Colocalization of thin-walled dome regions with low hemodynamic wall shear stress in unruptured cerebral aneurysms: Clinical article

Journal of Neurosurgery

Volumn 119, Issue 1, 2013, Pages 172-179

  Kadasi, Laith M ^a,b   Dent, Walter C ^a   Malek, Adel M ^a,b  

^a TUFTS MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aneurysm; Hemodynamics; Intraoperative microscopy; Pressure; Shear stress; Vascular disorders; Wall thickness

Indexed keywords

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BRAIN DEGENERATION; CLINICAL ARTICLE; COMPUTATIONAL FLUID DYNAMICS; FEMALE; HEMODYNAMICS; HUMAN; INTRAOPERATIVE PERIOD; MALE; MICROSCOPY; PRIORITY JOURNAL; SACCULAR ANEURYSM; SHEAR STRESS; STEADY STATE; UNRUPTURED INTRACRANIAL ANEURYSM;

ADULT; CEREBRAL ANGIOGRAPHY; CEREBRAL ARTERIES; CEREBROVASCULAR CIRCULATION; FEMALE; HEMODYNAMICS; HUMANS; INTRACRANIAL ANEURYSM; LOGISTIC MODELS; MALE; MATCHED-PAIR ANALYSIS; MIDDLE AGED; MODELS, CARDIOVASCULAR; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; PULSATILE FLOW; STRESS, MECHANICAL;

EID: 84879921057     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2013.2.JNS12968     Document Type: Article

References (36)

