Downregulation of T-cell lymphoma invasion and metastasis-inducing factor 1 induces cytoskeletal rearrangement and inhibits the invasive capacity of gastric cancer cells

Molecular Medicine Reports

Volumn 8, Issue 2, 2013, Pages 425-433

  Zhu, Jin Ming ^a   Yu, Pei Wu ^b  

^a JINAN MILITARY GENERAL HOSPITAL   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cytoskeleton; Gastric cancer; Invasion; T cell lymphoma invasion and metastasis inducing factor 1

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CYTOSKELETON PROTEIN; ONCOPROTEIN; TIAM 1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL INVASION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE REARRANGEMENT; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; IN VITRO STUDY; LIPOSOMAL GENE DELIVERY SYSTEM; METASTASIS POTENTIAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH ADENOCARCINOMA; T LYMPHOCYTE SUBPOPULATION;

CELL LINE, TUMOR; CYTOSKELETON; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; NEOPLASM INVASIVENESS; RNA, ANTISENSE; RNA, MESSENGER; STOMACH NEOPLASMS;

EID: 84879897538     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1513     Document Type: Article

References (31)

1. Mahar AL, McLeod RS, Kiss A, Paszat L and Coburn NG: A systematic review of the effect of institution and surgeon factors on surgical outcomes for gastric cancer. J Am Coll Surg 214: 860-868, 2012.
2. Lee JH, Kim KM, Cheong JH and Noh SH: Current management and future strategies of gastric cancer. Yonsei Med J 53: 248-257, 2012.
3. Lin LL, Huang HC and Juan HF: Discovery of biomarkers for gastric cancer: a proteomics approach. J Proteomics 75: 3081-3097, 2012.
4. Habets GG, Scholtes EH, Zuydgeest D, van der Kammen RA, Stam JC, Berns A and Collard JG: Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell 77: 537-549, 1994.
5. Habets GG, van der Kammen RA, Jenkins NA, Gilbert DJ, Copeland NG, Hagemeijer A and Collard JG: The invasion-inducing TIAM1 gene maps to human chromosome band 21q22 and mouse chromosome 16. Cytogenet Cell Genet 70: 48-51, 1995.
6. Mertens AE, Roovers RC and Collard JG: Regulation of Tiam1-Rac signalling. FEBS Lett 546: 11-16, 2003.
7. Minard ME, Kim LS, Price JE and Gallick GE: The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression. Breast Cancer Res Treat 84: 21-32, 2004.
8. Chen B, Ding Y, Liu F, et al: Tiam1, overexpressed in most malignancies, is a novel tumor biomarker. Mol Med Rep 5: 48-53, 2012.
9. Ding Y, Chen B, Wang S, et al: Overexpression of Tiam1 in hepatocellular carcinomas predicts poor prognosis of HCC patients. Int J Cancer 124: 653-658, 2009.
10. Minard ME, Ellis LM and Gallick GE: Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. Clin Exp Metastasis 23: 301-313, 2006.
11. Zhu JM, Yu PW and Zhao YL: Relationship between the expression of Tiam-1, Rac 1 and the pathobiological behavior of gastric cancer. Chin J Gen Surg 14: 168-172, 2005.
12. Chen XR, Ren WP, Dong JF, Xiao SD and Sloane BF: Screening of gastric cancer cell sublines by adhesion method in vitro. Chin J Gastroenterol 2: 121-124, 2001.
13. Yokozaki H: Molecular characteristics of eight gastric cancer cell lines established in Japan. Pathol Int 50: 767-777, 2000.
14. Li ZZ, Zhang L, Mao HT, Wang Y, Li DH and Gui SL: Effect of Tiam-1 antisense oligodeoxynucleotides (ASODNS) on antimetastasis of tumor. Chin J Cancer Biother 50: 767-777, 2000.
15. Zhang XQ, Zhang R, Gu CH and Wang YM: Expression level of ICAM-1 on cultured cells measured quantitatively with cellular ELISA. Acta Acad Med Mil Tert 23: 117-118, 2001.
16. Zhang JH, Ding YQ and Yang XJ: Introduction of a reforming staining method for cytoskeletal proteins. J Diag Pathol 3: 235-236, 1996.
17. Albini A, Iwamoto Y, Kleinman HK, Martin GR, Aaronson SA, Kozlowski JM and McEwan RN: A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 47: 3239-3245, 1987.
18. Lleonart ME, Martin-Duque P, Sanchez-Prieto R, Moreno A and Ramon y Cajal S: Tumor heterogeneity: morphological, molecular and clinical implications. Histol Histopathol 15: 881-898, 2000.
19. Marian AJ: Molecular genetic studies of complex phenotypes. Transl Res 159: 64-79, 2012.
20. Prasun P, Pradhan M and Agarwal S: One gene, many phenotypes. J Postgrad Med 53: 257-261, 2007.
21. Etienne MS and Hall A: Rho GTPases in cell biology. Nature 420: 629-635, 2002.
22. Malliri A and Collard JG: Role of Rho-family proteins in cell adhesion and cancer. Curr Opin Cell Biol 15: 583-589, 2003.
23. Hirohashi S and Kanai Y: Cell adhesion system and human cancer morphogenesis. Cancer Sci 94: 575-581, 2003.
24. Ben-Ze'ev A: The cytoskeleton in cancer cells. Biochim Biophys Acta 780: 197-212, 1985.
25. Ehler E, van Leeuwen F, Collard JG and Salinas PC: Expression of Tiam-1 in the developing brain suggests a role for the Tiam-1-Rac signaling pathway in cell migration and neurite outgrowth. Mol Cell Neurosci 9: 1-12, 1997.
26. Okegawa T, Pong RC, Li Y and Hsieh JT: The role of cell adhesion molecule in cancer progression and its application in cancer therapy. Acta Biochim Pol 51: 445-457, 2004.
27. Marhaba R and Zoller M: CD44 in cancer progression: adhesion, migration and growth regulation. J Mol Histol 35: 211-231, 2004.
28. Ekblom P, Lonai P and Talts JF: Expression and biological role of laminin-1. Matrix Biol 22: 35-47, 2003.
29. Kim WH, Lee BL, Jun SH, Song SY and Kleinman HK: Expression of 32/67-kDa laminin receptor in laminin adhesion-selected human colon cancer cell lines. Br J Cancer 77: 15-20, 1998.
30. Kim WH, Jun SH, Kibbey MC, Thompson EW and Kleinman HK: Expression of beta 1 integrin in laminin-adhesion-selected human colon cancer cell lines of varying tumorigenicity. Invasion Metastasis 14: 147-155, 1994-1995.
31. Brábek J, Mierke CT, Rösel D, Veselý P and Fabry B: The role of the tissue microenvironment in the regulation of cancer cell motility and invasion. Cell Commun Signal 8: 22, 2010.