeuwen FWB. Multimodal tumor-targeting peptides functionalized with both a radio- and a fluorescent-label. Bioconjug Chem 2010;21:1709-19.
50. Ruggiero A, Holland JP, Lewis JS, Grimm J. Cerenkov luminescence imaging of medical isotopes. J Nucl Med 2010;51:1123-30.
51. Grimm J, Schöder H. Non-invasive Cerenkov luminescence imaging of lymphoma, leukemia and metastatic lymph nodes. 2012. http://www.ClinicalTrails. gov, Identifier: NCT01664936.
52. Dothager RS, Goiffon RJ, Jackson E, Harpstrite S, Piwnica-Worms D. Cerenkov radiation energy transfer (CRET) imaging: a novel method for optical imaging of PET isotopes in biological systems. PLoS One 2010;5:e13300.
53. Kothapalli S-R, Liu H, Liao JC, Cheng Z, Gambhir SS. Endoscopic imaging of Cerenkov luminescence. Biomed Opt Express 2012;3:1215-25.
54. Liu H, Carpenter CM, Jiang H, Pratx G, Sun C, Buchin MP, et al. Intraoperative imaging of tumors using Cerenkov luminescence endoscopy: a feasibility experimental study. J Nucl Med 2012;53:1579-84.