1. Abruzzo T, Shengelaia GG, Dawson RC III, Owens DS, Cawley CM, Gravanis MB: Histologic and morphologic comparison of experimental aneurysms with human intracranial aneurysms. AJNR Am J Neuroradiol 19:1309-1314, 1998
2. Asari S, Ohmoto T: Growth and rupture of unruptured cerebral aneurysms based on the intraoperative appearance. Acta Med Okayama 48:257-262, 1994
3. Baharoglu MI, Schirmer CM, Hoit DA, Gao BL, Malek AM: Aneurysm inflow-angle as a discriminant for rupture in sidewall cerebral aneurysms: morphometric and computational fluid dynamic analysis. Stroke 41:1423-1430, 2010
4. Boussel L, Rayz V, McCulloch C, Martin A, Acevedo-Bolton G, Lawton M, et al: Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study. Stroke 39:2997-3002, 2008
5. Castro MA, Putman CM, Sheridan MJ, Cebral JR: Hemodynamic patterns of anterior communicating artery aneurysms: a possible association with rupture. AJNR Am J Neuroradiol 30:297-302, 2009
6. Cebral JR, Castro MA, Burgess JE, Pergolizzi RS, Sheridan MJ, Putman CM: Characterization of cerebral aneurysms for assessing risk of rupture by using patient-specific computational hemodynamics models. AJNR Am J Neuroradiol 26: 2550-2559, 2005
7. Cebral JR, Mut F, Weir J, Putman CM: Association of hemodynamic characteristics and cerebral aneurysm rupture. AJNR Am J Neuroradiol 32:264-270, 2011
8. Chappell DC, Varner SE, Nerem RM, Medford RM, Alexander RW: Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium. Circ Res 82:532-539, 1998
9. Chien S: Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell. Am J Physiol Heart Circ Physiol 292:H1209-H1224, 2007
10. Cho A, Mitchell L, Koopmans D, Langille BL: Effects of changes in blood flow rate on cell death and cell proliferation in carotid arteries of immature rabbits. Circ Res 81:328-337, 1997
11. Dai G, Kaazempur-Mofrad MR, Natarajan S, Zhang Y, Vaughn S, Blackman BR, et al: Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis- susceptible and -resistant regions of human vasculature. Proc Natl Acad Sci U S A 101:14871-14876, 2004
12. De Keulenaer GW, Chappell DC, Ishizaka N, Nerem RM, Alexander RW, Griendling KK: Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circ Res 82:1094-1101, 1998
13. Frösen J, Piippo A, Paetau A, Kangasniemi M, Niemelä M, Hernesniemi J, et al: Remodeling of saccular cerebral artery aneurysm wall is associated with rupture: histological analysis of 24 unruptured and 42 ruptured cases. Stroke 35:2287-2293, 2004
14. Hassan T, Timofeev EV, Saito T, Shimizu H, Ezura M, Matsumoto Y, et al: A proposed parent vessel geometry-based categorization of saccular intracranial aneurysms: computational flow dynamics analysis of the risk factors for lesion rupture. J Neurosurg 103:662-680, 2005
15. Hayakawa M, Katada K, Anno H, Imizu S, Hayashi J, Irie K, et al: CT angiography with electrocardiographically gated reconstruction for visualizing pulsation of intracranial aneurysms: identification of aneurysmal protuberance presumably associated with wall thinning. AJNR Am J Neuroradiol 26:1366-1369, 2005
16. Hop JW, Rinkel GJE, Algra A, van Gijn J: Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review. Stroke 28:660-664, 1997
17. Jou LD, Lee DH, Morsi H, Mawad ME: Wall shear stress on ruptured and unruptured intracranial aneurysms at the internal carotid artery. AJNR Am J Neuroradiol 29:1761-1767, 2008
18. Kadasi LM, Dent WC, Malek AM: Cerebral aneurysm wall thickness analysis using intraoperative microscopy: effect of size and gender on thin translucent regions. J Neurointervent Surg [epub ahead of print], 2012
19. Kolega J, Gao L, Mandelbaum M, Mocco J, Siddiqui AH, Natarajan SK, et al: Cellular and molecular responses of the basilar terminus to hemodynamics during intracranial aneurysm initiation in a rabbit model. J Vasc Res 48:429-442, 2011
20. Kondo S, Hashimoto N, Kikuchi H, Hazama F, Nagata I, Kataoka H: Apoptosis of medial smooth muscle cells in the development of saccular cerebral aneurysms in rats. Stroke 29:181-189, 1998
21. Kraiss LW, Geary RL, Mattsson EJR, Vergel S, Au YPT, Clowes AW: Acute reductions in blood flow and shear stress induce platelet-derived growth factor-A expression in baboon prosthetic grafts. Circ Res 79:45-53, 1996
22. Lindekleiv HM, Valen-Sendstad K, Morgan MK, Mardal KA, Faulder K, Magnus JH, et al: Sex differences in intracranial arterial bifurcations. Gend Med 7:149-155, 2010
23. Malek AM, Alper SL, Izumo S: Hemodynamic shear stress and its role in atherosclerosis. JAMA 282:2035-2042, 1999
24. Meng H, Wang Z, Hoi Y, Gao L, Metaxa E, Swartz DD, et al: Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation. Stroke 38:1924-1931, 2007
25. Mizoi K, Yoshimoto T, Nagamine Y: Types of unruptured cerebral aneurysms reviewed from operation video-recordings. Acta Neurochir (Wien) 138:965-969, 1996
26. Molyneux AJ, Kerr RSC, Yu LM, Clarke M, Sneade M, Yarnold JA, et al: International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Lancet 366:809-817, 2005
27. Nixon AM, Gunel M, Sumpio BE: The critical role of hemodynamics in the development of cerebral vascular disease. A review. J Neurosurg 112:1240-1253, 2010
28. Raaymakers TWM, Rinkel GJE, Limburg M, Algra A: Mortality and morbidity of surgery for unruptured intracranial aneurysms: a meta-analysis. Stroke 29:1531-1538, 1998
29. Schirmer CM, Malek AM: Prediction of complex flow patterns in intracranial atherosclerotic disease using computational fluid dynamics. Neurosurgery 61:842-852, 2007
30. Shojima M, Oshima M, Takagi K, Torii R, Hayakawa M, Katada K, et al: Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms. Stroke 35:2500-2505, 2004
31. Tardy Y, Resnick N, Nagel T, Gimbrone MA Jr., Dewey CF Jr.: Shear stress gradients remodel endothelial monolayers in vitro via a cell proliferation-migration-loss cycle. Arterioscler Thromb Vasc Biol 17:3102-3106, 1997
32. Tuttle JL, Nachreiner RD, Bhuller AS, Condict KW, Connors BA, Herring BP, et al: Shear level influences resistance artery remodeling: wall dimensions, cell density, and eNOS expression. Am J Physiol Heart Circ Physiol 281:H1380-H1389, 2001
33. van Gijn J, Rinkel GJE: Subarachnoid haemorrhage: diagnosis, causes and management. Brain 124:249-278, 2001
34. Wang Z, Kolega J, Hoi Y, Gao L, Swartz DD, Levy EI, et al: Molecular alterations associated with aneurysmal remodeling are localized in the high hemodynamic stress region of a created carotid bifurcation. Neurosurgery 65:169-178, 2009
35. Wiebers DO, Whisnant JP, Huston J III, Meissner I, Brown RD Jr., Piepgras DG, et al: Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. Lancet 362:103-110, 2003
36. Xiang J, Natarajan SK, Tremmel M, Ma D, Mocco J, Hopkins LN, et al: Hemodynamic-morphologic discriminants for intracranial aneurysm rupture. Stroke 42:144-152, 2011